"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids. Nat Commun. 2021 06 28; 12(1):3987.
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An Epigenome-Wide Association Study of Obesity-Related Traits. Am J Epidemiol. 2018 08 01; 187(8):1662-1669.
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Epigenome-Wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis. Gastroenterology. 2017 10; 153(4):1096-1106.e2.
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Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study. Clin Epigenetics. 2017; 9:15.
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Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease. JAMA Neurol. 2015 Jan; 72(1):15-24.
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Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation. Br J Haematol. 2010 Jan; 148(1):69-79.