 Interferon-gamma
"Interferon-gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
| Descriptor ID |
D007371
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| MeSH Number(s) |
D12.644.276.374.440.893 D12.644.276.374.480.350 D12.644.276.374.480.615.350 D12.644.276.718.550 D12.776.467.374.440.893 D12.776.467.374.480.350 D12.776.467.374.480.615.350 D12.776.467.718.550 D23.529.374.440.893 D23.529.374.480.350 D23.529.374.480.615.350 D23.529.718.550
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| Concept/Terms |
Interferon-gamma- Interferon-gamma
- Interferon, gamma
- gamma-Interferon
- Type II Interferon
- Interferon, Type II
- Interferon Type II
- Interferon, Immune
- Immune Interferon
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Below are MeSH descriptors whose meaning is more general than "Interferon-gamma".
Below are MeSH descriptors whose meaning is more specific than "Interferon-gamma".
This graph shows the total number of publications written about "Interferon-gamma" by people in this website by year, and whether "Interferon-gamma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 2 | 2 | 4 | | 1999 | 2 | 3 | 5 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 4 | 4 | | 2002 | 1 | 4 | 5 | | 2003 | 0 | 3 | 3 | | 2004 | 0 | 3 | 3 | | 2005 | 1 | 3 | 4 | | 2006 | 3 | 3 | 6 | | 2007 | 4 | 6 | 10 | | 2008 | 0 | 4 | 4 | | 2009 | 1 | 2 | 3 | | 2010 | 2 | 3 | 5 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 5 | 6 | | 2013 | 0 | 3 | 3 | | 2014 | 2 | 3 | 5 | | 2015 | 0 | 3 | 3 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 4 | 1 | 5 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Interferon-gamma" by people in Profiles.
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Houser MC, Caudle WM, Chang J, Kannarkat GT, Yang Y, Kelly SD, Oliver D, Joers V, Shannon KM, Keshavarzian A, Tansey MG. Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. Acta Neuropathol Commun. 2021 08 19; 9(1):139.
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Roehle K, Qiang L, Ventre KS, Heid D, Ali LR, Lenehan P, Heckler M, Crowley SJ, Stump CT, Ro G, Godicelj A, Bhuiyan AM, Yang A, Quiles Del Rey M, Biary T, Luoma AM, Bruck PT, Tegethoff JF, Nopper SL, Li J, Byrne KT, Pelletier M, Wucherpfennig KW, Stanger BZ, Akin JJ, Mancias JD, Agudo J, Dougan M, Dougan SK. cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Sci Transl Med. 2021 05 19; 13(594).
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Samelko L, Caicedo M, McAllister K, Jacobs J, Hallab NJ. Metal-induced delayed type hypersensitivity responses potentiate particle induced osteolysis in a sex and age dependent manner. PLoS One. 2021; 16(5):e0251885.
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Cogswell A, Ferguson N, Barker E. Presence of Inflammatory Group I and III Innate Lymphoid Cells in the Colon of Simian Immunodeficiency Virus-Infected Rhesus Macaques. J Virol. 2020 04 16; 94(9).
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Cogswell AC, Maski K, Scammell TE, Tucker D, Orban ZS, Koralnik IJ. Children with Narcolepsy type 1 have increased T-cell responses to orexins. Ann Clin Transl Neurol. 2019 12; 6(12):2566-2572.
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Castleman MJ, Dillon SM, Purba C, Cogswell AC, McCarter M, Barker E, Wilson C. Enteric bacteria induce IFN? and Granzyme B from human colonic Group 1 Innate Lymphoid Cells. Gut Microbes. 2020 11 09; 12(1):1667723.
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Doyle EH, Rahman A, Aloman C, Klepper AL, El-Shamy A, Eng F, Rocha C, Kim S, Haydel B, Florman SS, Fiel MI, Schiano T, Branch AD. Individual liver plasmacytoid dendritic cells are capable of producing IFNa and multiple additional cytokines during chronic HCV infection. PLoS Pathog. 2019 07; 15(7):e1007935.
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Zhang S, Kohli K, Black RG, Yao L, Spadinger SM, He Q, Pillarisetty VG, Cranmer LD, Van Tine BA, Yee C, Pierce RH, Riddell SR, Jones RL, Pollack SM. Systemic Interferon-? Increases MHC Class I Expression and T-cell Infiltration in Cold Tumors: Results of a Phase 0 Clinical Trial. Cancer Immunol Res. 2019 08; 7(8):1237-1243.
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Castleman MJ, Dillon SM, Purba CM, Cogswell AC, Kibbie JJ, McCarter MD, Santiago ML, Barker E, Wilson CC. Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFN? Production From Human Colonic ILC3s via Multiple Mechanisms. Front Immunol. 2019; 10:649.
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Duette G, Pereyra Gerber P, Rubione J, Perez PS, Landay AL, Crowe SM, Liao Z, Witwer KW, Holgado MP, Salido J, Geffner J, Sued O, Palmer CS, Ostrowski M. Induction of HIF-1a by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation. mBio. 2018 09 11; 9(5).
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