 Insulin
"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
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| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
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| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
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Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1988 | 0 | 2 | 2 | | 1989 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 1 | 2 | 3 | | 2004 | 0 | 1 | 1 | | 2005 | 1 | 3 | 4 | | 2006 | 1 | 1 | 2 | | 2007 | 2 | 2 | 4 | | 2008 | 2 | 5 | 7 | | 2009 | 4 | 1 | 5 | | 2010 | 3 | 1 | 4 | | 2011 | 3 | 1 | 4 | | 2012 | 2 | 2 | 4 | | 2013 | 3 | 3 | 6 | | 2014 | 5 | 3 | 8 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 2 | 3 | | 2017 | 3 | 0 | 3 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 1 | 7 | 8 | | 2021 | 3 | 3 | 6 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Witkowski P, Anteby R, Olaitan OK, Forbes RC, Niederhaus S, Ricordi C, Fair JH, Harland RC. Pancreatic Islets Quality and Potency Cannot be Verified as Required for Drugs: Reflection on the FDA Review of a Biological License Application for Human Islets. Transplantation. 2021 12 01; 105(12):e409-e410.
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Pulipati VP, Amblee A, Yap SET, Shaka H, Tahsin B, Fogelfeld L. Hypertriglyceridemia-associated acute pancreatitis: Response to continuous insulin infusion. PLoS One. 2021; 16(11):e0260495.
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Ruddock-Walker S, Shaaban S, Jacobson JL, Meltzer L, Minutti CZ, Hovey SW. Improving Timeliness of Insulin Administration by Using an Insulin Dose Calculator. Hosp Pediatr. 2021 10; 11(10):1163-1173.
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Cheng YC, Guerra Y, Morkos M, Tahsin B, Onyenwenyi C, Fogg L, Fogelfeld L. Insulin management in hospitalized patients with diabetes mellitus on high-dose glucocorticoids: Management of steroid-exacerbated hyperglycemia. PLoS One. 2021; 16(9):e0256682.
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Verdier M, DeMott JM, Peksa GD. A comparison of insulin doses for treatment of hyperkalaemia in intensive care unit patients with renal insufficiency. Aust Crit Care. 2022 05; 35(3):258-263.
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Arvanitakis Z, Capuano AW, Wang HY, Schneider JA, Kapasi A, Bennett DA, Ahima RS, Arnold SE. Brain insulin signaling and cerebrovascular disease in human postmortem brain. Acta Neuropathol Commun. 2021 04 15; 9(1):71.
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Bishehsari F, Engen PA, Adnan D, Sarrafi S, Wilber S, Shaikh M, Green SJ, Naqib A, Giron LB, Abdel-Mohsen M, Keshavarzian A. Abnormal food timing and predisposition to weight gain: Role of barrier dysfunction and microbiota. Transl Res. 2021 05; 231:113-123.
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Santos CAQ, Conover C, Shehab N, Geller AI, Guerra YS, Kramer H, Kosacz NM, Zhang H, Budnitz DS, Trick WE. Electronic Measurement of a Clinical Quality Measure for Inpatient Hypoglycemic Events: A Multicenter Validation Study. Med Care. 2020 10; 58(10):927-933.
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Arvanitakis Z, Wang HY, Capuano AW, Khan A, Taïb B, Anokye-Danso F, Schneider JA, Bennett DA, Ahima RS, Arnold SE. Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function. Ann Neurol. 2020 09; 88(3):513-525.
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Saande CJ, Bries AE, Pritchard SK, Nass CA, Reed CH, Rowling MJ, Schalinske KL. Whole Egg Consumption Decreases Cumulative Weight Gain in Diet-Induced Obese Rats. J Nutr. 2020 07 01; 150(7):1818-1823.
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