"Dendritic Spines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spiny processes on DENDRITES, each of which receives excitatory input from one nerve ending (NERVE ENDINGS). They are commonly found on PURKINJE CELLS and PYRAMIDAL CELLS.
| Descriptor ID |
D049229
|
| MeSH Number(s) |
A08.675.256.200 A11.284.180.225.169 A11.671.240.169
|
| Concept/Terms |
Dendritic Spines- Dendritic Spines
- Dendritic Spine
- Spine, Dendritic
- Spines, Dendritic
|
Below are MeSH descriptors whose meaning is more general than "Dendritic Spines".
Below are MeSH descriptors whose meaning is more specific than "Dendritic Spines".
This graph shows the total number of publications written about "Dendritic Spines" by people in this website by year, and whether "Dendritic Spines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dendritic Spines" by people in Profiles.
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Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not ?-Amyloid Accumulation. Cell Rep. 2020 09 22; 32(12):108169.
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A? mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease. J Neurosci. 2018 01 31; 38(5):1085-1099.
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Mechanism-based treatments in neurodevelopmental disorders: fragile X syndrome. Pediatr Neurol. 2014 Apr; 50(4):297-302.
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Spatially restricted actin-regulatory signaling contributes to synapse morphology. J Neurochem. 2012 Jun; 121(6):852-60.
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Fragile X syndrome and targeted treatment trials. Results Probl Cell Differ. 2012; 54:297-335.
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Reversal of fragile X phenotypes by manipulation of A?PP/A? levels in Fmr1KO mice. PLoS One. 2011; 6(10):e26549.
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Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch Gen Psychiatry. 2010 May; 67(5):448-57.
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Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons. J Comp Neurol. 2009 Jan 20; 512(3):399-418.
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Distance-dependent differences in synapse number and AMPA receptor expression in hippocampal CA1 pyramidal neurons. Neuron. 2006 May 04; 50(3):431-42.