"Separase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Separase is a caspase-like cysteine protease, which plays a central role in triggering ANAPHASE by cleaving the SCC1/RAD21 subunit of the cohesin complex. Cohesin holds the sister CHROMATIDS together during METAPHASE and its cleavage results in chromosome segregation.
| Descriptor ID |
D064247
|
| MeSH Number(s) |
D08.811.277.656.262.500.792 D08.811.277.656.300.200.792 D12.776.167.552
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Separase".
Below are MeSH descriptors whose meaning is more specific than "Separase".
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Below are the most recent publications written about "Separase" by people in Profiles.