 Transforming Growth Factor beta1
"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
| Descriptor ID |
D053773
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| MeSH Number(s) |
D12.644.276.374.687.100 D12.644.276.954.800.720.100 D12.644.276.963.720.100 D12.776.467.374.687.100 D12.776.467.942.800.720.100 D12.776.467.960.720.100 D23.529.374.687.100 D23.529.942.800.720.100 D23.529.960.720.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta1".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta1".
This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in this website by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 2 | 3 | | 2011 | 3 | 2 | 5 | | 2012 | 1 | 1 | 2 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta1" by people in Profiles.
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Rezvani SN, Chen J, Li J, Midura R, Cali V, Sandy JD, Plaas A, Wang VM. In-Vivo Efficacy of Recombinant Human Hyaluronidase (rHuPH20) Injection for Accelerated Healing of Murine Retrocalcaneal Bursitis and Tendinopathy. J Orthop Res. 2020 01; 38(1):59-69.
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Sikes KJ, Li J, Gao SG, Shen Q, Sandy JD, Plaas A, Wang VM. TGF-b1 or hypoxia enhance glucose metabolism and lactate production via HIF1A signaling in tendon cells. Connect Tissue Res. 2018 09; 59(5):458-471.
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Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017 Jan 13; 292(2):732-747.
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Luo W, Sandy J, Trella K, Gorski D, Gao S, Li J, Brounts S, Galante J, Plaas A. Degenerative Suspensory Ligament Desmitis (DSLD) in Peruvian Paso Horses Is Characterized by Altered Expression of TGFß Signaling Components in Adipose-Derived Stromal Fibroblasts. PLoS One. 2016; 11(11):e0167069.
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Cross JA, Cole BJ, Spatny KP, Sundman E, Romeo AA, Nicholson GP, Wagner B, Fortier LA. Leukocyte-Reduced Platelet-Rich Plasma Normalizes Matrix Metabolism in Torn Human Rotator Cuff Tendons. Am J Sports Med. 2015 Dec; 43(12):2898-906.
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Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR. Integrin avß6 promotes an osteolytic program in cancer cells by upregulating MMP2. Cancer Res. 2014 Mar 01; 74(5):1598-608.
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Bell R, Li J, Shewman EF, Galante JO, Cole BJ, Bach BR, Troy KL, Mikecz K, Sandy JD, Plaas AH, Wang VM. ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy. J Orthop Res. 2013 Oct; 31(10):1540-8.
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Bell R, Li J, Gorski DJ, Bartels AK, Shewman EF, Wysocki RW, Cole BJ, Bach BR, Mikecz K, Sandy JD, Plaas AH, Wang VM. Controlled treadmill exercise eliminates chondroid deposits and restores tensile properties in a new murine tendinopathy model. J Biomech. 2013 Feb 01; 46(3):498-505.
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Fischer B, Dimopoulou A, Egerer J, Gardeitchik T, Kidd A, Jost D, Kayserili H, Alanay Y, Tantcheva-Poor I, Mangold E, Daumer-Haas C, Phadke S, Peirano RI, Heusel J, Desphande C, Gupta N, Nanda A, Felix E, Berry-Kravis E, Kabra M, Wevers RA, van Maldergem L, Mundlos S, Morava E, Kornak U. Further characterization of ATP6V0A2-related autosomal recessive cutis laxa. Hum Genet. 2012 Nov; 131(11):1761-73.
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Wang M, Shen J, Jin H, Im HJ, Sandy J, Chen D. Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis. Ann N Y Acad Sci. 2011 Dec; 1240:61-9.
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