Transforming Growth Factor beta1
"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
| Descriptor ID |
D053773
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| MeSH Number(s) |
D12.644.276.374.687.100 D12.644.276.954.775.100 D12.776.467.374.687.100 D12.776.467.942.775.100 D23.529.374.687.100 D23.529.942.775.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta1".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta1".
This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in this website by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transforming Growth Factor beta1" by people in Profiles.
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Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1. J Biol Chem. 2017 Jan 13; 292(2):732-747.
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Col1A1 production and apoptotic resistance in TGF-ß1-induced epithelial-to-mesenchymal transition-like phenotype of 603B cells. PLoS One. 2012; 7(12):e51371.
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Further characterization of ATP6V0A2-related autosomal recessive cutis laxa. Hum Genet. 2012 Nov; 131(11):1761-73.
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Growth factor delivery through self-assembling peptide scaffolds. Clin Orthop Relat Res. 2011 Oct; 469(10):2716-24.
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Effect of self-assembling peptide, chondrogenic factors, and bone marrow-derived stromal cells on osteochondral repair. Osteoarthritis Cartilage. 2010 Dec; 18(12):1608-19.
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Porous implants as drug delivery vehicles to augment host tissue integration. FASEB J. 2008 Jun; 22(6):1684-93.
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Depressed bone mineralization following high dose TGF-beta1 application in an orthopedic implant model. Calcif Tissue Int. 2005 May; 76(5):379-84.