Bone Morphogenetic Proteins
"Bone Morphogenetic Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
| Descriptor ID |
D019485
|
| MeSH Number(s) |
D12.644.276.954.200 D12.776.467.942.200 D23.529.942.200
|
| Concept/Terms |
Bone Morphogenetic Proteins- Bone Morphogenetic Proteins
- Morphogenetic Proteins, Bone
- Bone Morphogenetic Protein
- Morphogenetic Protein, Bone
|
Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Proteins".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Proteins".
This graph shows the total number of publications written about "Bone Morphogenetic Proteins" by people in this website by year, and whether "Bone Morphogenetic Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bone Morphogenetic Proteins" by people in Profiles.
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Sclerostin neutralization unleashes the osteoanabolic effects of Dkk1 inhibition. JCI Insight. 2018 06 07; 3(11).
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Acute Phosphate Restriction Impairs Bone Formation and Increases Marrow Adipose Tissue in Growing Mice. J Bone Miner Res. 2016 12; 31(12):2204-2214.
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Sclerostin antibody treatment improves implant fixation in a model of severe osteoporosis. J Bone Joint Surg Am. 2015 Jan 21; 97(2):133-40.
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Sclerostin antibody prevents particle-induced implant loosening by stimulating bone formation and inhibiting bone resorption in a rat model. Arthritis Rheum. 2012 Dec; 64(12):4012-20.
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BMP-7 protects against progression of cartilage degeneration after impact injury. J Orthop Res. 2009 May; 27(5):602-11.
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Effects induced by BMPS in cultures of human articular chondrocytes: comparative studies. Growth Factors. 2008 Oct; 26(5):275-83.
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Response of human chondrocytes prepared for autologous implantation to growth factors. J Knee Surg. 2008 Jul; 21(3):192-9.
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OP-1/BMP-7 in cartilage repair. Int Orthop. 2007 Dec; 31(6):773-81.
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Safety of epidural administration of Osteogenic Protein-1 (OP-1/BMP-7): behavioral and macroscopic observation. Spine (Phila Pa 1976). 2007 Jun 01; 32(13):1388-93.
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Anti-catabolic effect of OP-1 in chronically compressed intervertebral discs. J Orthop Res. 2007 Apr; 25(4):517-30.