"Mutagenesis, Insertional" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
Descriptor ID |
D016254
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MeSH Number(s) |
E05.393.420.601.550 G05.365.590.575 G05.558.550
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Concept/Terms |
Sequence Insertion- Sequence Insertion
- Insertion, Sequence
- Insertions, Sequence
- Sequence Insertions
Gene Insertion- Gene Insertion
- Gene Insertions
- Insertion, Gene
- Insertions, Gene
Insertion Mutation- Insertion Mutation
- Insertion Mutations
- Mutation, Insertion
- Mutations, Insertion
Insertional Activation- Insertional Activation
- Activation, Insertional
- Activations, Insertional
- Insertional Activations
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Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Insertional".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Insertional".
This graph shows the total number of publications written about "Mutagenesis, Insertional" by people in this website by year, and whether "Mutagenesis, Insertional" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mutagenesis, Insertional" by people in Profiles.
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Novel and recurrent EMD mutations in patients with Emery-Dreifuss muscular dystrophy, identify exon 2 as a mutation hot spot. J Hum Genet. 2011 Aug; 56(8):589-94.
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Sudden infant death syndrome: rare mutation in the serotonin system FEV gene. Pediatr Res. 2007 Aug; 62(2):180-2.