 Folic Acid Deficiency
"Folic Acid Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
| Descriptor ID |
D005494
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| MeSH Number(s) |
C18.654.521.500.133.699.308
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| Concept/Terms |
Folic Acid Deficiency- Folic Acid Deficiency
- Deficiency, Folic Acid
- Acid Deficiencies, Folic
- Acid Deficiency, Folic
- Deficiencies, Folic Acid
- Folic Acid Deficiencies
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Below are MeSH descriptors whose meaning is more general than "Folic Acid Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Folic Acid Deficiency".
This graph shows the total number of publications written about "Folic Acid Deficiency" by people in this website by year, and whether "Folic Acid Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2007 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Folic Acid Deficiency" by people in Profiles.
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Saande CJ, Pritchard SK, Worrall DM, Snavely SE, Nass CA, Neuman JC, Luchtel RA, Dobiszewski S, Miller JW, Vailati-Riboni M, Loor JJ, Schalinske KL. Dietary Egg Protein Prevents Hyperhomocysteinemia via Upregulation of Hepatic Betaine-Homocysteine S-Methyltransferase Activity in Folate-Restricted Rats. J Nutr. 2019 08 01; 149(8):1369-1376.
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Shammo JM, Usha L, Richardson KJ, Elliott E, Dewdney S, Venugopal P, Cobleigh M, Kuzel TM. Olaparib-Induced Severe Folate Deficiency in a Patient With Advanced Ovarian Cancer. J Oncol Pract. 2019 07; 15(7):405-407.
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Tangney CC, Tang Y, Evans DA, Morris MC. Biochemical indicators of vitamin B12 and folate insufficiency and cognitive decline. Neurology. 2009 Jan 27; 72(4):361-7.
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Morris MC, Tangney CC. Is dietary intake of folate too low? Lancet. 2007 Jan 20; 369(9557):166-7.
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