 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 4 | 2 | 6 | | 1982 | 4 | 1 | 5 | | 1983 | 3 | 0 | 3 | | 1984 | 1 | 0 | 1 | | 1985 | 2 | 0 | 2 | | 1986 | 3 | 1 | 4 | | 1987 | 6 | 0 | 6 | | 1988 | 6 | 0 | 6 | | 1989 | 6 | 0 | 6 | | 1990 | 9 | 0 | 9 | | 1991 | 6 | 0 | 6 | | 1992 | 5 | 0 | 5 | | 1993 | 9 | 0 | 9 | | 1994 | 5 | 0 | 5 | | 1995 | 4 | 0 | 4 | | 1996 | 6 | 1 | 7 | | 1997 | 7 | 0 | 7 | | 1998 | 13 | 0 | 13 | | 1999 | 12 | 2 | 14 | | 2000 | 17 | 1 | 18 | | 2001 | 9 | 1 | 10 | | 2002 | 17 | 1 | 18 | | 2003 | 28 | 0 | 28 | | 2004 | 14 | 0 | 14 | | 2005 | 15 | 3 | 18 | | 2006 | 23 | 3 | 26 | | 2007 | 27 | 3 | 30 | | 2008 | 26 | 1 | 27 | | 2009 | 27 | 6 | 33 | | 2010 | 28 | 2 | 30 | | 2011 | 36 | 1 | 37 | | 2012 | 18 | 3 | 21 | | 2013 | 35 | 5 | 40 | | 2014 | 35 | 2 | 37 | | 2015 | 24 | 2 | 26 | | 2016 | 37 | 5 | 42 | | 2017 | 39 | 2 | 41 | | 2018 | 37 | 3 | 40 | | 2019 | 27 | 4 | 31 | | 2020 | 42 | 3 | 45 | | 2021 | 28 | 3 | 31 | | 2022 | 13 | 1 | 14 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Hess SP, Levin M, Akram F, Woo K, Andersen L, Trenkle K, Brown P, Ouyang B, Fleisher JE. The impact and feasibility of a brief, virtual, educational intervention for home healthcare professionals on Parkinson's Disease and Related Disorders: pilot study of I SEE PD Home. BMC Med Educ. 2022 Jun 28; 22(1):506.
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Adrissi J, Fleisher J. Moving the Dial Toward Equity in Parkinson's Disease Clinical Research: a Review of Current Literature and Future Directions in Diversifying PD Clinical Trial Participation. Curr Neurol Neurosci Rep. 2022 Aug; 22(8):475-483.
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Voigt RM, Wang Z, Brown JM, Engen PA, Naqib A, Goetz CG, Hall DA, Metman LV, Shaikh M, Forsyth CB, Keshavarzian A. Gut microbial metabolites in Parkinson's disease: Association with lifestyle, disease characteristics, and treatment status. Neurobiol Dis. 2022 Aug; 170:105780.
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Manfready RA, Forsyth CB, Voigt RM, Hall DA, Goetz CG, Keshavarzian A. Gut-Brain Communication in Parkinson's Disease: Enteroendocrine Regulation by GLP-1. Curr Neurol Neurosci Rep. 2022 07; 22(7):335-342.
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Mitchell T, Wilkes BJ, Archer DB, Chu WT, Coombes SA, Lai S, McFarland NR, Okun MS, Black ML, Herschel E, Simuni T, Comella C, Afshari M, Xie T, Li H, Parrish TB, Kurani AS, Corcos DM, Vaillancourt DE. Advanced diffusion imaging to track progression in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Neuroimage Clin. 2022; 34:103022.
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Halloway S, Desai P, Beck T, Aggarwal N, Agarwal P, Evans D, Rajan KB. Association of Neurofilament Light With the Development and Severity of Parkinson Disease. Neurology. 2022 05 31; 98(22):e2185-e2193.
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Khalil H, Aldaajani ZF, Aldughmi M, Al-Sharman A, Mohammad T, Mehanna R, El-Jaafary SI, Dahshan A, Ben Djebara M, Kamel WA, Amer HA, Farghal M, Abdulla F, Al-Talai N, Snineh MA, Farhat N, Jamali FA, Matar RK, Abdelraheem HS, Ghonimi NAM, Al-Melh MA, Elbhrawy S, Alotaibi MS, Elaidy SA, Almuammar SA, Al-Hashel JY, Gouider R, Samir H, Mhiri C, Skorvanek M, Lin J, Martinez-Martin P, Stebbins GT, Luo S, Goetz CG, Bajwa JA. Validation of the Arabic Version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale. Mov Disord. 2022 04; 37(4):826-841.
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Killinger BA, Marshall LL, Chatterjee D, Chu Y, Bras J, Guerreiro R, Kordower JH. In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain. Proc Natl Acad Sci U S A. 2022 02 01; 119(5).
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Pal G, Mangone G, Hill EJ, Ouyang B, Liu Y, Lythe V, Ehrlich D, Saunders-Pullman R, Shanker V, Bressman S, Alcalay RN, Garcia P, Marder KS, Aasly J, Mouradian MM, Link S, Rosenbaum M, Anderson S, Bernard B, Wilson R, Stebbins G, Nichols WC, Welter ML, Sani S, Afshari M, Verhagen L, de Bie RMA, Foltynie T, Hall D, Corvol JC, Goetz CG. Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers. Ann Neurol. 2022 03; 91(3):424-435.
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Bailey M, Anderson S, Stebbins G, Barnes L, Shulman LM, Tartakovsky J, Hall DA. Comparison of motor, non-motor, and quality of life phenotype in Black and White patients with Parkinson's disease. Parkinsonism Relat Disord. 2022 03; 96:18-21.
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