 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 4 | 2 | 6 | | 1982 | 4 | 1 | 5 | | 1983 | 3 | 0 | 3 | | 1984 | 1 | 0 | 1 | | 1985 | 2 | 0 | 2 | | 1986 | 3 | 1 | 4 | | 1987 | 6 | 0 | 6 | | 1988 | 6 | 0 | 6 | | 1989 | 6 | 0 | 6 | | 1990 | 9 | 0 | 9 | | 1991 | 6 | 0 | 6 | | 1992 | 5 | 0 | 5 | | 1993 | 9 | 0 | 9 | | 1994 | 5 | 0 | 5 | | 1995 | 4 | 0 | 4 | | 1996 | 6 | 1 | 7 | | 1997 | 7 | 0 | 7 | | 1998 | 13 | 0 | 13 | | 1999 | 12 | 2 | 14 | | 2000 | 17 | 1 | 18 | | 2001 | 9 | 1 | 10 | | 2002 | 17 | 1 | 18 | | 2003 | 27 | 0 | 27 | | 2004 | 14 | 0 | 14 | | 2005 | 15 | 3 | 18 | | 2006 | 23 | 3 | 26 | | 2007 | 27 | 3 | 30 | | 2008 | 26 | 1 | 27 | | 2009 | 27 | 6 | 33 | | 2010 | 28 | 2 | 30 | | 2011 | 36 | 1 | 37 | | 2012 | 18 | 3 | 21 | | 2013 | 36 | 5 | 41 | | 2014 | 35 | 2 | 37 | | 2015 | 24 | 2 | 26 | | 2016 | 37 | 5 | 42 | | 2017 | 38 | 2 | 40 | | 2018 | 35 | 2 | 37 | | 2019 | 9 | 0 | 9 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Schwarzschild MA, Macklin EA, Bakshi R, Battacharyya S, Logan R, Espay AJ, Hung AY, Bwala G, Goetz CG, Russell DS, Goudreau JL, Parashos SA, Saint-Hilaire MH, Rudolph A, Hare JM, Curhan GC, Ascherio A. Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial. Neurology. 2019 10 01; 93(14):e1328-e1338.
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Nwabuobi L, Barbosa W, Sweeney M, Oyler S, Meisel T, Di Rocco A, Chodosh J, Fleisher JE. Sex-related differences in homebound advanced Parkinson's disease patients. Clin Interv Aging. 2019; 14:1371-1377.
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Del Din S, Galna B, Godfrey A, Bekkers EMJ, Pelosin E, Nieuwhof F, Mirelman A, Hausdorff JM, Rochester L. Analysis of Free-Living Gait in Older Adults With and Without Parkinson's Disease and With and Without a History of Falls: Identifying Generic and Disease-Specific Characteristics. J Gerontol A Biol Sci Med Sci. 2019 03 14; 74(4):500-506.
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Zhong Z, Merkitch D, Karaman MM, Zhang J, Sui Y, Goldman JG, Zhou XJ. High-Spatial-Resolution Diffusion MRI in Parkinson Disease: Lateral Asymmetry of the Substantia Nigra. Radiology. 2019 04; 291(1):149-157.
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Diederich NJ, James Surmeier D, Uchihara T, Grillner S, Goetz CG. Parkinson's disease: Is it a consequence of human brain evolution? Mov Disord. 2019 04; 34(4):453-459.
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van Kessel SP, Frye AK, El-Gendy AO, Castejon M, Keshavarzian A, van Dijk G, El Aidy S. Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson's disease. Nat Commun. 2019 01 18; 10(1):310.
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Hoogland J, Boel JA, de Bie RMA, Schmand BA, Geskus RB, Dalrymple-Alford JC, Marras C, Adler CH, Weintraub D, Junque C, Pedersen KF, Mollenhauer B, Goldman JG, Tröster AI, Burn DJ, Litvan I, Geurtsen GJ. Risk of Parkinson's disease dementia related to level I MDS PD-MCI. Mov Disord. 2019 03; 34(3):430-435.
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Huang X, Fan H, Li J, Jones JA, Wang EQ, Chen L, Chen X, Liu H. External cueing facilitates auditory-motor integration for speech control in individuals with Parkinson's disease. Neurobiol Aging. 2019 04; 76:96-105.
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Kochanski RB, Shils J, Verhagen Metman L, Pal G, Sani S. Analysis of Movement-Related Beta Oscillations in the Off-Medication State During Subthalamic Nucleus Deep Brain Stimulation Surgery. J Clin Neurophysiol. 2019 Jan; 36(1):67-73.
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Perez-Pardo P, Dodiya HB, Engen PA, Forsyth CB, Huschens AM, Shaikh M, Voigt RM, Naqib A, Green SJ, Kordower JH, Shannon KM, Garssen J, Kraneveld AD, Keshavarzian A. Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice. Gut. 2019 05; 68(5):829-843.
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