 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 4 | 2 | 6 | | 1982 | 4 | 1 | 5 | | 1983 | 3 | 0 | 3 | | 1984 | 1 | 0 | 1 | | 1985 | 2 | 0 | 2 | | 1986 | 3 | 1 | 4 | | 1987 | 6 | 0 | 6 | | 1988 | 6 | 0 | 6 | | 1989 | 6 | 0 | 6 | | 1990 | 9 | 0 | 9 | | 1991 | 6 | 0 | 6 | | 1992 | 5 | 0 | 5 | | 1993 | 9 | 0 | 9 | | 1994 | 5 | 0 | 5 | | 1995 | 5 | 0 | 5 | | 1996 | 7 | 1 | 8 | | 1997 | 7 | 1 | 8 | | 1998 | 13 | 0 | 13 | | 1999 | 12 | 2 | 14 | | 2000 | 17 | 1 | 18 | | 2001 | 9 | 1 | 10 | | 2002 | 17 | 1 | 18 | | 2003 | 27 | 0 | 27 | | 2004 | 14 | 0 | 14 | | 2005 | 15 | 3 | 18 | | 2006 | 23 | 3 | 26 | | 2007 | 27 | 3 | 30 | | 2008 | 26 | 1 | 27 | | 2009 | 27 | 6 | 33 | | 2010 | 28 | 2 | 30 | | 2011 | 36 | 1 | 37 | | 2012 | 18 | 3 | 21 | | 2013 | 35 | 5 | 40 | | 2014 | 35 | 2 | 37 | | 2015 | 24 | 2 | 26 | | 2016 | 37 | 5 | 42 | | 2017 | 38 | 2 | 40 | | 2018 | 32 | 2 | 34 | | 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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van Kessel SP, Frye AK, El-Gendy AO, Castejon M, Keshavarzian A, van Dijk G, El Aidy S. Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson's disease. Nat Commun. 2019 01 18; 10(1):310.
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Kochanski RB, Shils J, Verhagen Metman L, Pal G, Sani S. Analysis of Movement-Related Beta Oscillations in the Off-Medication State During Subthalamic Nucleus Deep Brain Stimulation Surgery. J Clin Neurophysiol. 2019 Jan; 36(1):67-73.
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Perez-Pardo P, Dodiya HB, Engen PA, Forsyth CB, Huschens AM, Shaikh M, Voigt RM, Naqib A, Green SJ, Kordower JH, Shannon KM, Garssen J, Kraneveld AD, Keshavarzian A. Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice. Gut. 2019 05; 68(5):829-843.
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Hall DA, Moore C, Comella C. Recruitment of patients with de novo Parkinson disease: successful strategies in a randomized exercise clinical trial. Trials. 2018 Nov 14; 19(1):630.
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Bledsoe IO, Stebbins GT, Merkitch D, Goldman JG. White matter abnormalities in the corpus callosum with cognitive impairment in Parkinson disease. Neurology. 2018 12 11; 91(24):e2244-e2255.
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Weiss A, Herman T, Mirelman A, Shiratzky SS, Giladi N, Barnes LL, Bennett DA, Buchman AS, Hausdorff JM. The transition between turning and sitting in patients with Parkinson's disease: A wearable device detects an unexpected sequence of events. Gait Posture. 2019 01; 67:224-229.
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Holden SK, Medina LD, Hoyt B, Sillau SH, Berman BD, Goldman JG, Weintraub D, Kluger BM. Validation of a performance-based assessment of cognitive functional ability in Parkinson's disease. Mov Disord. 2018 11; 33(11):1760-1768.
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Hoogland J, van Wanrooij LL, Boel JA, Goldman JG, Stebbins GT, Dalrymple-Alford JC, Marras C, Adler CH, Junque C, Pedersen KF, Mollenhauer B, Zabetian CP, Eslinger PJ, Lewis SJG, Wu RM, Klein M, Rodriguez-Oroz MC, Cammisuli DM, Barone P, Biundo R, de Bie RMA, Schmand BA, Tröster AI, Burn DJ, Litvan I, Filoteo JV, Geurtsen GJ, Weintraub D. Detecting Mild Cognitive Deficits in Parkinson's Disease: Comparison of Neuropsychological Tests. Mov Disord. 2018 11; 33(11):1750-1759.
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Beach TG, Serrano GE, Kremer T, Canamero M, Dziadek S, Sade H, Derkinderen P, Corbillé AG, Letournel F, Munoz DG, White CL, Schneider J, Crary JF, Sue LI, Adler CH, Glass MJ, Intorcia AJ, Walker JE, Foroud T, Coffey CS, Ecklund D, Riss H, Goßmann J, König F, Kopil CM, Arnedo V, Riley L, Linder C, Dave KD, Jennings D, Seibyl J, Mollenhauer B, Chahine L. Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4). J Neuropathol Exp Neurol. 2018 09 01; 77(9):793-802.
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Postuma RB, Poewe W, Litvan I, Lewis S, Lang AE, Halliday G, Goetz CG, Chan P, Slow E, Seppi K, Schaffer E, Rios-Romenets S, Mi T, Maetzler C, Li Y, Heim B, Bledsoe IO, Berg D. Validation of the MDS clinical diagnostic criteria for Parkinson's disease. Mov Disord. 2018 10; 33(10):1601-1608.
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