 Parkinson Disease
"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
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| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
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| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
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Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 4 | 2 | 6 | | 1982 | 4 | 1 | 5 | | 1983 | 3 | 0 | 3 | | 1984 | 1 | 0 | 1 | | 1985 | 2 | 0 | 2 | | 1986 | 3 | 1 | 4 | | 1987 | 6 | 0 | 6 | | 1988 | 6 | 0 | 6 | | 1989 | 6 | 0 | 6 | | 1990 | 9 | 0 | 9 | | 1991 | 6 | 0 | 6 | | 1992 | 5 | 0 | 5 | | 1993 | 9 | 0 | 9 | | 1994 | 5 | 0 | 5 | | 1995 | 4 | 0 | 4 | | 1996 | 6 | 1 | 7 | | 1997 | 7 | 0 | 7 | | 1998 | 13 | 0 | 13 | | 1999 | 12 | 2 | 14 | | 2000 | 17 | 1 | 18 | | 2001 | 9 | 1 | 10 | | 2002 | 17 | 1 | 18 | | 2003 | 28 | 0 | 28 | | 2004 | 14 | 0 | 14 | | 2005 | 15 | 3 | 18 | | 2006 | 23 | 3 | 26 | | 2007 | 27 | 3 | 30 | | 2008 | 26 | 1 | 27 | | 2009 | 27 | 6 | 33 | | 2010 | 28 | 2 | 30 | | 2011 | 36 | 1 | 37 | | 2012 | 18 | 3 | 21 | | 2013 | 35 | 5 | 40 | | 2014 | 35 | 2 | 37 | | 2015 | 24 | 2 | 26 | | 2016 | 37 | 5 | 42 | | 2017 | 39 | 2 | 41 | | 2018 | 37 | 3 | 40 | | 2019 | 27 | 4 | 31 | | 2020 | 13 | 1 | 14 |
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Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Kordower JH, Okun MS, Jankovic J. Reply to: "Toward a Personalized Approach to Parkinson's Cell Therapy". Mov Disord. 2020 11; 35(11):2120-2121.
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Friedman JH, Goetz CG. Apathy in Parkinson disease: Why we should care. Neurology. 2020 11 17; 95(20):893-894.
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Fleisher JE, Sennott BJ, Myrick E, Niemet CJ, Lee M, Whitelock CM, Sanghvi M, Liu Y, Ouyang B, Hall DA, Comella CL, Chodosh J. KICK OUT PD: Feasibility and quality of life in the pilot karate intervention to change kinematic outcomes in Parkinson's Disease. PLoS One. 2020; 15(9):e0237777.
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Jankovic J, Okun MS, Kordower JH. Stem Cells: Scientific and Ethical Quandaries of a Personalized Approach to Parkinson's Disease. Mov Disord. 2020 08; 35(8):1312-1314.
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Vitek JL, Jain R, Chen L, Tröster AI, Schrock LE, House PA, Giroux ML, Hebb AO, Farris SM, Whiting DM, Leichliter TA, Ostrem JL, San Luciano M, Galifianakis N, Verhagen Metman L, Sani S, Karl JA, Siddiqui MS, Tatter SB, Ul Haq I, Machado AG, Gostkowski M, Tagliati M, Mamelak AN, Okun MS, Foote KD, Moguel-Cobos G, Ponce FA, Pahwa R, Nazzaro JM, Buetefisch CM, Gross RE, Luca CC, Jagid JR, Revuelta GJ, Takacs I, Pourfar MH, Mogilner AY, Duker AP, Mandybur GT, Rosenow JM, Cooper SE, Park MC, Khandhar SM, Sedrak M, Phibbs FT, Pilitsis JG, Uitti RJ, Starr PA. Subthalamic nucleus deep brain stimulation with a multiple independent constant current-controlled device in Parkinson's disease (INTREPID): a multicentre, double-blind, randomised, sham-controlled study. Lancet Neurol. 2020 06; 19(6):491-501.
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Del Din S, Galna B, Lord S, Nieuwboer A, Bekkers EMJ, Pelosin E, Avanzino L, Bloem BR, Olde Rikkert MGM, Nieuwhof F, Cereatti A, Della Croce U, Mirelman A, Hausdorff JM, Rochester L. Falls Risk in Relation to Activity Exposure in High-Risk Older Adults. J Gerontol A Biol Sci Med Sci. 2020 05 22; 75(6):1198-1205.
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Bolier E, Bot M, van den Munckhof P, Pal G, Sani S, Stebbins GT, Verhagen Metman L. Kinesthetic Cells within the Subthalamic Nucleus and Deep Brain Stimulation for Parkinson Disease. World Neurosurg. 2020 07; 139:e784-e791.
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Lindestam Arlehamn CS, Dhanwani R, Pham J, Kuan R, Frazier A, Rezende Dutra J, Phillips E, Mallal S, Roederer M, Marder KS, Amara AW, Standaert DG, Goldman JG, Litvan I, Peters B, Sulzer D, Sette A. a-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease. Nat Commun. 2020 04 20; 11(1):1875.
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Pelosin E, Cerulli C, Ogliastro C, Lagravinese G, Mori L, Bonassi G, Mirelman A, Hausdorff JM, Abbruzzese G, Marchese R, Avanzino L. A Multimodal Training Modulates Short Afferent Inhibition and Improves Complex Walking in a Cohort of Faller Older Adults With an Increased Prevalence of Parkinson's Disease. J Gerontol A Biol Sci Med Sci. 2020 03 09; 75(4):722-728.
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Keshavarzian A, Engen P, Bonvegna S, Cilia R. The gut microbiome in Parkinson's disease: A culprit or a bystander? Prog Brain Res. 2020; 252:357-450.
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