 Triiodothyronine
"Triiodothyronine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
| Descriptor ID |
D014284
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| MeSH Number(s) |
D06.472.931.740.385 D12.125.072.050.767.741.894
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| Concept/Terms |
Triiodothyronine- Triiodothyronine
- T3 Thyroid Hormone
- Thyroid Hormone, T3
- Liothyronine
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Below are MeSH descriptors whose meaning is more general than "Triiodothyronine".
Below are MeSH descriptors whose meaning is more specific than "Triiodothyronine".
This graph shows the total number of publications written about "Triiodothyronine" by people in this website by year, and whether "Triiodothyronine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1984 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1986 | 1 | 0 | 1 | | 1987 | 4 | 0 | 4 | | 1988 | 1 | 1 | 2 | | 1989 | 0 | 1 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 1 | 1 | 2 | | 1993 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 2 | 3 | | 2002 | 0 | 2 | 2 | | 2003 | 2 | 2 | 4 | | 2004 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 1 | 3 | 4 | | 2008 | 1 | 2 | 3 | | 2009 | 2 | 3 | 5 | | 2010 | 2 | 1 | 3 | | 2011 | 3 | 0 | 3 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 2 | 3 | | 2015 | 4 | 2 | 6 | | 2016 | 2 | 1 | 3 | | 2017 | 2 | 0 | 2 | | 2018 | 2 | 2 | 4 | | 2020 | 2 | 2 | 4 | | 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Triiodothyronine" by people in Profiles.
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Shakir MKM, Brooks DI, McAninch EA, Fonseca TL, Mai VQ, Bianco AC, Hoang TD. Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism. J Clin Endocrinol Metab. 2021 10 21; 106(11):e4400-e4413.
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Fonseca TL, Garcia T, Fernandes GW, Nair TM, Bianco AC. Neonatal thyroxine activation modifies epigenetic programming of the liver. Nat Commun. 2021 07 21; 12(1):4446.
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Jonklaas J, Bianco AC, Cappola AR, Celi FS, Fliers E, Heuer H, McAninch EA, Moeller LC, Nygaard B, Sawka AM, Watt T, Dayan CM. Evidence-Based Use of Levothyroxine/Liothyronine Combinations in Treating Hypothyroidism: A Consensus Document. Thyroid. 2021 02; 31(2):156-182.
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França MM, German A, Fernandes GW, Liao XH, Bianco AC, Refetoff S, Dumitrescu AM. Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism. Thyroid. 2021 02; 31(2):202-207.
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Ettleson MD, Bianco AC. Individualized Therapy for Hypothyroidism: Is T4 Enough for Everyone? J Clin Endocrinol Metab. 2020 09 01; 105(9).
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Idrees T, Palmer S, Maciel RMB, Bianco AC. Liothyronine and Desiccated Thyroid Extract in the Treatment of Hypothyroidism. Thyroid. 2020 10; 30(10):1399-1413.
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McKeever L, Peterson SJ, Lateef O, Freels S, Fonseca TL, Bocco BMLC, Fernandes GW, Roehl K, Nowak K, Mozer M, Bianco AC, Braunschweig CA. Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation. J Clin Endocrinol Metab. 2020 02 01; 105(2).
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Jo S, Fonseca TL, Bocco BMLC, Fernandes GW, McAninch EA, Bolin AP, Da Conceição RR, Werneck-de-Castro JP, Ignacio DL, Egri P, Németh D, Fekete C, Bernardi MM, Leitch VD, Mannan NS, Curry KF, Butterfield NC, Bassett JHD, Williams GR, Gereben B, Ribeiro MO, Bianco AC. Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain. J Clin Invest. 2019 01 02; 129(1):230-245.
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Da Conceição RR, Fernandes GW, Fonseca TL, Bocco BMLC, Bianco AC. Metal Coordinated Poly-Zinc-Liothyronine Provides Stable Circulating Triiodothyronine Levels in Hypothyroid Rats. Thyroid. 2018 11; 28(11):1425-1433.
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Bianco AC, Kim BS. Pathophysiological relevance of deiodinase polymorphism. Curr Opin Endocrinol Diabetes Obes. 2018 10; 25(5):341-346.
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