 Gemfibrozil
"Gemfibrozil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipid-regulating agent that lowers elevated serum lipids primarily by decreasing serum triglycerides with a variable reduction in total cholesterol.
| Descriptor ID |
D015248
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| MeSH Number(s) |
D02.241.081.114.968.500.750 D02.241.081.944.509.350 D02.355.726.305.750 D02.455.426.559.389.657.654.305.750 D10.251.400.895.593.350
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| Concept/Terms |
Ausgem- Ausgem
- Sigma Brand of Gemfibrozil
Bolutol- Bolutol
- Farmasierra Brand of Gemfibrozil
Decrelip- Decrelip
- Ferrer Brand of Gemfibrozil
Gemhexal- Gemhexal
- Hexal Brand of Gemfibrozil
Gen-Gemfibrozil- Gen-Gemfibrozil
- Gen Gemfibrozil
- GenGemfibrozil
- Genpharm Brand of Gemfibrozil
Jezil- Jezil
- Alphapharm Brand of Gemfibrozil
Lipazil- Lipazil
- Douglas Brand of Gemfibrozil
Litarek- Litarek
- Ipsen Brand of Gemfibrozil
Lopid- Lopid
- Lopid R
- Warner-Lambert Brand of Gemfibrozil
- Warner Lambert Brand of Gemfibrozil
- Pfizer Brand of Gemfibrozil
- United Drug Brand of Gemfibrozil
- Lipur
- Parke Davis Brand of Gemfibrozil
Nu-Gemfibrozil- Nu-Gemfibrozil
- Nu Gemfibrozil
- NuGemfibrozil
- Nu-Pharm Brand of Gemfibrozil
- Nu Pharm Brand of Gemfibrozil
Pilder- Pilder
- Quimifar Brand of Gemfibrozil
PMS-Gemfibrozil- PMS-Gemfibrozil
- PMS Gemfibrozil
- Pharmascience Brand of Gemfibrozil
Trialmin- Trialmin
- Menarini Brand of Gemfibrozil
Apo-Gemfibrozil- Apo-Gemfibrozil
- Apo Gemfibrozil
- ApoGemfibrozil
- Apotex Brand of Gemfibrozil
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Below are MeSH descriptors whose meaning is more general than "Gemfibrozil".
Below are MeSH descriptors whose meaning is more specific than "Gemfibrozil".
This graph shows the total number of publications written about "Gemfibrozil" by people in this website by year, and whether "Gemfibrozil" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2007 | 2 | 1 | 3 | | 2009 | 1 | 0 | 1 | | 2012 | 5 | 0 | 5 | | 2015 | 1 | 0 | 1 | | 2017 | 2 | 0 | 2 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Gemfibrozil" by people in Profiles.
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Gottschalk CG, Jana M, Roy A, Patel DR, Pahan K. Gemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease via PPARa-Dependent Astrocytic GDNF Pathway. J Neurosci. 2021 03 10; 41(10):2287-2300.
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Gottschalk CG, Roy A, Jana M, Kundu M, Pahan K. Activation of Peroxisome Proliferator-Activated Receptor-a Increases the Expression of Nuclear Receptor Related 1 Protein (Nurr1) in Dopaminergic Neurons. Mol Neurobiol. 2019 Nov; 56(11):7872-7887.
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Kim K, Kleinman HK, Lee HJ, Pahan K. Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders. Orphanet J Rare Dis. 2017 06 17; 12(1):113.
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Ghosh A, Rangasamy SB, Modi KK, Pahan K. Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis. J Neurochem. 2017 05; 141(3):423-435.
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Ghosh A, Jana M, Modi K, Gonzalez FJ, Sims KB, Berry-Kravis E, Pahan K. Activation of peroxisome proliferator-activated receptor a induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders. J Biol Chem. 2015 Apr 17; 290(16):10309-24.
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Ghosh A, Corbett GT, Gonzalez FJ, Pahan K. Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor a: implications for late infantile Batten disease therapy. J Biol Chem. 2012 Nov 09; 287(46):38922-35.
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Jana M, Mondal S, Gonzalez FJ, Pahan K. Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-ß. J Biol Chem. 2012 Oct 05; 287(41):34134-48.
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Corbett GT, Roy A, Pahan K. Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. J Immunol. 2012 Jul 15; 189(2):1002-13.
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Ghosh A, Pahan K. Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disorders. J Biol Chem. 2012 Aug 03; 287(32):27189-203.
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Jana M, Pahan K. Gemfibrozil, a lipid lowering drug, inhibits the activation of primary human microglia via peroxisome proliferator-activated receptor ß. Neurochem Res. 2012 Aug; 37(8):1718-29.
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