 Excitatory Amino Acid Antagonists
"Excitatory Amino Acid Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
| Descriptor ID |
D018691
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| MeSH Number(s) |
D27.505.519.625.190.300 D27.505.696.577.190.300
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| Concept/Terms |
Excitatory Amino Acid Antagonists- Excitatory Amino Acid Antagonists
- Antagonists, Excitatory Amino Acid
- Amino Acids, Excitatory, Antagonists
- Glutamate Receptor Antagonists
- Antagonists, Glutamate Receptor
- Receptor Antagonists, Glutamate
- EAA Antagonists
- Antagonists, EAA
- Glutamate Antagonists
- Antagonists, Glutamate
- Amino Acid Antagonists, Excitatory
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Below are MeSH descriptors whose meaning is more general than "Excitatory Amino Acid Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Excitatory Amino Acid Antagonists".
This graph shows the total number of publications written about "Excitatory Amino Acid Antagonists" by people in this website by year, and whether "Excitatory Amino Acid Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 2 | 1 | 3 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 3 | 3 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Excitatory Amino Acid Antagonists" by people in Profiles.
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Soorya LV, Fogg L, Ocampo E, Printen M, Youngkin S, Halpern D, Kolevzon A, Lee S, Grodberg D, Anagnostou E. Neurocognitive Outcomes from Memantine: A Pilot, Double-Blind, Placebo-Controlled Trial in Children with Autism Spectrum Disorder. J Child Adolesc Psychopharmacol. 2021 09; 31(7):475-484.
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Arvanitakis Z, Shah RC, Bennett DA. Diagnosis and Management of Dementia: Review. JAMA. 2019 10 22; 322(16):1589-1599.
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Hagerman R, Jacquemont S, Berry-Kravis E, Des Portes V, Stanfield A, Koumaras B, Rosenkranz G, Murgia A, Wolf C, Apostol G, von Raison F. Mavoglurant in Fragile X Syndrome: Results of two open-label, extension trials in adults and adolescents. Sci Rep. 2018 11 19; 8(1):16970.
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Youssef EA, Berry-Kravis E, Czech C, Hagerman RJ, Hessl D, Wong CY, Rabbia M, Deptula D, John A, Kinch R, Drewitt P, Lindemann L, Marcinowski M, Langland R, Horn C, Fontoura P, Santarelli L, Quiroz JA. Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results. Neuropsychopharmacology. 2018 02; 43(3):503-512.
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Herrold AA, Voigt RM, Napier TC. mGluR5 is necessary for maintenance of methamphetamine-induced associative learning. Eur Neuropsychopharmacol. 2013 Jul; 23(7):691-6.
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Manning SM, Boll G, Fitzgerald E, Selip DB, Volpe JJ, Jensen FE. The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain. Int J Dev Neurosci. 2011 Nov; 29(7):767-73.
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Buvanendran A, Kroin JS. Multimodal analgesia for controlling acute postoperative pain. Curr Opin Anaesthesiol. 2009 Oct; 22(5):588-93.
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Ishikawa M, Mu P, Moyer JT, Wolf JA, Quock RM, Davies NM, Hu XT, Schlüter OM, Dong Y. Homeostatic synapse-driven membrane plasticity in nucleus accumbens neurons. J Neurosci. 2009 May 06; 29(18):5820-31.
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Hagerman RJ, Berry-Kravis E, Kaufmann WE, Ono MY, Tartaglia N, Lachiewicz A, Kronk R, Delahunty C, Hessl D, Visootsak J, Picker J, Gane L, Tranfaglia M. Advances in the treatment of fragile X syndrome. Pediatrics. 2009 Jan; 123(1):378-90.
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Manning SM, Talos DM, Zhou C, Selip DB, Park HK, Park CJ, Volpe JJ, Jensen FE. NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia. J Neurosci. 2008 Jun 25; 28(26):6670-8.
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