"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
| Descriptor ID |
D016875
|
| MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
| Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2017 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "tau Proteins" by people in Profiles.
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APOE4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults. JAMA Netw Open. 2025 May 01; 8(5):e258903.
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Cardiovascular Health and Biomarkers of Neurodegenerative Disease in Older Adults. JAMA Netw Open. 2025 Mar 03; 8(3):e250527.
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Association of subjective memory complaints with serum biomarkers of neurodegeneration and cognition: A population-based study. J Am Geriatr Soc. 2025 Mar; 73(3):859-866.
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Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease. Neurobiol Aging. 2020 09; 93:61-68.
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Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 01; 135(1):85-93.
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Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of?Selective Neuronal Vulnerability. Stem Cell Reports. 2017 12 12; 9(6):1868-1884.
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Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology. J Alzheimers Dis. 2017; 56(2):699-706.
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?-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and ?-amyloid accumulation. Eur J Neurosci. 2010 Oct; 32(7):1223-38.