"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
| Descriptor ID |
D016875
|
| MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
| Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 4 | 5 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 3 | 5 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 2 | 4 |
| 2015 | 4 | 2 | 6 |
| 2016 | 3 | 1 | 4 |
| 2017 | 3 | 5 | 8 |
| 2018 | 5 | 5 | 10 |
| 2019 | 5 | 2 | 7 |
| 2020 | 3 | 2 | 5 |
| 2021 | 3 | 6 | 9 |
| 2022 | 0 | 8 | 8 |
| 2023 | 0 | 11 | 11 |
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Below are the most recent publications written about "tau Proteins" by people in Profiles.
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Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease. Nat Commun. 2023 Nov 30; 14(1):7659.
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Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models. J Clin Invest. 2023 09 15; 133(18).
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Age-related and amyloid-beta-independent tau deposition and its downstream effects. Brain. 2023 08 01; 146(8):3192-3205.
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When Alzheimer's is LATE: Why Does it Matter? Ann Neurol. 2023 08; 94(2):211-222.
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Unconventional Source of Neurotoxic Protein Aggregation from Organelle Off-Target Bax?2 in Alzheimer's Disease. Biomolecules. 2023 06 10; 13(6).
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Cognitive Activity Is Associated with Cognitive Function over Time in a Diverse Group of Older Adults, Independent of Baseline Biomarkers. Neuroepidemiology. 2023; 57(4):229-237.
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Sex Differences in Alzheimer's Disease. Neurol Clin. 2023 05; 41(2):343-358.
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Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults. Acta Neuropathol. 2023 07; 146(1):1-11.
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Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease. Neurology. 2023 04 04; 100(14):e1474-e1487.
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Mixed pathology as a rule, not exception: Time to reconsider disease nosology. Handb Clin Neurol. 2023; 192:57-71.