"Cell Line, Transformed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eukaryotic cell line obtained in a quiescent or stationary phase which undergoes conversion to a state of unregulated growth in culture, resembling an in vitro tumor. It occurs spontaneously or through interaction with viruses, oncogenes, radiation, or drugs/chemicals.
| Descriptor ID |
D002461
|
| MeSH Number(s) |
A11.251.210.172
|
| Concept/Terms |
Cell Line, Transformed- Cell Line, Transformed
- Transformed Cell Line
- Cell Lines, Transformed
- Transformed Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "Cell Line, Transformed".
Below are MeSH descriptors whose meaning is more specific than "Cell Line, Transformed".
This graph shows the total number of publications written about "Cell Line, Transformed" by people in this website by year, and whether "Cell Line, Transformed" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cell Line, Transformed" by people in Profiles.
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Rho-Associated Kinase Inhibitor Immortalizes Rat Nucleus Pulposus and Annulus Fibrosus Cells: Establishment of Intervertebral Disc Cell Lines With Novel Approaches. Spine (Phila Pa 1976). 2016 Mar; 41(5):E255-61.
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Generation and preliminary characterization of immortalized cell line derived from rat lymphatic capillaries. Microcirculation. 2014 Aug; 21(6):551-61.
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Cerebrospinal fluid tau cleaved by caspase-6 reflects brain levels and cognition in aging and Alzheimer disease. J Neuropathol Exp Neurol. 2013 Sep; 72(9):824-32.
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Glucocorticoid receptor activation inhibits p53-induced apoptosis of MCF10Amyc cells via induction of protein kinase Ce. J Biol Chem. 2012 Aug 24; 287(35):29825-36.
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Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis. 2012; 28(2):433-41.
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Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture. J Biol Chem. 2010 Jan 08; 285(2):1555-68.
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Focal adhesion components are essential for mammalian cell cytokinesis. Cell Cycle. 2008 Sep 15; 7(18):2868-76.
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Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors. J Biol Chem. 2008 Oct 10; 283(41):27585-27597.
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Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis. Pharmacogenet Genomics. 2008 Mar; 18(3):253-62.
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Benzo[a]pyrene-7,8-diol-9,10-epoxide causes caspase-mediated apoptosis in H460 human lung cancer cell line. Cell Cycle. 2007 Nov 15; 6(22):2826-34.