 Leupeptins
"Leupeptins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins.
| Descriptor ID |
D007976
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| MeSH Number(s) |
D12.644.456.580
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Leupeptins".
Below are MeSH descriptors whose meaning is more specific than "Leupeptins".
This graph shows the total number of publications written about "Leupeptins" by people in this website by year, and whether "Leupeptins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leupeptins" by people in Profiles.
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Contaldo C, Myers TJ, Zucchini C, Manara MC, Chiodoni C, Colombo MP, Nicoletti G, Lollini PL, Li T, Longobardi L, Scotlandi K, Spagnoli A. Expression levels of insulin receptor substrate-1 modulate the osteoblastic differentiation of mesenchymal stem cells and osteosarcoma cells. Growth Factors. 2014 Feb; 32(1):41-52.
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Miller BT, Ueta CB, Lau V, Jacomino KG, Wasserman LM, Kim BW. Statins and downstream inhibitors of the isoprenylation pathway increase type 2 iodothyronine deiodinase activity. Endocrinology. 2012 Aug; 153(8):4039-48.
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Zhang L, Nie L, Maki CG. P53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity. Mol Cancer. 2006 Dec 06; 5:68.
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Maki CG, Huibregtse JM, Howley PM. In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res. 1996 Jun 01; 56(11):2649-54.
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