David Williams to Animals
This is a "connection" page, showing publications David Williams has written about Animals.
Connection Strength
1.395
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Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. ACS Infect Dis. 2020 03 13; 6(3):393-405.
Score: 0.095
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The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004279.
Score: 0.072
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Characterization of potential drug targets farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase in Schistosoma mansoni. Antimicrob Agents Chemother. 2013 Dec; 57(12):5969-76.
Score: 0.061
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Characterization of the phytochelatin synthase from the human parasitic nematode Ancylostoma ceylanicum. Mol Biochem Parasitol. 2013 Sep; 191(1):1-6.
Score: 0.061
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Towards an understanding of the function of the phytochelatin synthase of Schistosoma mansoni. PLoS Negl Trop Dis. 2013; 7(1):e2037.
Score: 0.059
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Transcriptional analysis of a unique set of genes involved in Schistosoma mansoni female reproductive biology. PLoS Negl Trop Dis. 2012; 6(11):e1907.
Score: 0.058
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Thioredoxin glutathione reductase-dependent redox networks in platyhelminth parasites. Antioxid Redox Signal. 2013 Sep 01; 19(7):735-45.
Score: 0.057
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The redox biology of schistosome parasites and applications for drug development. Curr Pharm Des. 2012; 18(24):3595-611.
Score: 0.054
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Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni. Biochemistry. 2011 Jul 05; 50(26):5870-82.
Score: 0.052
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Characterization of the phytochelatin synthase of Schistosoma mansoni. PLoS Negl Trop Dis. 2011 May; 5(5):e1168.
Score: 0.052
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Whole mount in situ hybridization methodology for Schistosoma mansoni. Mol Biochem Parasitol. 2011 Jul-Aug; 178(1-2):46-50.
Score: 0.052
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Characterization of the methionine sulfoxide reductases of Schistosoma mansoni. J Parasitol. 2009 Dec; 95(6):1421-8.
Score: 0.047
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Identification of oxadiazoles as new drug leads for the control of schistosomiasis. Nat Med. 2008 Apr; 14(4):407-12.
Score: 0.042
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Proteomic analysis of Schistosoma mansoni egg secretions. Mol Biochem Parasitol. 2007 Oct; 155(2):84-93.
Score: 0.040
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Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. PLoS Med. 2007 Jun; 4(6):e206.
Score: 0.040
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Profiling Schistosoma mansoni development using serial analysis of gene expression (SAGE). Exp Parasitol. 2007 Nov; 117(3):246-58.
Score: 0.039
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Schistosoma mansoni albumin, a major defense against oxidative damage, was acquired by lateral gene transfer from a mammalian host. Mol Biochem Parasitol. 2006 Dec; 150(2):359-63.
Score: 0.037
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Redox balance mechanisms in Schistosoma mansoni rely on peroxiredoxins and albumin and implicate peroxiredoxins as novel drug targets. J Biol Chem. 2006 Jun 23; 281(25):17001-17010.
Score: 0.037
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Murine immune responses to a novel schistosome egg antigen, SmEP25. Int J Parasitol. 2005 Jul; 35(8):875-82.
Score: 0.035
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Biochemical characterization of 2-Cys peroxiredoxins from Schistosoma mansoni. J Biol Chem. 2004 Jun 18; 279(25):26159-66.
Score: 0.032
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Characterisation of a Rho homologue of Schistosoma mansoni. Int J Parasitol. 2003 Jul; 33(7):721-31.
Score: 0.030
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Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo. Nat Commun. 2023 06 22; 14(1):3737.
Score: 0.030
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Descriptive Analysis of Transient-State Observations for Thioredoxin/Glutathione Reductase (Sec597Cys) from Schistosoma mansoni. Biochemistry. 2023 05 02; 62(9):1497-1508.
Score: 0.030
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Adenylosuccinate lyase of Schistosoma mansoni: gene structure, mRNA expression, and analysis of the predicted peptide structure of a potential chemotherapeutic target. Int J Parasitol. 2002 Nov; 32(12):1487-95.
Score: 0.029
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Molecular and enzymatic characterisation of Schistosoma mansoni thioredoxin. Int J Parasitol. 2002 Sep; 32(10):1285-92.
Score: 0.028
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The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase. Mol Biochem Parasitol. 2002 Apr 30; 121(1):129-39.
Score: 0.028
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An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity. Cell. 2022 02 17; 185(4):614-629.e21.
Score: 0.027
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Schistosome infection stimulates host CD4(+) T helper cell and B-cell responses against a novel egg antigen, thioredoxin peroxidase. Infect Immun. 2001 Feb; 69(2):1134-41.
Score: 0.026
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Molecular and enzymatic characterization of Schistosoma mansoni thioredoxin peroxidase. J Parasitol. 2000 Oct; 86(5):908-15.
Score: 0.025
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Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med. 2020 02 01; 147:200-211.
Score: 0.024
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Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. 2019 11 19; 51(5):899-914.e7.
Score: 0.023
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High-throughput screening against thioredoxin glutathione reductase identifies novel inhibitors with potential therapeutic value for schistosomiasis. Infect Dis Poverty. 2015 Aug 31; 4:40.
Score: 0.018
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Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis. PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003534.
Score: 0.017
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Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. Structure. 2012 Mar 07; 20(3):429-39.
Score: 0.014
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An atlas for Schistosoma mansoni organs and life-cycle stages using cell type-specific markers and confocal microscopy. PLoS Negl Trop Dis. 2011 Mar 08; 5(3):e1009.
Score: 0.013
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Differential production in vitro of antigen specific IgG1, IgG3 and IgA: a study in Schistosoma haematobium infected individuals. Parasite Immunol. 2003 Jan; 25(1):39-44.
Score: 0.007
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Construction and characterization of a Schistosoma mansoni bacterial artificial chromosome library. Genomics. 2000 Apr 15; 65(2):87-94.
Score: 0.006