 Free Radicals
"Free Radicals" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
| Descriptor ID |
D005609
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| MeSH Number(s) |
D01.339 D02.389
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Free Radicals".
Below are MeSH descriptors whose meaning is more specific than "Free Radicals".
This graph shows the total number of publications written about "Free Radicals" by people in this website by year, and whether "Free Radicals" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1999 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Free Radicals" by people in Profiles.
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Gallardo LA, Knowlton CB, Kunze J, Jacobs JJ, Wimmer MA, Laurent MP. Effect of europium(II) stearate on the mechanical properties and the oxidation resistance of UHMWPE. J Mech Behav Biomed Mater. 2011 Jul; 4(5):821-6.
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Zaheer A, Sahu SK, Ryken TC, Traynelis VC. Cis-parinaric acid effects, cytotoxicity, c-Jun N-terminal protein kinase, forkhead transcription factor and Mn-SOD differentially in malignant and normal astrocytes. Neurochem Res. 2007 Jan; 32(1):115-24.
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Keshavarzian A, Banan A, Farhadi A, Komanduri S, Mutlu E, Zhang Y, Fields JZ. Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease. Gut. 2003 May; 52(5):720-8.
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Anderson KM, Ells G, Bonomi P, Harris JE. Free radical spin traps as adjuncts for the prevention and treatment of disease. Med Hypotheses. 1999 Jan; 52(1):53-7.
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Robinson CE, Keshavarzian A, Pasco DS, Frommel TO, Winship DH, Holmes EW. Determination of protein carbonyl groups by immunoblotting. Anal Biochem. 1999 Jan 01; 266(1):48-57.
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Gaginella TS, Kachur JF, Tamai H, Keshavarzian A. Reactive oxygen and nitrogen metabolites as mediators of secretory diarrhea. Gastroenterology. 1995 Dec; 109(6):2019-28.
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Arterbery VE, Pryor WA, Jiang L, Sehnert SS, Foster WM, Abrams RA, Williams JR, Wharam MD, Risby TH. Breath ethane generation during clinical total body irradiation as a marker of oxygen-free-radical-mediated lipid peroxidation: a case study. Free Radic Biol Med. 1994 Dec; 17(6):569-76.
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Keshavarzian A, Morgan G, Sedghi S, Gordon JH, Doria M. Role of reactive oxygen metabolites in experimental colitis. Gut. 1990 Jul; 31(7):786-90.
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