 Complement Activation
"Complement Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequential activation of serum COMPLEMENT PROTEINS to create the COMPLEMENT MEMBRANE ATTACK COMPLEX. Factors initiating complement activation include ANTIGEN-ANTIBODY COMPLEXES, microbial ANTIGENS, or cell surface POLYSACCHARIDES.
| Descriptor ID |
D003167
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| MeSH Number(s) |
G12.425.255
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| Concept/Terms |
Complement Activation- Complement Activation
- Activation, Complement
- Activations, Complement
- Complement Activations
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Below are MeSH descriptors whose meaning is more general than "Complement Activation".
Below are MeSH descriptors whose meaning is more specific than "Complement Activation".
This graph shows the total number of publications written about "Complement Activation" by people in this website by year, and whether "Complement Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 2 | 0 | 2 | | 1995 | 1 | 1 | 2 | | 2010 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement Activation" by people in Profiles.
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Galili U, Goldufsky JW, Schaer GL. a-Gal Nanoparticles Mediated Homing of Endogenous Stem Cells for Repair and Regeneration of External and Internal Injuries by Localized Complement Activation and Macrophage Recruitment. Int J Mol Sci. 2022 Sep 29; 23(19).
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Adeniji OS, Giron LB, Purwar M, Zilberstein NF, Kulkarni AJ, Shaikh MW, Balk RA, Moy JN, Forsyth CB, Liu Q, Dweep H, Kossenkov A, Weiner DB, Keshavarzian A, Landay A, Abdel-Mohsen M. COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions. mBio. 2021 04 20; 12(2).
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van Poll D, Nahmias Y, Soto-Gutierrez A, Ghasemi M, Yagi H, Kobayashi N, Yarmush ML, Hertl M. Human immune reactivity against liver sinusoidal endothelial cells from GalTa(1,3)GalT-deficient pigs. Cell Transplant. 2010; 19(6):783-9.
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Hauser PV, Pippin JW, Kaiser C, Krofft RD, Brinkkoetter PT, Hudkins KL, Kerjaschki D, Reiser J, Alpers CE, Shankland SJ. Novel siRNA delivery system to target podocytes in vivo. PLoS One. 2010 Mar 01; 5(3):e9463.
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Ji X, Gewurz H, Spear GT. Mannose binding lectin (MBL) and HIV. Mol Immunol. 2005 Feb; 42(2):145-52.
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Siegal FP, Spear GT. Innate immunity and HIV. AIDS. 2001; 15 Suppl 5:S127-37.
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Sullivan BL, Takefman DM, Spear GT. Complement can neutralize HIV-1 plasma virus by a C5-independent mechanism. Virology. 1998 Sep 01; 248(2):173-81.
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Sereti I, Spear GT. Complement activation by HIV-1-infected target cells enhances IL-2-stimulated but not unstimulated ADCC activity mediated by peripheral blood mononuclear cells. Clin Immunol Immunopathol. 1996 Jan; 78(1):77-82.
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Saifuddin M, Landay AL, Ghassemi M, Patki C, Spear GT. HTLV-I activates complement leading to increased binding to complement receptor-positive cells. AIDS Res Hum Retroviruses. 1995 Sep; 11(9):1115-22.
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Saifuddin M, Parker CJ, Peeples ME, Gorny MK, Zolla-Pazner S, Ghassemi M, Rooney IA, Atkinson JP, Spear GT. Role of virion-associated glycosylphosphatidylinositol-linked proteins CD55 and CD59 in complement resistance of cell line-derived and primary isolates of HIV-1. J Exp Med. 1995 Aug 01; 182(2):501-9.
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