"Genes, myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
| Descriptor ID |
D016259
|
| MeSH Number(s) |
G05.360.340.024.340.375.500.791.420
|
| Concept/Terms |
c-myc Genes- c-myc Genes
- Gene, c-myc
- Genes, c-myc
- c myc Genes
- c-myc Gene
c-myc Proto-Oncogenes- c-myc Proto-Oncogenes
- Proto-Oncogene, c-myc
- Proto-Oncogenes, c-myc
- c myc Proto Oncogenes
- c-myc Proto-Oncogene
v-myc Genes- v-myc Genes
- Gene, v-myc
- Genes, v-myc
- v myc Genes
- v-myc Gene
L-myc Proto-Oncogenes- L-myc Proto-Oncogenes
- L myc Proto Oncogenes
- L-myc Proto-Oncogene
- Proto-Oncogene, L-myc
- Proto-Oncogenes, L-myc
myc Oncogene- myc Oncogene
- Oncogene, myc
- Oncogenes, myc
- myc Oncogenes
N-myc Genes- N-myc Genes
- Gene, N-myc
- Genes, N-myc
- N myc Genes
- N-myc Gene
N-myc Proto-Oncogenes- N-myc Proto-Oncogenes
- N myc Proto Oncogenes
- N-myc Proto-Oncogene
- Proto-Oncogene, N-myc
- Proto-Oncogenes, N-myc
v-myc Oncogenes- v-myc Oncogenes
- Oncogene, v-myc
- Oncogenes, v-myc
- v myc Oncogenes
- v-myc Oncogene
L-myc Genes- L-myc Genes
- Gene, L-myc
- Genes, L-myc
- L myc Genes
- L-myc Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, myc".
Below are MeSH descriptors whose meaning is more specific than "Genes, myc".
This graph shows the total number of publications written about "Genes, myc" by people in this website by year, and whether "Genes, myc" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, myc" by people in Profiles.
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C-MYC-positive relapsed and refractory, diffuse large B-cell lymphoma: Impact of additional "hits" and outcomes with subsequent therapy. Cancer. 2017 11 15; 123(22):4411-4418.
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Sole rearrangement but not amplification of MYC is associated with a poor prognosis in patients with diffuse large B cell lymphoma and B cell lymphoma unclassifiable. Br J Haematol. 2016 Nov; 175(4):631-640.
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Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma. Int J Oncol. 2011 Jan; 38(1):105-12.
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MYC amplification in breast cancer: a chromogenic in situ hybridisation study. J Clin Pathol. 2007 Sep; 60(9):1017-23.
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Early gene response to low-intensity pulsed ultrasound in rat osteoblastic cells. Ultrasound Med Biol. 2005 May; 31(5):703-8.
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Pathobiology of hemophilic synovitis I: overexpression of mdm2 oncogene. Blood. 2004 Oct 01; 104(7):2060-4.
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Antibody-induced shedding of CD44 from adherent cells is linked to the assembly of the cytoskeleton. J Immunol. 2001 Jul 01; 167(1):123-31.