 Neutrophil Activation
"Neutrophil Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonized particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil.
| Descriptor ID |
D018375
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| MeSH Number(s) |
G12.425.897
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| Concept/Terms |
Neutrophil Activation- Neutrophil Activation
- Activation, Neutrophil
- Activations, Neutrophil
- Neutrophil Activations
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Below are MeSH descriptors whose meaning is more general than "Neutrophil Activation".
Below are MeSH descriptors whose meaning is more specific than "Neutrophil Activation".
This graph shows the total number of publications written about "Neutrophil Activation" by people in this website by year, and whether "Neutrophil Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neutrophil Activation" by people in Profiles.
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Wargodsky R, Dela Cruz P, LaFleur J, Yamane D, Kim JS, Benjenk I, Heinz E, Irondi OO, Farrar K, Toma I, Jordan T, Goldman J, McCaffrey TA. RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections. PLoS One. 2022; 17(1):e0261679.
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Albrengues J, Wysocki RW, Maiorino L, Egeblad M. Re-cyclin' Cell-Cycle Components to Make NETs. Dev Cell. 2017 11 20; 43(4):379-380.
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Noss I, Ozment TR, Graves BM, Kruppa MD, Rice PJ, Williams DL. Cellular and molecular mechanisms of fungal ß-(1?6)-glucan in macrophages. Innate Immun. 2015 Oct; 21(7):759-69.
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Fu J, Sha BE, Thomas LL. HIV-1-infected peripheral blood mononuclear cells enhance neutrophil survival and HLA-DR expression via increased production of GM-CSF: implications for HIV-1 infection. J Acquir Immune Defic Syndr. 2011 Jan 01; 56(1):16-25.
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Gabali AM, Anzinger JJ, Spear GT, Thomas LL. Activation by inflammatory stimuli increases neutrophil binding of human immunodeficiency virus type 1 and subsequent infection of lymphocytes. J Virol. 2004 Oct; 78(19):10833-6.
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Keshavarzian A, Fusunyan RD, Jacyno M, Winship D, MacDermott RP, Sanderson IR. Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: evidence for a biological role for IL-8 in inflammation of the colon. Am J Gastroenterol. 1999 Mar; 94(3):704-12.
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Robinson CE, Kottapalli V, D'Astice M, Fields JZ, Winship D, Keshavarzian A. Regulation of neutrophils in ulcerative colitis by colonic factors: a possible mechanism of neutrophil activation and tissue damage. J Lab Clin Med. 1997 Dec; 130(6):590-602.
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Patel M, Keshavarzian A, Kottapalli V, Badie B, Winship D, Fields JZ. Human neutrophil functions are inhibited in vitro by clinically relevant ethanol concentrations. Alcohol Clin Exp Res. 1996 Apr; 20(2):275-83.
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