Profiles

Keywords
Last Name
Institution

Mice, SCID

"Mice, SCID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

expand / collapse MeSH information
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.


expand / collapse publications
This graph shows the total number of publications written about "Mice, SCID" by people in this website by year, and whether "Mice, SCID" was a major or minor topic of these publications.
Bar chart showing 39 publications over 18 distinct years, with a maximum of 5 publications in 2006
To see the data from this visualization as text, click here.