"Claudin-5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
| Descriptor ID |
D062507
|
| MeSH Number(s) |
D12.776.543.940.200.500
|
| Concept/Terms |
Claudin-5- Claudin-5
- Transmembrane Protein Deleted in Velocardiofacial Syndrome
- TMVCF Protein
- Claudin 5
|
Below are MeSH descriptors whose meaning is more general than "Claudin-5".
Below are MeSH descriptors whose meaning is more specific than "Claudin-5".
This graph shows the total number of publications written about "Claudin-5" by people in this website by year, and whether "Claudin-5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Claudin-5" by people in Profiles.
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Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline. Biol Psychiatry. 2022 02 15; 91(4):389-398.
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Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63.
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Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown. Acta Neuropathol. 2007 Nov; 114(5):459-69.