"Tauopathies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.
| Descriptor ID |
D024801
|
| MeSH Number(s) |
C10.574.945
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tauopathies".
Below are MeSH descriptors whose meaning is more specific than "Tauopathies".
This graph shows the total number of publications written about "Tauopathies" by people in this website by year, and whether "Tauopathies" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 3 | 0 | 3 |
| 2017 | 1 | 1 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tauopathies" by people in Profiles.
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Age-related and amyloid-beta-independent tau deposition and its downstream effects. Brain. 2023 08 01; 146(8):3192-3205.
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Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies. Autophagy. 2023 02; 19(2):660-677.
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Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2022 01; 143(1):33-53.
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Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. J Neuropathol Exp Neurol. 2021 01 20; 80(2):102-111.
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Outcomes after diagnosis of mild cognitive impairment in a large autopsy series. Ann Neurol. 2017 Apr; 81(4):549-559.
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Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Mol Psychiatry. 2018 06; 23(6):1521-1529.
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Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathol. 2016 Jan; 131(1):87-102.
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miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo. Hum Mol Genet. 2015 Dec 01; 24(23):6721-35.
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PART, a distinct tauopathy, different from classical sporadic Alzheimer disease. Acta Neuropathol. 2015 May; 129(5):757-62.
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Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol. 2014 Dec; 128(6):755-66.