 Glycosaminoglycans
"Glycosaminoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine.
| Descriptor ID |
D006025
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| MeSH Number(s) |
D09.698.373
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycosaminoglycans".
Below are MeSH descriptors whose meaning is more specific than "Glycosaminoglycans".
This graph shows the total number of publications written about "Glycosaminoglycans" by people in this website by year, and whether "Glycosaminoglycans" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 0 | 1 | 1 | | 1984 | 1 | 0 | 1 | | 1985 | 0 | 1 | 1 | | 1986 | 0 | 3 | 3 | | 1989 | 3 | 0 | 3 | | 1990 | 1 | 1 | 2 | | 1991 | 1 | 1 | 2 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 3 | 3 | | 1995 | 1 | 1 | 2 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 0 | 2 | | 1999 | 1 | 0 | 1 | | 2000 | 0 | 3 | 3 | | 2001 | 3 | 0 | 3 | | 2002 | 0 | 2 | 2 | | 2003 | 2 | 1 | 3 | | 2005 | 2 | 2 | 4 | | 2006 | 1 | 0 | 1 | | 2009 | 0 | 3 | 3 | | 2010 | 1 | 2 | 3 | | 2011 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycosaminoglycans" by people in Profiles.
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Chan DD, Li J, Luo W, Predescu DN, Cole BJ, Plaas A. Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury. J Orthop Res. 2018 01; 36(1):365-376.
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Lam CH, Romanova L, Hubel A, Janson C, Hansen EA. The influence of fibroblast on the arachnoid leptomeningeal cells in vitro. Brain Res. 2017 02 15; 1657:109-119.
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Li Y, Frank EH, Wang Y, Chubinskaya S, Huang HH, Grodzinsky AJ. Moderate dynamic compression inhibits pro-catabolic response of cartilage to mechanical injury, tumor necrosis factor-a and interleukin-6, but accentuates degradation above a strain threshold. Osteoarthritis Cartilage. 2013 Dec; 21(12):1933-41.
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Miller RE, Kopesky PW, Grodzinsky AJ. Growth factor delivery through self-assembling peptide scaffolds. Clin Orthop Relat Res. 2011 Oct; 469(10):2716-24.
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Ghassemi-Nejad S, Kobezda T, Rauch TA, Matesz C, Glant TT, Mikecz K. Osteoarthritis-like damage of cartilage in the temporomandibular joints in mice with autoimmune inflammatory arthritis. Osteoarthritis Cartilage. 2011 Apr; 19(4):458-65.
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Rolauffs B, Muehleman C, Li J, Kurz B, Kuettner KE, Frank E, Grodzinsky AJ. Vulnerability of the superficial zone of immature articular cartilage to compressive injury. Arthritis Rheum. 2010 Oct; 62(10):3016-27.
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Lee HY, Kopesky PW, Plaas A, Sandy J, Kisiday J, Frisbie D, Grodzinsky AJ, Ortiz C. Adult bone marrow stromal cell-based tissue-engineered aggrecan exhibits ultrastructure and nanomechanical properties superior to native cartilage. Osteoarthritis Cartilage. 2010 Nov; 18(11):1477-86.
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Byun S, Tortorella MD, Malfait AM, Fok K, Frank EH, Grodzinsky AJ. Transport and equilibrium uptake of a peptide inhibitor of PACE4 into articular cartilage is dominated by electrostatic interactions. Arch Biochem Biophys. 2010 Jul; 499(1-2):32-9.
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Lemke AK, Sandy JD, Voigt H, Dreier R, Lee JH, Grodzinsky AJ, Mentlein R, Fay J, Schünke M, Kurz B. Interleukin-1alpha treatment of meniscal explants stimulates the production and release of aggrecanase-generated, GAG-substituted aggrecan products and also the release of pre-formed, aggrecanase-generated G1 and m-calpain-generated G1-G2. Cell Tissue Res. 2010 Apr; 340(1):179-88.
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Wilson CG, Vanderploeg EJ, Zuo F, Sandy JD, Levenston ME. Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. Arthritis Res Ther. 2009; 11(6):R173.
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