 Virus Latency
"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.
| Descriptor ID |
D017735
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| MeSH Number(s) |
G06.920.900
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| Concept/Terms |
Virus Latency- Virus Latency
- Latencies, Virus
- Latency, Virus
- Virus Latencies
- Viral Latency
- Latencies, Viral
- Latency, Viral
- Viral Latencies
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Below are MeSH descriptors whose meaning is more general than "Virus Latency".
Below are MeSH descriptors whose meaning is more specific than "Virus Latency".
This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Virus Latency" by people in Profiles.
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Barbian HJ, Seaton MS, Narasipura SD, Wallace J, Rajan R, Sha BE, Al-Harthi L. ?-catenin regulates HIV latency and modulates HIV reactivation. PLoS Pathog. 2022 03; 18(3):e1010354.
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Giron LB, Papasavvas E, Yin X, Goldman AR, Tang HY, Palmer CS, Landay AL, Li JZ, Koethe JR, Mounzer K, Kostman JR, Liu Q, Montaner LJ, Abdel-Mohsen M. Phospholipid Metabolism Is Associated with Time to HIV Rebound upon Treatment Interruption. mBio. 2021 02 23; 12(1).
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Narasipura SD, Kim S, Al-Harthi L. Epigenetic regulation of HIV-1 latency in astrocytes. J Virol. 2014 Mar; 88(5):3031-8.
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Towards an HIV cure: a global scientific strategy. Nat Rev Immunol. 2012 07 20; 12(8):607-14.
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Al-Harthi L, Kashanchi F. Mechanisms of HIV-1 latency post HAART treatment area. Curr HIV Res. 2011 Dec 01; 9(8):552-3.
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Imamichi H, Degray G, Asmuth DM, Fischl MA, Landay AL, Lederman MM, Sereti I. HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy. AIDS. 2011 Jan 14; 25(2):159-64.
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Tan CS, Ellis LC, W?thrich C, Ngo L, Broge TA, Saint-Aubyn J, Miller JS, Koralnik IJ. JC virus latency in the brain and extraneural organs of patients with and without progressive multifocal leukoencephalopathy. J Virol. 2010 Sep; 84(18):9200-9.
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Tan CS, Dezube BJ, Bhargava P, Autissier P, W?thrich C, Miller J, Koralnik IJ. Detection of JC virus DNA and proteins in the bone marrow of HIV-positive and HIV-negative patients: implications for viral latency and neurotropic transformation. J Infect Dis. 2009 Mar 15; 199(6):881-8.
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Kumar A, Zloza A, Moon RT, Watts J, Tenorio AR, Al-Harthi L. Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol. 2008 Mar; 82(6):2813-20.
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Rabbi MF, al-Harthi L, Saifuddin M, Roebuck KA. The cAMP-dependent protein kinase A and protein kinase C-beta pathways synergistically interact to activate HIV-1 transcription in latently infected cells of monocyte/macrophage lineage. Virology. 1998 Jun 05; 245(2):257-69.
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