"Lipoxygenase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that bind to and inhibit that enzymatic activity of LIPOXYGENASES. Included under this category are inhibitors that are specific for lipoxygenase subtypes and act to reduce the production of LEUKOTRIENES.
| Descriptor ID |
D016859
|
| MeSH Number(s) |
D27.505.519.389.480
|
| Concept/Terms |
Arachidonate 15-Lipoxygenase Inhibitors- Arachidonate 15-Lipoxygenase Inhibitors
- 15-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 15 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 15-Lipoxygenase
- 15-Lipoxygenase Inhibitors
- 15 Lipoxygenase Inhibitors
- Inhibitors, 15-Lipoxygenase
Arachidonate 5-Lipoxygenase Inhibitors- Arachidonate 5-Lipoxygenase Inhibitors
- 5-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 5 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 5-Lipoxygenase
- 5-Lipoxygenase Inhibitors
- 5 Lipoxygenase Inhibitors
- Inhibitors, 5-Lipoxygenase
Arachidonate 12-Lipoxygenase Inhibitors- Arachidonate 12-Lipoxygenase Inhibitors
- 12-Lipoxygenase Inhibitors, Arachidonate
- Arachidonate 12 Lipoxygenase Inhibitors
- Inhibitors, Arachidonate 12-Lipoxygenase
- 12-Lipoxygenase Inhibitors
- 12 Lipoxygenase Inhibitors
- Inhibitors, 12-Lipoxygenase
|
Below are MeSH descriptors whose meaning is more general than "Lipoxygenase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Lipoxygenase Inhibitors".
This graph shows the total number of publications written about "Lipoxygenase Inhibitors" by people in this website by year, and whether "Lipoxygenase Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lipoxygenase Inhibitors" by people in Profiles.
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Ingenuity network-assisted transcription profiling: Identification of a new pharmacologic mechanism for MK886. Clin Cancer Res. 2006 Mar 15; 12(6):1820-7.
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Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions. FASEB J. 2001 Sep; 15(11):2007-9.
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Relationship of arachidonic acid metabolizing enzyme expression in epithelial cancer cell lines to the growth effect of selective biochemical inhibitors. Cancer Res. 1999 May 01; 59(9):2223-8.
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5-Lipoxygenase inhibitors reduce PC-3 cell proliferation and initiate nonnecrotic cell death. Prostate. 1998 Nov 01; 37(3):161-73.
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Lipoxygenase inhibitors prevent lung carcinogenesis and inhibit non-small cell lung cancer growth. Exp Lung Res. 1998 Jul-Aug; 24(4):617-28.
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The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats. Inflammation. 1996 Jun; 20(3):217-27.
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Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling. J Clin Invest. 1996 Feb 01; 97(3):806-13.