"Bombesin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It is also an endogenous neurotransmitter in many animals including mammals. Bombesin affects vascular and other smooth muscle, gastric secretion, and renal circulation and function.
| Descriptor ID |
D001839
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| MeSH Number(s) |
D06.472.699.100 D12.644.400.085 D12.644.548.100 D12.776.631.650.085 D20.888.033.137 D23.946.833.033.137
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bombesin".
Below are MeSH descriptors whose meaning is more specific than "Bombesin".
This graph shows the total number of publications written about "Bombesin" by people in this website by year, and whether "Bombesin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bombesin" by people in Profiles.
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Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer. Chest. 1997 Jul; 112(1):256-61.
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Effect of gastrin-releasing peptide on the pancreatic tumor cell line (Capan). Mol Carcinog. 1993; 8(4):214-20.
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Preclinical evaluation of an anti-autocrine growth factor monoclonal antibody for treatment of patients with small-cell lung cancer. J Natl Cancer Inst. 1991 Oct 16; 83(20):1470-6.
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[Psi 13,14] bombesin analogues inhibit growth of small cell lung cancerin vitro and in vivo. Cancer Res. 1991 Apr 01; 51(7):1798-802.
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Autocrine growth factors as therapeutic targets in lung cancer. Chest. 1989 Jul; 96(1 Suppl):31S-34S.
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A novel bombesin receptor antagonist inhibits autocrine signals in a small cell lung carcinoma cell line. Biochem Biophys Res Commun. 1988 Nov 15; 156(3):1383-9.
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Clinical use of a monoclonal antibody to bombesin-like peptide in patients with lung cancer. Ann N Y Acad Sci. 1988; 547:360-72.
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Consideration of the chemistry of solid-phase matrix interaction leads to improved quantitation of neuropeptides. Ann N Y Acad Sci. 1988; 547:41-53.
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Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature. 1985 Aug 29-Sep 4; 316(6031):823-6.
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Autocrine growth factors in human small cell lung cancer. Cancer Surv. 1985; 4(4):707-27.