 Lymphocyte Activation
"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
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| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.425.747 G12.450.050.400.545
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| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blastogenesis
- Lymphoblast Transformation
- Transformation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Blast
- Transformation, Lymphoblast
- Blast Transformation
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
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Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1983 | 1 | 1 | 2 | | 1984 | 3 | 0 | 3 | | 1985 | 0 | 3 | 3 | | 1986 | 0 | 2 | 2 | | 1987 | 2 | 1 | 3 | | 1988 | 1 | 2 | 3 | | 1989 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1991 | 1 | 2 | 3 | | 1992 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 3 | 4 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 4 | 5 | | 1998 | 0 | 5 | 5 | | 1999 | 0 | 4 | 4 | | 2000 | 2 | 5 | 7 | | 2001 | 2 | 4 | 6 | | 2002 | 3 | 5 | 8 | | 2003 | 3 | 2 | 5 | | 2004 | 5 | 3 | 8 | | 2005 | 3 | 3 | 6 | | 2006 | 2 | 6 | 8 | | 2007 | 0 | 4 | 4 | | 2008 | 2 | 2 | 4 | | 2009 | 1 | 2 | 3 | | 2010 | 3 | 4 | 7 | | 2011 | 3 | 2 | 5 | | 2012 | 4 | 4 | 8 | | 2013 | 5 | 6 | 11 | | 2014 | 5 | 3 | 8 | | 2015 | 0 | 2 | 2 | | 2016 | 1 | 3 | 4 | | 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Dillon SM, Castleman MJ, Frank DN, Austin GL, Gianella S, Cogswell AC, Landay AL, Barker E, Wilson CC. Brief Report: Inflammatory Colonic Innate Lymphoid Cells Are Increased During Untreated HIV-1 Infection and Associated With Markers of Gut Dysbiosis and Mucosal Immune Activation. J Acquir Immune Defic Syndr. 2017 12 01; 76(4):431-437.
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Dillon SM, Kibbie J, Lee EJ, Guo K, Santiago ML, Austin GL, Gianella S, Landay AL, Donovan AM, Frank DN, McCARTER MD, Wilson CC. Low abundance of colonic butyrate-producing bacteria in HIV infection is associated with microbial translocation and immune activation. AIDS. 2017 02 20; 31(4):511-521.
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Judge CJ, Sandberg JK, Funderburg NT, Sherman KE, Butt AA, Kang M, Landay AL, Lederman MM, Anthony DD. Brief Report: CD14brightCD16- monocytes and sCD14 level negatively associate with CD4-memory T-cell frequency and predict HCV-decline on therapy. J Acquir Immune Defic Syndr. 2016 11 01; 73(3):258-262.
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Boudreau JE, Mulrooney TJ, Le Luduec JB, Barker E, Hsu KC. KIR3DL1 and HLA-B Density and Binding Calibrate NK Education and Response to HIV. J Immunol. 2016 Apr 15; 196(8):3398-410.
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Spencer LY, Christiansen S, Wang CH, Mack WJ, Young M, Strickler HD, Anastos K, Minkoff H, Cohen M, Geenblatt RM, Karim R, Operskalski E, Frederick T, Homans JD, Landay A, Kovacs A. Systemic Immune Activation and HIV Shedding in the Female Genital Tract. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):155-62.
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Serrano-Villar S, Sainz T, Ma ZM, Utay NS, Chun TW, Wook-Chun T, Mann S, Kashuba AD, Siewe B, Albanese A, Troia-Cancio P, Sinclair E, Somasunderam A, Yotter T, Deeks SG, Landay A, Pollard RB, Miller CJ, Moreno S, Asmuth DM. Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog. 2016 Jan; 12(1):e1005381.
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Richards MH, Narasipura SD, Seaton MS, Lutgen V, Al-Harthi L. Migration of CD8+ T Cells into the Central Nervous System Gives Rise to Highly Potent Anti-HIV CD4dimCD8bright T Cells in a Wnt Signaling-Dependent Manner. J Immunol. 2016 Jan 01; 196(1):317-27.
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Dillon SM, Lee EJ, Kotter CV, Austin GL, Gianella S, Siewe B, Smith DM, Landay AL, McManus MC, Robertson CE, Frank DN, McCarter MD, Wilson CC. Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection. Mucosal Immunol. 2016 Jan; 9(1):24-37.
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Karim R, Mack WJ, Kono N, Tien PC, Anastos K, Lazar J, Young M, Desai S, Golub ET, Kaplan RC, Hodis HN, Kovacs A. T-cell activation, both pre- and post-HAART levels, correlates with carotid artery stiffness over 6.5 years among HIV-infected women in the WIHS. J Acquir Immune Defic Syndr. 2014 Nov 01; 67(3):349-56.
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Tenorio AR, Chan ES, Bosch RJ, Macatangay BJ, Read SW, Yesmin S, Taiwo B, Margolis DM, Jacobson JM, Landay AL, Wilson CC. Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy - ACTG A5286. J Infect Dis. 2015 Mar 01; 211(5):780-90.
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