"Notochord" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cartilaginous rod of mesodermal cells at the dorsal midline of all CHORDATE embryos. In lower vertebrates, notochord is the backbone of support. In the higher vertebrates, notochord is a transient structure, and segments of the vertebral column will develop around it. Notochord is also a source of midline signals that pattern surrounding tissues including the NEURAL TUBE development.
| Descriptor ID |
D009672
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| MeSH Number(s) |
A16.660
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Notochord".
Below are MeSH descriptors whose meaning is more specific than "Notochord".
This graph shows the total number of publications written about "Notochord" by people in this website by year, and whether "Notochord" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Notochord" by people in Profiles.
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Notochordal cells stimulate migration of cartilage end plate chondrocytes of the intervertebral disc in in vitro cell migration assays. Spine J. 2009 Apr; 9(4):323-9.
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The apoptotic effects of oxidative stress and antiapoptotic effects of caspase inhibitors on rat notochordal cells. Spine (Phila Pa 1976). 2007 Oct 15; 32(22):2443-8.
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Dynamic expression of the osmosensory channel trpv4 in multiple developing organs in zebrafish. Gene Expr Patterns. 2007 Feb; 7(4):480-4.
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An autocrine or paracrine Fas-mediated counterattack: a potential mechanism for apoptosis of notochordal cells in intact rat nucleus pulposus. Spine (Phila Pa 1976). 2005 Jun 01; 30(11):1247-51.
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The origin of chondrocytes in the nucleus pulposus and histologic findings associated with the transition of a notochordal nucleus pulposus to a fibrocartilaginous nucleus pulposus in intact rabbit intervertebral discs. Spine (Phila Pa 1976). 2003 May 15; 28(10):982-90.