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Malfait, Anne-Marie

One or more keywords matched the following items that are connected to Malfait, Anne-Marie

Item Type	Name
Concept	Osteoarthritis
Concept	Osteoarthritis, Knee
Academic Article	CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis.
Academic Article	ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).
Academic Article	The Role of Peripheral Nociceptive Neurons in the Pathophysiology of Osteoarthritis Pain.
Academic Article	Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4.
Academic Article	Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network.
Academic Article	A commentary on modelling osteoarthritis pain in small animals.
Academic Article	Synovial fluid from patients with early osteoarthritis modulates fibroblast-like synoviocyte responses to toll-like receptor 4 and toll-like receptor 2 ligands via soluble CD14.
Academic Article	Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models.
Academic Article	Modelling pain in post-traumatic osteoarthritis of the knee.
Academic Article	Towards a mechanism-based approach to pain management in osteoarthritis.
Academic Article	Osteoarthritis joint pain: the cytokine connection.
Academic Article	Identification of fibronectin neoepitopes present in human osteoarthritic cartilage.
Academic Article	Proprotein convertase activation of aggrecanases in cartilage in situ.
Academic Article	Nanoparticles for improved local retention after intra-articular injection into the knee joint.
Academic Article	A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.
Academic Article	Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5.
Academic Article	Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets.
Academic Article	The usual suspects: verdict not guilty?
Academic Article	On the predictive utility of animal models of osteoarthritis.
Academic Article	ADAMTS-5 deficient mice do not develop mechanical allodynia associated with osteoarthritis following medial meniscal destabilization.
Academic Article	Standardization of nutrient media for isolated human articular chondrocytes in gelified agarose suspension culture.
Academic Article	Will the real aggrecanase(s) step up: evaluating the criteria that define aggrecanase activity in osteoarthritis.
Academic Article	Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation.
Academic Article	Chemogenetic Inhibition of Pain Neurons in a Mouse Model of Osteoarthritis.
Academic Article	Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.
Academic Article	Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis.
Academic Article	Osteoarthritis year in review 2015: biology.
Academic Article	Spinal microglial activation in a murine surgical model of knee osteoarthritis.
Academic Article	Nerve growth factor blockade for the management of osteoarthritis pain: what can we learn from clinical trials and preclinical models?
Academic Article	Emerging Targets for the Management of Osteoarthritis Pain.
Academic Article	CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy.
Academic Article	Can we target CCR2 to treat osteoarthritis? The trick is in the timing!
Academic Article	Time to be positive about negative data?
Academic Article	Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis.
Academic Article	Current status of nerve growth factor antibodies for the treatment of osteoarthritis pain.
Academic Article	Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging.
Academic Article	What is new in pain modification in osteoarthritis?
Academic Article	Peripheral Mechanisms Contributing to Osteoarthritis Pain.
Academic Article	An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2.
Academic Article	Osteoarthritis pain: What are we learning from animal models?
Academic Article	Disease Burden in Osteoarthritis Is Similar to That of Rheumatoid Arthritis at Initial Rheumatology Visit and Significantly Greater Six Months Later.
Academic Article	Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety.
Academic Article	The nociceptive innervation of the normal and osteoarthritic mouse knee.
Academic Article	An emerging role for Toll-like receptors at the neuroimmune interface in osteoarthritis.
Academic Article	New concepts in osteoarthritis.
Academic Article	The "elusive DMOAD": Aggrecanase inhibition from laboratory to clinic.
Academic Article	The innate immune response as a mediator of osteoarthritis pain.
Academic Article	Why we should study osteoarthritis pain in experimental models in both sexes.
Academic Article	Microarray analyses of the dorsal root ganglia support a role for innate neuro-immune pathways in persistent pain in experimental osteoarthritis.
Academic Article	Targeting neurotrophic factors: Novel approaches to musculoskeletal pain.
Academic Article	Basic Mechanisms of Pain in Osteoarthritis: Experimental Observations and New Perspectives.
Academic Article	The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice.
Academic Article	Neuroimmune interactions and osteoarthritis pain: focus on macrophages.
Academic Article	Can we prevent chronic osteoarthritis pain? A view from the bench.
Academic Article	The Genesis of Pain in Osteoarthritis: Inflammation as a Mediator of Osteoarthritis Pain.
Academic Article	Doubling down on osteoarthritis: statement from the incoming editors-in-chief.
Academic Article	Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain.
Academic Article	Recommendations For a Standardized Approach to Histopathologic Evaluation of Synovial Membrane in Murine Models of Experimental Osteoarthritis.
Academic Article	Sexual dimorphism of the synovial transcriptome underpins greater PTOA disease severity in male mice following joint injury.
Academic Article	Age-Associated Changes in Knee Osteoarthritis, Pain-Related Behaviors, and Dorsal Root Ganglia Immunophenotyping of Male and Female Mice.
Academic Article	Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis.

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Osteoarthritis