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Search Results to Anne-Marie Malfait

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One or more keywords matched the following items that are connected to Malfait, Anne-Marie

Item TypeName
Concept Disease Models, Animal
Concept Animals
Concept Behavior, Animal
Concept Animals, Genetically Modified
Academic Article CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis.
Academic Article Structure analysis reveals the flexibility of the ADAMTS-5 active site.
Academic Article Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes.
Academic Article Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4.
Academic Article Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network.
Academic Article A commentary on modelling osteoarthritis pain in small animals.
Academic Article Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models.
Academic Article Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage.
Academic Article Modelling pain in post-traumatic osteoarthritis of the knee.
Academic Article Towards a mechanism-based approach to pain management in osteoarthritis.
Academic Article Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (Aggrecanase 1).
Academic Article Osteoarthritis joint pain: the cytokine connection.
Academic Article Nanoparticles for improved local retention after intra-articular injection into the knee joint.
Academic Article A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.
Academic Article Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets.
Academic Article Transport and equilibrium uptake of a peptide inhibitor of PACE4 into articular cartilage is dominated by electrostatic interactions.
Academic Article The usual suspects: verdict not guilty?
Academic Article ADAMTS-4 (aggrecanase-1): N-terminal activation mechanisms.
Academic Article On the predictive utility of animal models of osteoarthritis.
Academic Article ADAMTS-5 deficient mice do not develop mechanical allodynia associated with osteoarthritis following medial meniscal destabilization.
Academic Article PCSK6-mediated corin activation is essential for normal blood pressure.
Academic Article Structural and inhibition analysis reveals the mechanism of selectivity of a series of aggrecanase inhibitors.
Academic Article Standardization of nutrient media for isolated human articular chondrocytes in gelified agarose suspension culture.
Academic Article Blockade of IL-12 during the induction of collagen-induced arthritis (CIA) markedly attenuates the severity of the arthritis.
Academic Article The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action.
Academic Article The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
Academic Article Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies.
Academic Article The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation.
Academic Article P-selectin glycoprotein ligand 1 therapy ameliorates established collagen-induced arthritis in DBA/1 mice partly through the suppression of tumour necrosis factor.
Academic Article Will the real aggrecanase(s) step up: evaluating the criteria that define aggrecanase activity in osteoarthritis.
Academic Article Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation.
Academic Article Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8).
Academic Article An immunoaffinity liquid chromatography-tandem mass spectrometry assay for detection of endogenous aggrecan fragments in biological fluids: Use as a biomarker for aggrecanase activity and cartilage degradation.
Academic Article Chemogenetic Inhibition of Pain Neurons in a Mouse Model of Osteoarthritis.
Academic Article Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification.
Academic Article Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis.
Academic Article Spinal microglial activation in a murine surgical model of knee osteoarthritis.
Academic Article Nerve growth factor blockade for the management of osteoarthritis pain: what can we learn from clinical trials and preclinical models?
Academic Article CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy.
Academic Article Can we target CCR2 to treat osteoarthritis? The trick is in the timing!
Academic Article Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis.
Academic Article Combination therapy with DMARDs and biological agents in collagen-induced arthritis.
Academic Article Anti-IL-12 and anti-TNF antibodies synergistically suppress the progression of murine collagen-induced arthritis.
Academic Article Suppression of TNF-alpha expression, inhibition of Th1 activity, and amelioration of collagen-induced arthritis by rolipram.
Academic Article DBA/1 mice expressing the human TNF-alpha transgene develop a severe, erosive arthritis: characterization of the cytokine cascade and cellular composition.
Academic Article Why we should study pain in animal models of rheumatic diseases.
Academic Article Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging.
Academic Article Peripheral Mechanisms Contributing to Osteoarthritis Pain.
Academic Article An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2.
Academic Article Osteoarthritis pain: What are we learning from animal models?
Academic Article Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety.
Academic Article The nociceptive innervation of the normal and osteoarthritic mouse knee.
Academic Article An emerging role for Toll-like receptors at the neuroimmune interface in osteoarthritis.
Academic Article The innate immune response as a mediator of osteoarthritis pain.
Academic Article Microarray analyses of the dorsal root ganglia support a role for innate neuro-immune pathways in persistent pain in experimental osteoarthritis.
Academic Article Targeting neurotrophic factors: Novel approaches to musculoskeletal pain.
Academic Article Pain-related behaviors and abnormal cutaneous innervation in a murine model of classical Ehlers-Danlos syndrome.
Academic Article The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice.
Academic Article Mitochondrial calcium uniporter deletion prevents painful diabetic neuropathy by restoring mitochondrial morphology and dynamics.
Academic Article Animal Models of Ehlers-Danlos Syndromes: Phenotype, Pathogenesis, and Translational Potential.

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