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One or more keywords matched the following properties of Landay, Alan
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overview Other Appointments: The Thomas J. Coogan, Sr., MD, Chair of Immunology, Rush Medical College. Alan L. Landay, PhD, is the professor of the Department of Immunity & Emerging Pathogens and principal investigator of the Rush Immunology Specialty Laboratory, or ISL, with 35 years experience in studies of HIV immunopathogenesis. He has worked with the AIDS Clinical Trials Group since its beginning and has directed the ISL since it began. His studies on immunophenotyping and innate immunity in HIV disease have made significant contributions to this field. These early studies were carried out in a newly recognized population of hemophiliacs that were shown to develop AIDS. This work was extended with more recent publications using multi-parameter flow cytometry to define monocyte subsets and the critical role of monocytes and innate immune cell activation in HIV pathogenesis. These papers have contributed to a shift in thinking about HIV as an adaptive immune disease to one focused on innate cell driven inflammation linked to the development of immunosenescence. My Scopus ID is 14325119400. My NIH COMMONS name is ALANDAY. Research Areas: HIV/AIDS, aging. My Faculty Profile at Rush University Medical Center: https://www.rushu.rush.edu/faculty/alan-l-landay-phd My Laboratory: https://www.rushu.rush.edu/research/departmental-research/microbial-pathogens-and-immunity-research/laboratory-alan-landay-phd My NCBI Bibliography: https://www.ncbi.nlm.nih.gov/pubmed/?term=Landay+A My Scopus: https://www.scopus.com/authid/detail.uri?authorId=14325119400 Education: PhD, University of Pittsburgh Medical School BS, Penn State University
One or more keywords matched the following items that are connected to Landay, Alan
Item TypeName
Concept Inflammation
Concept Inflammation Mediators
Academic Article Treatment-related changes in serum lipids and inflammation: clinical relevance remains unclear. Analyses from the Women's Interagency HIV study.
Academic Article Inflammatory biomarkers and abacavir use in the Women's Interagency HIV Study and the Multicenter AIDS Cohort Study.
Academic Article Does systemic inflammation and immune activation contribute to fracture risk in HIV?
Academic Article Effector and regulatory roles for B cells in HIV infection?
Academic Article The Association of Human Cytomegalovirus with Biomarkers of Inflammation and Immune Activation in HIV-1-Infected Women.
Academic Article Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication.
Academic Article Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection.
Academic Article Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques.
Academic Article Using the pathogenic and nonpathogenic nonhuman primate model for studying non-AIDS comorbidities.
Academic Article Early immune senescence in HIV disease.
Academic Article T cell activation predicts carotid artery stiffness among HIV-infected women.
Academic Article Interleukin 10 responses are associated with sustained CD4 T-cell counts in treated HIV infection.
Academic Article Liver X receptor alpha (LXRalpha) as a therapeutic target in chronic lymphocytic leukemia (CLL).
Academic Article Biomarkers of immune dysfunction in HIV.
Academic Article Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy - ACTG A5286.
Academic Article Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.
Academic Article The effect of HIV infection and HAART on inflammatory biomarkers in a population-based cohort of women.
Academic Article Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.
Academic Article Glucose transporter 1-expressing proinflammatory monocytes are elevated in combination antiretroviral therapy-treated and untreated HIV+ subjects.
Academic Article Association of Macrophage Inflammation Biomarkers With Progression of Subclinical Carotid Artery Atherosclerosis in HIV-Infected Women and Men.
Academic Article Changes in Inflammation but Not in T-Cell Activation Precede Non-AIDS-Defining Events in a Case-Control Study of Patients on Long-term Antiretroviral Therapy.
Academic Article Gut Microbial-Related Choline Metabolite Trimethylamine-N-Oxide Is Associated With Progression of Carotid Artery Atherosclerosis in HIV Infection.
Academic Article Food Insecurity Is Associated With Inflammation Among Women Living With HIV.
Academic Article Induction of HIF-1a by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation.
Academic Article Soluble Urokinase Plasminogen Activator Receptor Is Predictive of Non-AIDS Events During Antiretroviral Therapy-mediated Viral Suppression.
Academic Article A Randomized, Double-blinded, Placebo-controlled Trial of Sitagliptin for Reducing Inflammation and Immune Activation in Treated and Suppressed Human Immunodeficiency Virus Infection.
Academic Article Elevated Plasma Ceramides Are Associated With Antiretroviral Therapy Use and Progression of Carotid Artery Atherosclerosis in HIV Infection.
Academic Article Stability of plasma indices of inflammation/coagulation and homeostasis after fatty and non-fatty meals in treated people with HIV.
Academic Article Immunological and Neurometabolite Changes Associated With Switch From Efavirenz to an Integrase Inhibitor.
Academic Article The E3 ubiquitin ligase CHIP in normal cell function and in disease conditions.
Academic Article Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment.
Academic Article High-fat diet exacerbates SIV pathogenesis and accelerates disease progression.
Academic Article Upregulation of IL-32 Isoforms in Virologically Suppressed HIV-Infected Individuals: Potential Role in Persistent Inflammation and Transcription From Stable HIV-1 Reservoirs.
Academic Article Dysfunctional Immunometabolism in HIV Infection: Contributing Factors and Implications for Age-Related Comorbid Diseases.
Academic Article Classical monocyte transcriptomes reveal significant anti-inflammatory statin effect in women with chronic HIV.
Academic Article Schistosomiasis is associated with rectal mucosal inflammation among Kenyan men who have sex with men.
Academic Article COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions.
Academic Article Menopause Is Associated With Immune Activation in Women With HIV.
Academic Article Plasma Markers of Disrupted Gut Permeability in Severe COVID-19 Patients.
Academic Article Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV.
Academic Article The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection.
Academic Article HIV and Aging in the Era of ART and COVID-19: Symposium Overview.
Academic Article Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study.
Academic Article Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-?B signaling.
Academic Article Associations between host microbiome and inflammation suggest role for host microbiome in driving COVID-19 disease severity.
Academic Article HIV infection and cardiovascular disease have both shared and distinct monocyte gene expression features: Women's Interagency HIV study.
Academic Article Gut microbiota, circulating inflammatory markers and metabolites, and carotid artery atherosclerosis in HIV infection.
Academic Article Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis.
Academic Article Interleukin 6 Blockade With Tocilizumab Diminishes Indices of Inflammation That Are Linked to Mortality in Treated Human Immunodeficiency Virus Infection.
Academic Article Serotonin reduction in post-acute sequelae of viral infection.
Academic Article HIV and comorbidities - the importance of gut inflammation and the kynurenine pathway.
Academic Article T cell activation is insufficient to drive SIV disease progression.
Academic Article Obesity in HIV infection: host-pathogen interaction.
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  • Inflammation