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One or more keywords matched the following properties of Landay, Alan
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overview Other Appointments: The Thomas J. Coogan, Sr., MD, Chair of Immunology, Rush Medical College. Alan L. Landay, PhD, is the professor of the Department of Immunity & Emerging Pathogens and principal investigator of the Rush Immunology Specialty Laboratory, or ISL, with 35 years experience in studies of HIV immunopathogenesis. He has worked with the AIDS Clinical Trials Group since its beginning and has directed the ISL since it began. His studies on immunophenotyping and innate immunity in HIV disease have made significant contributions to this field. These early studies were carried out in a newly recognized population of hemophiliacs that were shown to develop AIDS. This work was extended with more recent publications using multi-parameter flow cytometry to define monocyte subsets and the critical role of monocytes and innate immune cell activation in HIV pathogenesis. These papers have contributed to a shift in thinking about HIV as an adaptive immune disease to one focused on innate cell driven inflammation linked to the development of immunosenescence. My Scopus ID is 14325119400. My NIH COMMONS name is ALANDAY. Research Areas: HIV/AIDS, aging. My Faculty Profile at Rush University Medical Center: https://www.rushu.rush.edu/faculty/alan-l-landay-phd My Laboratory: https://www.rushu.rush.edu/research/departmental-research/microbial-pathogens-and-immunity-research/laboratory-alan-landay-phd My NCBI Bibliography: https://www.ncbi.nlm.nih.gov/pubmed/?term=Landay+A My Scopus: https://www.scopus.com/authid/detail.uri?authorId=14325119400 Education: PhD, University of Pittsburgh Medical School BS, Penn State University
One or more keywords matched the following items that are connected to Landay, Alan
Item TypeName
Concept Immunity, Cellular
Concept Immunity
Concept Immunity, Mucosal
Concept Adaptive Immunity
Concept Immunity, Innate
Concept Immunity, Humoral
Academic Article HIV-associated mucosal gene expression: region-specific alterations.
Academic Article Relationship between target cell cycle and susceptibility to natural killer lysis.
Academic Article Maternal immunologic and virologic risk factors for infant human immunodeficiency virus type 1 infection: findings from the Women and Infants Transmission Study.
Academic Article Characterization of quantitative and functional innate immune parameters in HIV-1-infected Colombian children receiving stable highly active antiretroviral therapy.
Academic Article The role of bacterial vaginosis and trichomonas in HIV transmission across the female genital tract.
Academic Article The relationship of T-regulatory cell subsets to disease stage, immune activation, and pathogen-specific immunity in HIV infection.
Academic Article Innate immunity and chronic immune activation in HCV/HIV-1 co-infection.
Academic Article An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia.
Academic Article Immunogenetic control of the immune response to gliosarcoma 9L growth in rats.
Academic Article CD16+ NK lymphoproliferative disorders: cellular and molecular characterization.
Academic Article Vaccines and immunology. Recent advances in HIV/AIDS vaccine development.
Academic Article Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanisms.
Academic Article Biology of mucosally transmitted sexual infection-translating the basic science into novel HIV intervention: a workshop summary.
Academic Article Association of chronic hepatitis C infection with T-cell phenotypes in HIV-negative and HIV-positive women.
Academic Article Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals.
Academic Article A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.
Academic Article Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Na?ve to Antiretroviral Therapy: A Pilot Randomized Trial.
Academic Article HIV infection and aging of the innate immune system.
Academic Article Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women.
Academic Article The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1.
Academic Article HIV in the female genital tract: viral shedding and mucosal immunity.
Academic Article Characterization of IL-22 and IL-17 Expressing Leukocytes in the Cervix.
Academic Article Acquired immunodeficiency syndrome with Pneumocystis carinii pneumonia and Mycobacterium avium-intracellulare infection in a previously healthy patient with classic hemophilia. Clinical, immunologic, and virologic findings.
Academic Article Innate immune defenses in HIV-1 infection: prospects for a novel immune therapy.
Academic Article Increased IFN-gamma production by NK and CD3+/CD56+ cells in sexually HIV-1-exposed but uninfected individuals.
Academic Article The effects of commensal bacteria on innate immune responses in the female genital tract.
Academic Article Cervicovaginal levels of lactoferrin, secretory leukocyte protease inhibitor, and RANTES and the effects of coexisting vaginoses in human immunodeficiency virus (HIV)-seronegative women with a high risk of heterosexual acquisition of HIV infection.
Academic Article Antibody-dependent cell-mediated cytotoxicity in cervical lavage fluids of human immunodeficiency virus type 1--infected women.
Academic Article Immunologic abnormalities associated with chronic fatigue syndrome.
Academic Article Recombinant human interleukin-1 receptor type I in the treatment of patients with active rheumatoid arthritis.
Academic Article HIV immunology better understood and vaccination attempts started.
Academic Article Early and delayed benefits of HIV-1 suppression: timeline of recovery of innate immunity effector cells.
Academic Article Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.
Academic Article Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Na?ve to Antiretroviral Therapy: A Pilot Randomized Trial.
Academic Article HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood.
Academic Article Dendritic cell activation and maturation induced by mucosal fluid from women with bacterial vaginosis.
Academic Article Inside Out: HIV, the Gut Microbiome, and the Mucosal Immune System.
Academic Article Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction.
Academic Article Brief Report: Inflammatory Colonic Innate Lymphoid Cells Are Increased During Untreated HIV-1 Infection and Associated With Markers of Gut Dysbiosis and Mucosal Immune Activation.
Academic Article The TLR9 agonist MGN1703 triggers a potent type I interferon response in the sigmoid colon.
Academic Article Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Na?ve to Antiretroviral Therapy: A Pilot Randomized Trial.
Academic Article The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis.
Academic Article The E3 ubiquitin ligase CHIP in normal cell function and in disease conditions.
Academic Article Associations of Innate and Adaptive Immune Cell Subsets With Incident Type 2 Diabetes Risk: The MESA Study.
Academic Article Innate and adaptive immune cell subsets as risk factors for coronary heart disease in two population-based cohorts.
Academic Article Natural killer cells, gamma delta T cells and classical monocytes are associated with systolic blood pressure in the multi-ethnic study of atherosclerosis (MESA).
Academic Article COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions.
Academic Article The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection.
Academic Article Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time.
Academic Article Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis.
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  • Immunity