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Landay, Alan
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overview Other Appointments: The Thomas J. Coogan, Sr., MD, Chair of Immunology, Rush Medical College. Alan L. Landay, PhD, is the professor of the Department of Immunity & Emerging Pathogens and principal investigator of the Rush Immunology Specialty Laboratory, or ISL, with 35 years experience in studies of HIV immunopathogenesis. He has worked with the AIDS Clinical Trials Group since its beginning and has directed the ISL since it began. His studies on immunophenotyping and innate immunity in HIV disease have made significant contributions to this field. These early studies were carried out in a newly recognized population of hemophiliacs that were shown to develop AIDS. This work was extended with more recent publications using multi-parameter flow cytometry to define monocyte subsets and the critical role of monocytes and innate immune cell activation in HIV pathogenesis. These papers have contributed to a shift in thinking about HIV as an adaptive immune disease to one focused on innate cell driven inflammation linked to the development of immunosenescence. My Scopus ID is 14325119400. My NIH COMMONS name is ALANDAY. Research Areas: HIV/AIDS, aging. My Faculty Profile at Rush University Medical Center: https://www.rushu.rush.edu/faculty/alan-l-landay-phd My Laboratory: https://www.rushu.rush.edu/research/departmental-research/microbial-pathogens-and-immunity-research/laboratory-alan-landay-phd My NCBI Bibliography: https://www.ncbi.nlm.nih.gov/pubmed/?term=Landay+A My Scopus: https://www.scopus.com/authid/detail.uri?authorId=14325119400 Education: PhD, University of Pittsburgh Medical School BS, Penn State University
One or more keywords matched the following items that are connected to Landay, Alan
Item TypeName
Concept Precursor Cells, B-Lymphoid
Concept Langerhans Cells
Concept Lymphoma, Large B-Cell, Diffuse
Concept Epithelial Cells
Concept Cell Lineage
Concept Hematopoietic Stem Cells
Concept Jurkat Cells
Concept Receptors, Antigen, T-Cell
Concept T-Cell Antigen Receptor Specificity
Concept HeLa Cells
Concept Cell Division
Concept Leukemia, B-Cell
Concept Dendritic Cells
Concept Blood Cell Count
Concept Programmed Cell Death 1 Receptor
Concept Cell Cycle
Concept Cell Membrane
Concept Cell Culture Techniques
Concept Clone Cells
Concept Myeloid Progenitor Cells
Concept Th1 Cells
Concept Cell Transformation, Neoplastic
Concept Receptors, Cell Surface
Concept Cell Survival
Concept Cell Communication
Concept Cell Adhesion Molecules
Concept Endothelial Cells
Concept Blood Cells
Concept Killer Cells, Lymphokine-Activated
Concept Antigen-Presenting Cells
Concept Stromal Cells
Concept Th2 Cells
Concept Cell Membrane Permeability
Concept Cell Line
Concept Tumor Cells, Cultured
Concept Hematopoietic Stem Cell Mobilization
Concept Cell Differentiation
Concept Cell-Free System
Concept Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Concept Cells
Concept Receptors, Antigen, B-Cell
Concept Leukemia, Lymphocytic, Chronic, B-Cell
Concept Myeloid Cells
Concept Neural Cell Adhesion Molecules
Concept Killer Cells, Natural
Concept Cell Line, Tumor
Concept Th17 Cells
Concept Antibody-Dependent Cell Cytotoxicity
Concept Cells, Cultured
Concept Cell Separation
Concept Natural Killer T-Cells
Concept Cell Proliferation
Concept Cell Count
Concept Single-Cell Analysis
Academic Article T cell responses to recall antigens, alloantigen, and mitogen of HIV-infected patients receiving long-term combined antiretroviral therapy.
Academic Article Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway.
Academic Article Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells.
Academic Article Immunologic studies in asymptomatic hemophilia patients. Relationship to acquired immune deficiency syndrome (AIDS).
Academic Article Relationship between target cell cycle and susceptibility to natural killer lysis.
Academic Article Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin.
Academic Article Characterization of quantitative and functional innate immune parameters in HIV-1-infected Colombian children receiving stable highly active antiretroviral therapy.
Academic Article HIV-1 target cells in foreskins of African men with varying histories of sexually transmitted infections.
Academic Article Viremic and Virologically Suppressed HIV Infection Increases Age-Related Changes to Monocyte Activation Equivalent to 12 and 4 Years of Aging, Respectively.
Academic Article IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.
Academic Article Transmembrane P-glycoprotein (P-gp/P-170) in HIV infection: analysis of lymphocyte surface expression and drug-unrelated function.
Academic Article Monitoring HIV-1 treatment in immune-cell subsets with ultrasensitive fluorescence-in-situ hybridisation.
Academic Article Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response.
Academic Article Chemokine analogues show suitable stability for development as microbicides.
Academic Article Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells.
Academic Article Enumeration of human lymphocyte subpopulations by immunofluorescence: a comparative study using automated flow microfluorometry and fluorescence microscopy.
Academic Article Serum immune activation markers are persistently increased in patients with HIV infection after 6 years of antiretroviral therapy despite suppression of viral replication and reconstitution of CD4+ T cells.
Academic Article In vitro immunologic and virologic effects of interleukin 15 on peripheral blood mononuclear cells from normal donors and human immunodeficiency virus type 1-infected patients.
Academic Article Normal immune function of monocyte-derived dendritic cells from HIV-infected individuals: implications for immunotherapy.
Academic Article Proliferation responses to HIVp24 during antiretroviral therapy do not reflect improved immune phenotype or function.
Academic Article The relationship of T-regulatory cell subsets to disease stage, immune activation, and pathogen-specific immunity in HIV infection.
Academic Article Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation.
Academic Article Anti-cellular antibodies in sera from vaccinated macaques can induce complement-mediated virolysis of human immunodeficiency virus and simian immunodeficiency virus.
Academic Article Microbiome alterations in HIV infection a review.
Academic Article Invariant NKT cells from HIV-1 or Mycobacterium tuberculosis-infected patients express an activated phenotype.
Academic Article Shipment impairs lymphocyte proliferative responses to microbial antigens.
Academic Article GB virus C particles inhibit T cell activation via envelope E2 protein-mediated inhibition of TCR signaling.
Academic Article HIV infection of primary CD4+ Th2 cells, defined by expression of the chemoattractant receptor-homologous (CRTH2), induces a Th0 phenotype.
Academic Article Dysregulated B-cell TLR2 expression and elevated regulatory B-cell frequency precede the diagnosis of AIDS-related non-Hodgkin lymphoma.
Academic Article Correlation of serum HIV antigen and antibody with clinical status in HIV-infected patients.
Academic Article Whole blood method for simultaneous detection of surface and cytoplasmic antigens by flow cytometry.
Academic Article Innate immunity and chronic immune activation in HCV/HIV-1 co-infection.
Academic Article A role for TLR signaling during B cell activation in antiretroviral-treated HIV individuals.
Academic Article Systemic Cytokine Levels Do Not Predict CD4(+) T-Cell Recovery After Suppressive Combination Antiretroviral Therapy in Chronic Human Immunodeficiency Virus Infection.
Academic Article Idiotypic analysis of a B cell clone with anti-intermediate filament specificity in a patient with Sj?gren's syndrome: involvement of five subpopulations producing different immunoglobulin isotypes.
Academic Article Immunogenetic control of the immune response to gliosarcoma 9L growth in rats.
Academic Article HIV infection perturbs DNA content of lymphoid cells: partial correction after 'suppression' of virus replication.
Academic Article Costimulation of naive CD8(+) lymphocytes induces CD4 expression and allows human immunodeficiency virus type 1 infection.
Academic Article Effector and regulatory roles for B cells in HIV infection?
Academic Article In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10.
Academic Article Changes in human immunodeficiency virus type 1 virus load during mobilization and harvesting of hemopoietic progenitor cells. Adult AIDS Clinical Trials Group 285 Study Team.
Academic Article Neutralization of human immunodeficiency virus type 1 by complement occurs by viral lysis.
Academic Article Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection.
Academic Article Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells.
Academic Article T-cell receptor gene rearrangement and expression in human natural killer cells: natural killer activity is not dependent on the rearrangement and expression of T-cell receptor alpha, beta, or gamma genes.
Academic Article A human immunodeficiency virus (HIV)-inducing factor from the female genital tract activates HIV-1 gene expression through the kappaB enhancer.
Academic Article The Association of Human Cytomegalovirus with Biomarkers of Inflammation and Immune Activation in HIV-1-Infected Women.
Academic Article Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response?
Academic Article Induction of HIV-1 replication by type 1-like cytokines, interleukin (IL)-12 and IL-15: effect on viral transcriptional activation, cellular proliferation, and endogenous cytokine production.
Academic Article Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads.
Academic Article CD16+ NK lymphoproliferative disorders: cellular and molecular characterization.
Academic Article Characterization of a phenotypically distinct subpopulation of Leu-2+ cells that suppresses T cell proliferative responses.
Academic Article Short-chain fatty acids induce pro-inflammatory cytokine production alone and in combination with toll-like receptor ligands.
Academic Article Evaluating the impact of hepatitis C virus (HCV) on highly active antiretroviral therapy-mediated immune responses in HCV/HIV-coinfected women: role of HCV on expression of primed/memory T cells.
Academic Article Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA.
Academic Article The relation of plasmacytoid dendritic cells (pDCs) and regulatory T-cells (Tregs) with HPV persistence in HIV-infected and HIV-uninfected women.
Academic Article GB virus C infection and B-cell, natural killer cell, and monocyte activation markers in HIV-infected individuals.
Academic Article HIV infection: diagnosis and disease progression evaluation.
Academic Article Phenotypically and functionally distinct subpopulations of human lymphocytes with T cell markers also exhibit different cytochemical patterns of staining for lysosomal enzymes.
Academic Article Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11.
Academic Article Modulation of TIM-3 expression on NK and T cell subsets in HIV immunological non-responders.
Academic Article IL-10 cooperates with TNF-alpha to activate HIV-1 from latently and acutely infected cells of monocyte/macrophage lineage.
Academic Article CD28-negative CD4+ and CD8+ T cells in antiretroviral therapy-naive HIV-infected adults enrolled in adult clinical trials group studies.
Academic Article Reconstitution of long-term T helper cell function after zidovudine therapy in human immunodeficiency virus-infected patients.
Academic Article Activation of complement on the surface of cells infected by human immunodeficiency virus.
Academic Article A lymphoproliferative disorder of granular lymphocytes with a novel phenotype and suppressor function.
Academic Article Preservation of lymphocyte immunophenotype and proliferative responses in cryopreserved peripheral blood mononuclear cells from human immunodeficiency virus type 1-infected donors: implications for multicenter clinical trials. The ACTG Immunology Advanced Technology Laboratories.
Academic Article Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection.
Academic Article PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes.
Academic Article Antibodies to human T-cell leukemia virus membrane antigens (HTLV-MA) in hemophiliacs.
Academic Article TLR2-activated B cells are phenotypically similar to the abnormal circulating B cells seen preceding the diagnosis of AIDS-related NHL diagnosis.
Academic Article Intracellular Casp8p41 content is inversely associated with CD4 T cell count.
Academic Article Multiple patterns of alloantigen presenting/stimulating cell dysfunction in patients with AIDS.
Academic Article Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women.
Academic Article A North American multilaboratory study of CD4 counts using flow cytometric panLeukogating (PLG): a NIAID-DAIDS Immunology Quality Assessment Program Study.
Academic Article Baseline levels of soluble CD14 and CD16+56- natural killer cells are negatively associated with response to interferon/ribavirin therapy during HCV-HIV-1 coinfection.
Academic Article The immunologic effects of maraviroc intensification in treated HIV-infected individuals with incomplete CD4+ T-cell recovery: a randomized trial.
Academic Article Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells.
Academic Article Regulation of CCR5 and CXCR4 expression by type 1 and type 2 cytokines: CCR5 expression is downregulated by IL-10 in CD4-positive lymphocytes.
Academic Article Effect of mucosal fluid from women with bacterial vaginosis on HIV trans-infection mediated by dendritic cells.
Academic Article A rapid manual method for CD4+ T-cell quantitation for use in developing countries.
Academic Article A potent activator of HIV-1 replication is present in the genital tract of a subset of HIV-1-infected and uninfected women.
Academic Article Flow cytometry evaluation of cell-mediated cytotoxicity.
Academic Article Effect of zidovudine therapy on CD8+ T cell anti-HIV activity.
Academic Article Function and phenotype of immature CD4+ lymphocytes in healthy infants and early lymphocyte activation in uninfected infants of human immunodeficiency virus-infected mothers.
Academic Article Trophoblasts are productively infected by CD4-independent isolate of HIV type 1.
Academic Article Distinct mechanisms of T cell reconstitution can be identified by estimating thymic volume in adult HIV-1 disease.
Academic Article Complement and antibody mediate enhancement of HIV infection by increasing virus binding and provirus formation.
Academic Article A human B cell differentiation antigen selectively expressed on mature B cells identified by a monoclonal antibody (HB-2).
Academic Article Discordant expression of CD3 and T-cell receptor antigens on lymphocytes from patients treated with OKT3.
Academic Article Lineage and stage specificity of isotype switching in humans.
Academic Article Proinflammatory and type 1 cytokine expression in cervical mucosa during HIV-1 and human papillomavirus infection.
Academic Article Association of chronic hepatitis C infection with T-cell phenotypes in HIV-negative and HIV-positive women.
Academic Article VACUTAINER CPT and Ficoll density gradient separation perform equivalently in maintaining the quality and function of PBMC from HIV seropositive blood samples.
Academic Article Comparison of immunologic assays for detecting immune responses in HIV immunotherapeutic studies: AIDS Clinical Trials Group Trial A5181.
Academic Article Human immunodeficiency virus (HIV)-infected cells and free virus directly activate the classical complement pathway in rabbit, mouse and guinea-pig sera; activation results in virus neutralization by virolysis.
Academic Article Characterization of human lymphocyte subpopulations: alloreactive cytotoxic T-lymphocyte precursor and effector cells are phenotypically distinct from Leu 2+ suppressor cells.
Academic Article Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands.
Academic Article GB virus C infection is associated with altered lymphocyte subset distribution and reduced T cell activation and proliferation in HIV-infected individuals.
Academic Article In vivo decrease in the expression of complement receptor 2 on B-cells in HIV infection.
Academic Article T cell activation predicts carotid artery stiffness among HIV-infected women.
Academic Article Delaying a treatment switch in antiretroviral-treated HIV type 1-infected patients with detectable drug-resistant viremia does not have a profound effect on immune parameters: AIDS Clinical Trials Group Study A5115.
Academic Article Characterization of CD4? T-cell immune activation and interleukin 10 levels among HIV, hepatitis C virus, and HIV/HCV-coinfected patients.
Academic Article Interleukin 10 responses are associated with sustained CD4 T-cell counts in treated HIV infection.
Academic Article Saliva can mediate HIV-1-specific antibody-dependent cell-mediated cytotoxicity.
Academic Article The effect of aging on T-regulatory cell frequency in HIV infection.
Academic Article Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes.
Academic Article Flow cytometric monitoring of human immunodeficiency virus-infected patients. Simultaneous enumeration of five lymphocyte subsets.
Academic Article Differential surface marker expression in patients with CD-16+ lymphoproliferative disorders: in vivo model for NK differentiation.
Academic Article Liver X receptor alpha (LXRalpha) as a therapeutic target in chronic lymphocytic leukemia (CLL).
Academic Article Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8? T cell function in vitro.
Academic Article Identification and functional characterization of mononuclear cells by flow cytometry.
Academic Article Advances in CD4 cell enumeration in resource-poor countries.
Academic Article Older age is associated with peripheral blood expansion of na?ve B cells in HIV-infected subjects on antiretroviral therapy.
Academic Article Elevated caspase-3 expression and T-cell activation in elite suppressors.
Academic Article Quantitative single cell methods that identify cytokine and chemokine expression in dendritic cells.
Academic Article Gamma/delta T cell receptor positive T cells in the inflammatory joint: lack of association with response to soluble antigens.
Academic Article HTLV-I activates complement leading to increased binding to complement receptor-positive cells.
Academic Article Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals.
Academic Article A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers.
Academic Article Postmortem recovery of human immunodeficiency virus type 1 from plasma and mononuclear cells. Implications for occupational exposure.
Academic Article Preferential expression of neo-CRP epitopes on the surface of human peripheral blood lymphocytes.
Academic Article Repertoire of chemokine receptor expression in the female genital tract: implications for human immunodeficiency virus transmission.
Academic Article Isolation of HIV-1 from monocytes of individuals negative by conventional culture.
Academic Article Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus.
Academic Article Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection.
Academic Article Small differences in CD4+ T-cell production may go unnoticed.
Academic Article Direct binding of complement component C1q to human immunodeficiency virus (HIV) and human T lymphotrophic virus-I (HTLV-I) coinfected cells.
Academic Article In vitro cell-mediated immune responses of human immunodeficiency virus-infected and -uninfected individuals to whole cytomegalovirus antigens and their subunits.
Academic Article Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women.
Academic Article Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy - ACTG A5286.
Academic Article A Phase I, placebo-controlled trial of multi-dose recombinant human interleukin-12 in patients with HIV infection.
Academic Article CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus.
Academic Article Detection of HIV-1 provirus in bronchoalveolar lavage cells by polymerase chain reaction.
Academic Article Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women.
Academic Article Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction.
Academic Article Complement activation by human monoclonal antibodies to human immunodeficiency virus.
Academic Article Phenotypic analysis of complement receptor 2+ T lymphocytes: reduced expression on CD4+ cells in HIV-infected persons.
Academic Article CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV.
Academic Article Reduced mobilization of CD34+ stem cells in advanced human immunodeficiency virus type 1 disease.
Academic Article Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue.
Academic Article Increases in T cell telomere length in HIV infection after antiretroviral combination therapy for HIV-1 infection implicate distinct population dynamics in CD4+ and CD8+ T cells.
Academic Article T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women.
Academic Article Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.
Academic Article Characterization of IL-22 and IL-17 Expressing Leukocytes in the Cervix.
Academic Article Immune responses to abacavir in antigen-presenting cells from hypersensitive patients.
Academic Article A pilot trial of adding maraviroc to suppressive antiretroviral therapy for suboptimal CD4? T-cell recovery despite sustained virologic suppression: ACTG A5256.
Academic Article Increased IFN-gamma production by NK and CD3+/CD56+ cells in sexually HIV-1-exposed but uninfected individuals.
Academic Article Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection.
Academic Article Dysfunctional natural killer cells, in vivo, are governed by HIV viremia regardless of whether the infected individual is on antiretroviral therapy.
Academic Article Bacterial vaginosis-associated microflora isolated from the female genital tract activates HIV-1 expression.
Academic Article Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy.
Academic Article Differential CD4+ cell count increase and CD4+?: ?CD8+ ratio normalization with maraviroc compared with tenofovir.
Academic Article Monocyte functional studies in asymptomatic, human immunodeficiency disease virus (HIV)-infected individuals.
Academic Article Antibody-dependent cell-mediated cytotoxicity in cervical lavage fluids of human immunodeficiency virus type 1--infected women.
Academic Article Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection.
Academic Article Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates.
Academic Article Immunologic abnormalities associated with chronic fatigue syndrome.
Academic Article Immunogenetic and immunologic aspects of gliosarcoma growth in rats.
Academic Article Interferon-alpha administration enhances CD8+ T cell activation in HIV infection.
Academic Article In vitro evaluation of intestinal epithelial TLR activation in preventing food allergic responses.
Academic Article CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection.
Academic Article C-reactive protein antigenicity on the surface of human peripheral blood lymphocytes. Characterization of lymphocytes reactive with anti-neo-CRP.
Academic Article Evidence of a selective depletion of a CD16+ CD56+ CD8+ natural killer cell subset during HIV infection.
Academic Article Isotype switching in human B lymphocyte malignancies occurs by DNA deletion: evidence for nonspecific switch recombination.
Academic Article A potential role for interleukin-7 in T-cell homeostasis.
Academic Article Depletion of latent HIV-1 infection in vivo: a proof-of-concept study.
Academic Article Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells.
Academic Article Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment.
Academic Article Identification of a population of large granular lymphocytes obtained from the rheumatoid joint coexpressing the CD3 and CD16 antigens.
Academic Article Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women.
Academic Article Flow cytometry of urine.
Academic Article Evaluation of the impact of highly active antiretroviral therapy on immune recovery in antiretroviral naive patients.
Academic Article Regulatory B cells inhibit cytotoxic T lymphocyte (CTL) activity and elimination of infected CD4 T cells after in vitro reactivation of HIV latent reservoirs.
Academic Article Soluble CD163 is associated with noninvasive measures of liver fibrosis in hepatitis C virus- and hepatitis C virus/human immunodeficiency virus-infected women.
Academic Article Cellular restoration in HIV infected persons treated with abacavir and a protease inhibitor: age inversely predicts naive CD4 cell count increase.
Academic Article Antigen-presenting cells in HIV pathogenesis and therapy: summary of the October 17-18, 2002, Think Tank meeting.
Academic Article Human herpesvirus 6 inhibits human immunodeficiency virus type 1 replication in cell culture.
Academic Article Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells.
Academic Article An activated CD8+ T cell phenotype correlates with anti-HIV activity and asymptomatic clinical status.
Academic Article Characterization of circulating suppressor T lymphocytes in bone marrow transplant recipients.
Academic Article Early and delayed benefits of HIV-1 suppression: timeline of recovery of innate immunity effector cells.
Academic Article Optimizing viable leukocyte sampling from the female genital tract for clinical trials: an international multi-site study.
Academic Article Evaluation of thymopoiesis using T cell receptor excision circles (TRECs): differential correlation between adult and pediatric TRECs and na?ve phenotypes.
Academic Article Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA).
Academic Article MDSC: a new player in HIV immunopathogenesis.
Academic Article Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.
Academic Article Cell-associated genital tract virus and vertical transmission of human immunodeficiency virus type 1 in antiretroviral-experienced women.
Academic Article Dendritic cell activation and maturation induced by mucosal fluid from women with bacterial vaginosis.
Academic Article A look at HIV immune research. Interview by Alan Huff.
Academic Article CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.
Academic Article The Role of Antigen-presenting Cells in HIV Pathogenesis.
Academic Article Higher Body Mass Index Is Associated With Greater Proportions of Effector CD8+ T Cells Expressing CD57 in Women Living With HIV.
Academic Article Brief Report: CD14brightCD16- monocytes and sCD14 level negatively associate with CD4-memory T-cell frequency and predict HCV-decline on therapy.
Academic Article Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction.
Academic Article Brief Report: Inflammatory Colonic Innate Lymphoid Cells Are Increased During Untreated HIV-1 Infection and Associated With Markers of Gut Dysbiosis and Mucosal Immune Activation.
Academic Article CD56bright NK IL-7Ra expression negatively associates with HCV level, and IL-7-induced NK function is impaired during HCV and HIV infections.
Academic Article The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis.
Academic Article FcRL4 Expression Identifies a Pro-inflammatory B Cell Subset in Viremic HIV-Infected Subjects.
Academic Article Changes in Inflammation but Not in T-Cell Activation Precede Non-AIDS-Defining Events in a Case-Control Study of Patients on Long-term Antiretroviral Therapy.
Academic Article Diminished antibody response to influenza vaccination is characterized by expansion of an age-associated B-cell population with low PAX5.
Academic Article Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule-Restricted Peptide Epitopes of Apolipoprotein B.
Academic Article Biomarkers Associated with Death After Initiating Treatment for Tuberculosis and HIV in Patients with Very Low CD4 Cells.
Academic Article Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals.
Academic Article Induction of HIF-1a by HIV-1 Infection in CD4+ T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation.
Academic Article Antiretroviral Therapy Reduces T-cell Activation and Immune Exhaustion Markers in Human Immunodeficiency Virus Controllers.
Academic Article The E3 ubiquitin ligase CHIP in normal cell function and in disease conditions.
Academic Article Associations of Innate and Adaptive Immune Cell Subsets With Incident Type 2 Diabetes Risk: The MESA Study.
Academic Article Innate and adaptive immune cell subsets as risk factors for coronary heart disease in two population-based cohorts.
Academic Article Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy.
Academic Article Association of Monocyte Migration Marker CD11b With Pulmonary Function in People Living With HIV.
Academic Article Food Insecurity and T-cell Dysregulation in Women Living With Human Immunodeficiency Virus on Antiretroviral Therapy.
Academic Article Natural killer cells, gamma delta T cells and classical monocytes are associated with systolic blood pressure in the multi-ethnic study of atherosclerosis (MESA).
Academic Article COVID-19 Severity Is Associated with Differential Antibody Fc-Mediated Innate Immune Functions.
Academic Article Overt IL-32 isoform expression at intestinal level during HIV-1 infection is negatively regulated by IL-17A.
Academic Article Loss of CD96 Expression as a Marker of HIV-Specific CD8+ T-Cell Differentiation and Dysfunction.
Academic Article The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection.
Academic Article T-Cell Immune Dysregulation and Mortality in Women With Human Immunodeficiency Virus.
Academic Article IL-17A reprograms intestinal epithelial cells to facilitate HIV-1 replication and outgrowth in CD4+ T?cells.
Academic Article Circulating CD4+ TEMRA and CD4+ CD28- T cells and incident diabetes among persons with and without HIV.
Academic Article Editorial: Advances in T Cell Therapeutic Vaccines for HIV.
Academic Article Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study.
Academic Article Elevated CD4 + T-cell glucose metabolism in HIV+ women with diabetes mellitus.
Academic Article Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells.
Academic Article T-cell activation state differentially contributes to neuropsychiatric complications in women with HIV.
Academic Article Differential Impact of IL-32 Isoforms on the Functions of Coronary Artery Endothelial Cells: A Potential Link with Arterial Stiffness and Atherosclerosis.
Academic Article Can statin preventative treatment inform geroscience-guided therapeutics?
Academic Article Serotonin reduction in post-acute sequelae of viral infection.
Academic Article Author Correction: Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells.
Academic Article Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2.
Academic Article Association of Immune Cell Subsets with Incident Hip Fracture: The Cardiovascular Health Study.
Academic Article T cell activation is insufficient to drive SIV disease progression.
Academic Article Single cell transcriptomics and TCR reconstruction reveal CD4 T cell response to MHC-II-restricted APOB epitope in human cardiovascular disease.
Academic Article IL-32 Drives the Differentiation of Cardiotropic CD4+ T-Cells Carrying HIV DNA in People Living with HIV.
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