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Kordower, Jeffrey

One or more keywords matched the following items that are connected to Kordower, Jeffrey

Item Type	Name
Concept	Receptor Protein-Tyrosine Kinases
Concept	Tyrosine 3-Monooxygenase
Concept	Tyrosine
Academic Article	Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains.
Academic Article	Neuropathological study 16 years after autologous adrenal medullary transplantation in a Parkinson's disease patient.
Academic Article	Decreased alpha-synuclein expression in the aging mouse substantia nigra.
Academic Article	Nurr1 in Parkinson's disease and related disorders.
Academic Article	Transgene expression, bioactivity, and safety of CERE-120 (AAV2-neurturin) following delivery to the monkey striatum.
Academic Article	Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
Academic Article	Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism.
Academic Article	Expression, bioactivity, and safety 1 year after adeno-associated viral vector type 2-mediated delivery of neurturin to the monkey nigrostriatal system support cere-120 for Parkinson's disease.
Academic Article	Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability.
Academic Article	Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys.
Academic Article	Transplanted dopaminergic neurons develop PD pathologic changes: a second case report.
Academic Article	Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy.
Academic Article	Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.
Academic Article	Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism.
Academic Article	Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease.
Academic Article	Proteasome inhibition and Parkinson's disease modeling.
Academic Article	Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.
Academic Article	Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease.
Academic Article	Disease duration and the integrity of the nigrostriatal system in Parkinson's disease.
Academic Article	Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease.
Academic Article	Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) alters exploratory behavior, reduces monoamine metabolism, and increases forebrain tyrosine hydroxylase fiber density of juvenile rats.
Academic Article	Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease.
Academic Article	Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra.
Academic Article	Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.
Academic Article	Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease.
Academic Article	Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey.
Academic Article	Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias.
Academic Article	Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient.
Academic Article	Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with a-synucleinopathies.
Academic Article	Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.
Academic Article	Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease.
Academic Article	Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs.
Academic Article	Post-Mortem Studies of Neurturin Gene Therapy for Parkinson's Disease: Two Subjects with 10?Years CERE120 Delivery.

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