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Kordower, Jeffrey
One or more keywords matched the following items that are connected to
Kordower, Jeffrey
Item Type
Name
Concept
Neurons
Concept
Adrenergic Neurons
Concept
GABAergic Neurons
Concept
Dopaminergic Neurons
Academic Article
Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups.
Academic Article
Abnormal alpha-synuclein reduces nigral voltage-dependent anion channel 1 in sporadic and experimental Parkinson's disease.
Academic Article
Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
Academic Article
Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury.
Academic Article
Future of cell and gene therapies for Parkinson's disease.
Academic Article
Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease.
Academic Article
a-synuclein aggregation reduces nigral myocyte enhancer factor-2D in idiopathic and experimental Parkinson's disease.
Academic Article
Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease.
Academic Article
Decreased alpha-synuclein expression in the aging mouse substantia nigra.
Academic Article
Nurr1 in Parkinson's disease and related disorders.
Academic Article
Propagation of host disease to grafted neurons: accumulating evidence.
Academic Article
Human neural stem cell transplants improve motor function in a rat model of Huntington's disease.
Academic Article
Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates.
Academic Article
Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
Academic Article
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.
Academic Article
Age-related accumulation of Marinesco bodies and lipofuscin in rhesus monkey midbrain dopamine neurons: relevance to selective neuronal vulnerability.
Academic Article
Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.
Academic Article
Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys.
Academic Article
Transplanted dopaminergic neurons develop PD pathologic changes: a second case report.
Academic Article
Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.
Academic Article
GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults.
Academic Article
A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease.
Academic Article
Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.
Academic Article
Long-term gonadal hormone treatment and endogenous neurogenesis in the dentate gyrus of the adult female monkey.
Academic Article
Neuropathology in transplants in Parkinson's disease: implications for disease pathogenesis and the future of cell therapy.
Academic Article
Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration.
Academic Article
Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease.
Academic Article
Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease.
Academic Article
Proteasome inhibition and Parkinson's disease modeling.
Academic Article
RET expression does not change with age in the substantia nigra pars compacta of rhesus monkeys.
Academic Article
Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease.
Academic Article
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.
Academic Article
Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
Academic Article
Cell transplantation and gene therapy in Parkinson's disease.
Academic Article
Intrastriatal CERE-120 (AAV-Neurturin) protects striatal and cortical neurons and delays motor deficits in a transgenic mouse model of Huntington's disease.
Academic Article
Delivery of neurturin by AAV2 (CERE-120)-mediated gene transfer provides structural and functional neuroprotection and neurorestoration in MPTP-treated monkeys.
Academic Article
Viral delivery of glial cell line-derived neurotrophic factor improves behavior and protects striatal neurons in a mouse model of Huntington's disease.
Academic Article
Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke.
Academic Article
Disease duration and the integrity of the nigrostriatal system in Parkinson's disease.
Academic Article
Transfer of host-derived a synuclein to grafted dopaminergic neurons in rat.
Academic Article
Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra.
Academic Article
Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys.
Academic Article
The prion hypothesis of Parkinson's disease: this hot topic just got hotter.
Academic Article
Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.
Academic Article
RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus.
Academic Article
Injectable hydrogels providing sustained delivery of vascular endothelial growth factor are neuroprotective in a rat model of Huntington's disease.
Academic Article
Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease.
Academic Article
Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor a.
Academic Article
Fetal grafts for Parkinson's disease: Decades in the making.
Academic Article
Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias.
Academic Article
Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient.
Academic Article
Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates.
Academic Article
Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In?Vivo.
Academic Article
Aging and Parkinson's disease: Different sides of the same coin?
Academic Article
Targeting a-Synuclein as a therapy for Parkinson's disease: The battle begins.
Academic Article
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Academic Article
Is Axonal Degeneration a Key Early Event in Parkinson's Disease?
Academic Article
Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with a-synucleinopathies.
Academic Article
Prenatal exposure to MDMA alters noradrenergic neurodevelopment in the rat.
Academic Article
Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration.
Academic Article
Therapeutic approaches to target alpha-synuclein pathology.
Academic Article
Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA.
Academic Article
Disease Modification Through Trophic Factor Delivery.
Academic Article
Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms.
Academic Article
Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity.
Academic Article
Temporal evolution of microglia and a-synuclein accumulation following foetal grafting in Parkinson's disease.
Academic Article
Spreading of alpha-synuclein - relevant or epiphenomenon?
Academic Article
Intrastriatal alpha-synuclein fibrils in monkeys: spreading, imaging and neuropathological changes.
Academic Article
Does Developmental Variability in the Number of Midbrain Dopamine Neurons Affect Individual Risk for Sporadic Parkinson's Disease?
Academic Article
T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease.
Academic Article
Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease.
Academic Article
GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop.
Academic Article
Anti-a-synuclein ASO delivered to monoamine neurons prevents a-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys.
Academic Article
Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in?vivo.
Academic Article
Viral-based rodent and nonhuman primate models of multiple system atrophy: Fidelity to the human disease.
Academic Article
Corrigendum to "Anti-a-synuclein ASO delivered to monoamine neurons prevents a-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys" [EBioMedicine 2020; 59:102944].
Academic Article
In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain.
Academic Article
Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs.
Academic Article
Post-Mortem Studies of Neurturin Gene Therapy for Parkinson's Disease: Two Subjects with 10?Years CERE120 Delivery.
Search Criteria
Neurons