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Bennett, David

One or more keywords matched the following items that are connected to Bennett, David

Item Type	Name
Concept	Adaptor Proteins, Signal Transducing
Concept	CLOCK Proteins
Concept	Proto-Oncogene Proteins c-myc
Concept	Proto-Oncogene Proteins c-fyn
Concept	Polycomb-Group Proteins
Concept	Vesicular Transport Proteins
Concept	Membrane Proteins
Concept	LDL-Receptor Related Proteins
Concept	A Kinase Anchor Proteins
Concept	Monomeric Clathrin Assembly Proteins
Concept	DNA-Binding Proteins
Concept	Vesicular Acetylcholine Transport Proteins
Concept	14-3-3 Proteins
Concept	Membrane Transport Proteins
Concept	Homeodomain Proteins
Concept	Cytoskeletal Proteins
Concept	Amyloidogenic Proteins
Concept	Muscle Proteins
Concept	Insulin Receptor Substrate Proteins
Concept	Qa-SNARE Proteins
Concept	Fatty Acid-Binding Proteins
Concept	Carrier Proteins
Concept	Cell Cycle Proteins
Concept	Mitochondrial Proteins
Concept	Vesicular Inhibitory Amino Acid Transport Proteins
Concept	GTP-Binding Proteins
Concept	Green Fluorescent Proteins
Concept	Period Circadian Proteins
Concept	SNARE Proteins
Concept	Saccharomyces cerevisiae Proteins
Concept	PrPC Proteins
Concept	HSP27 Heat-Shock Proteins
Concept	HSP70 Heat-Shock Proteins
Concept	Nuclear Proteins
Concept	Recombinant Proteins
Concept	Neoplasm Proteins
Concept	Caenorhabditis elegans Proteins
Concept	Drosophila Proteins
Concept	Microfilament Proteins
Concept	Proto-Oncogene Proteins p21(ras)
Concept	Acute-Phase Proteins
Concept	Extracellular Matrix Proteins
Concept	Intracellular Signaling Peptides and Proteins
Concept	tau Proteins
Concept	GPI-Linked Proteins
Concept	Adaptor Proteins, Vesicular Transport
Concept	R-SNARE Proteins
Concept	Proto-Oncogene Proteins
Concept	GTPase-Activating Proteins
Concept	Nerve Tissue Proteins
Concept	Tumor Suppressor Proteins
Concept	RNA-Binding Proteins
Concept	Intercellular Signaling Peptides and Proteins
Concept	Repressor Proteins
Concept	HSP90 Heat-Shock Proteins
Concept	Proto-Oncogene Proteins c-akt
Concept	Proteins
Concept	Microtubule-Associated Proteins
Concept	Munc18 Proteins
Concept	Cholesterol Ester Transfer Proteins
Academic Article	TDP-43 pathology, cognitive decline, and dementia in old age.
Academic Article	Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Academic Article	Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.
Academic Article	Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Academic Article	Cognitive reserve, presynaptic proteins and dementia in the elderly.
Academic Article	Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Academic Article	Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Academic Article	Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.
Academic Article	Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease.
Academic Article	The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Academic Article	A common polymorphism near PER1 and the timing of human behavioral rhythms.
Academic Article	Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
Academic Article	The significance of Pin1 in the development of Alzheimer's disease.
Academic Article	Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.
Academic Article	Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Academic Article	Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sample.
Academic Article	Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
Academic Article	Soluble a-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
Academic Article	Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Academic Article	The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-e4 carriers.
Academic Article	REST and stress resistance in ageing and Alzheimer's disease.
Academic Article	Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease.
Academic Article	Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Academic Article	Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
Academic Article	The complex PrP(c)-Fyn couples human oligomeric A? with pathological tau changes in Alzheimer's disease.
Academic Article	Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans.
Academic Article	Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Academic Article	Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Academic Article	Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
Academic Article	Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease.
Academic Article	Alzheimer's disease: Unique markers for diagnosis & new treatment modalities.
Academic Article	Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Academic Article	Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease.
Academic Article	Temporal course of neurodegenerative effects on cognition in old age.
Academic Article	Interaction of transactive response DNA binding protein 43 with nuclear factor ?B in mild cognitive impairment with episodic memory deficits.
Academic Article	PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and A?.
Academic Article	Mild cognitive impairment: is it Alzheimer's disease or not?
Academic Article	Temporal course and pathologic basis of unawareness of memory loss in dementia.
Academic Article	Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology.
Academic Article	GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Academic Article	Education modifies the association of amyloid but not tangles with cognitive function.
Academic Article	Decreases in soluble alpha-synuclein in frontal cortex correlate with cognitive decline in the elderly.
Academic Article	Life-span cognitive activity, neuropathologic burden, and cognitive aging.
Academic Article	Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.
Academic Article	The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
Academic Article	A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers.
Academic Article	Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Academic Article	NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
Academic Article	Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease.
Academic Article	Relation of neuropathology to cognition in persons without cognitive impairment.
Academic Article	Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Academic Article	The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Academic Article	Association of APOE with tau-tangle pathology with and without ?-amyloid.
Academic Article	A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
Academic Article	Life extension factor klotho enhances cognition.
Academic Article	Cerebrospinal fluid tau cleaved by caspase-6 reflects brain levels and cognition in aging and Alzheimer disease.
Academic Article	Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation.
Academic Article	Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues.
Academic Article	Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.
Academic Article	The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease.
Academic Article	GSK3? Interactions with Amyloid Genes: An Autopsy Verification and Extension.
Academic Article	The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Academic Article	Activation of caspase-6 in aging and mild cognitive impairment.
Academic Article	Author Response.
Academic Article	Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense?oligonucleotides.
Academic Article	Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Academic Article	Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease.
Academic Article	Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
Academic Article	Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Academic Article	A novel Alzheimer disease locus located near the gene encoding tau protein.
Academic Article	miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Academic Article	Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.
Academic Article	TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
Academic Article	Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Academic Article	Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
Academic Article	Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology.
Academic Article	An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Academic Article	Novel genetic loci associated with hippocampal volume.
Academic Article	TOMM40'523 variant and cognitive decline in older persons with APOE e3/3 genotype.
Academic Article	Association of Neuropathological Markers in the Parietal Cortex With Antemortem Cognitive Function in Persons With Mild Cognitive Impairment and Alzheimer Disease.
Academic Article	Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Academic Article	Genetic epistasis regulates amyloid deposition in resilient aging.
Academic Article	Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
Academic Article	Selective lowering of synapsins induced by oligomeric a-synuclein exacerbates memory deficits.
Academic Article	Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Academic Article	Soluble Conformers of A? and Tau Alter Selective Proteins Governing Axonal Transport.
Academic Article	Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.
Academic Article	Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
Academic Article	Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
Academic Article	Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
Academic Article	APOE e4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
Academic Article	Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Academic Article	Age and the association of dementia-related pathology with trajectories of cognitive decline.
Academic Article	Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
Academic Article	Genetic influence of plasma homocysteine on Alzheimer's disease.
Academic Article	Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Academic Article	Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.
Academic Article	Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Academic Article	Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.
Academic Article	Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of?Selective Neuronal Vulnerability.
Academic Article	Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.
Academic Article	Neurodegenerative disease and cognitive retest learning.
Academic Article	Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Academic Article	Integrated biology approach reveals molecular and pathological interactions among Alzheimer's A?42, Tau, TREM2, and TYROBP in Drosophila models.
Academic Article	Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples.
Academic Article	Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
Academic Article	TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.
Academic Article	Functional links between A? toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Academic Article	Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Academic Article	A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Academic Article	Tau Activates Transposable Elements in Alzheimer's Disease.
Academic Article	Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Academic Article	Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Academic Article	Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
Academic Article	The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Academic Article	Sex differences in Alzheimer's disease and common neuropathologies of aging.
Academic Article	Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A? and TAU proteostasis.
Academic Article	In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.
Academic Article	Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Academic Article	Physical activity, common brain pathologies, and cognition in community-dwelling older adults.
Academic Article	Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
Academic Article	Disentangling the genetics of lean mass.
Academic Article	Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.
Academic Article	Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
Academic Article	Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons.
Academic Article	Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
Academic Article	CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Academic Article	Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons.
Academic Article	cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Academic Article	Neuropsychological latent classes at enrollment and postmortem neuropathology.
Academic Article	Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline.
Academic Article	Sex differences in the genetic predictors of Alzheimer's pathology.
Academic Article	Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Academic Article	Regulation of lifespan by neural excitation and REST.
Academic Article	The synaptic pathology of cognitive life?.
Academic Article	Quantitative Assessment of Pathological Tau Burden in Essential Tremor: A Postmortem Study.
Academic Article	Shared Causal Paths underlying Alzheimer's dementia and Type 2 Diabetes.
Academic Article	Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Academic Article	Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
Academic Article	Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
Academic Article	Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
Academic Article	Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.
Academic Article	BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
Academic Article	Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218.
Academic Article	Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Academic Article	Recombinant tissue-type plasminogen activator versus a novel dosing regimen of urokinase in acute pulmonary embolism: a randomized controlled multicenter trial.
Academic Article	Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
Academic Article	Association of Low Systolic Blood Pressure with Postmortem Amyloid-? and Tau.
Academic Article	A cortical immune network map identifies distinct microglial transcriptional programs associated with ?-amyloid and Tau pathologies.
Academic Article	Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
Academic Article	A? (Amyloid Beta) and Tau Tangle Pathology Modifies the Association Between Small Vessel Disease and Cortical Microinfarcts.
Academic Article	TOMM40-APOE haplotypes are associated with cognitive decline in non-demented Blacks.
Academic Article	Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
Academic Article	Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons.
Academic Article	Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer's disease.
Academic Article	Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
Academic Article	Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer's disease.
Academic Article	Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Academic Article	Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
Academic Article	Tripartite Relationship Among Synaptic, Amyloid, and Tau Proteins: An In Vivo and Postmortem Study.
Academic Article	Cortical proteins may provide motor resilience in older adults.
Academic Article	Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.
Academic Article	A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
Academic Article	Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
Academic Article	Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Academic Article	Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE e2 protective effect in Alzheimer disease.
Academic Article	BMI1 is associated with CS8F amyloid-? and rates of cognitive decline in Alzheimer's disease.
Academic Article	Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
Academic Article	Role of Retinoid X Receptors (RXRs) and dietary vitamin A in Alzheimer's disease: Evidence from clinicopathological and preclinical studies.
Academic Article	Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults.
Academic Article	Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
Academic Article	Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
Academic Article	Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias.
Academic Article	Association of small vessel disease with tau pathology.
Academic Article	Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ?2 for Alzheimer's disease.
Academic Article	Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults.
Academic Article	Progranulin mutations in clinical and neuropathological Alzheimer's disease.
Academic Article	Identification of the A?37/42 peptide ratio in CSF as an improved A? biomarker for Alzheimer's disease.
Academic Article	Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons.
Academic Article	Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults.
Academic Article	Pelargonidin and Berry Intake Association with Alzheimer's Disease Neuropathology: A Community-Based Study.
Academic Article	Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation.
Concept	CELF Proteins
Concept	ADAMTS Proteins

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Proteins