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Search Results to David A. Bennett

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Item TypeName
Concept Genome-Wide Association Study
Academic Article Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
Academic Article GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Academic Article Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Academic Article Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Academic Article Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Academic Article GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
Academic Article Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
Academic Article Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
Academic Article Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Academic Article Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
Academic Article Genome-wide chromatin state transitions associated with developmental and environmental cues.
Academic Article Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
Academic Article Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Academic Article Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Academic Article ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Academic Article Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
Academic Article Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
Academic Article Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Academic Article A genome-wide association study of depressive symptoms.
Academic Article Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Academic Article Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Academic Article Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Academic Article Common variants at 12q14 and 12q24 are associated with hippocampal volume.
Academic Article Genome-wide association study identifies 74 loci associated with educational attainment.
Academic Article A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline.
Academic Article GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Academic Article Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
Academic Article A genome-wide association study of aging.
Academic Article New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Academic Article Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.
Academic Article Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
Academic Article Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Academic Article The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Academic Article Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.
Academic Article Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Academic Article Charting a dynamic DNA methylation landscape of the human genome.
Academic Article Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.
Academic Article Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.
Academic Article Epigenomics of Alzheimer's disease.
Academic Article Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Academic Article A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
Academic Article Personality Polygenes, Positive Affect, and Life Satisfaction.
Academic Article GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
Academic Article Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.
Academic Article Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.
Academic Article The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
Academic Article Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
Academic Article Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Academic Article Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Academic Article FASTKD2 is associated with memory and hippocampal structure in older adults.
Academic Article Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
Academic Article A novel Alzheimer disease locus located near the gene encoding tau protein.
Academic Article GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Academic Article Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.
Academic Article Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.
Academic Article Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Academic Article Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Academic Article Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Academic Article Differential transcriptome expression in human nucleus accumbens as a function of loneliness.
Academic Article An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Academic Article The complex genetics of gait speed: genome-wide meta-analysis approach.
Academic Article Novel genetic loci associated with hippocampal volume.
Academic Article Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Academic Article Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
Academic Article Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
Academic Article Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
Academic Article Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Academic Article An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
Academic Article Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Academic Article A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Academic Article A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Academic Article Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.
Academic Article Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Academic Article Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
Academic Article Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Academic Article Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
Academic Article Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
Academic Article Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aß and TAU proteostasis.
Academic Article Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Academic Article Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
Academic Article Disentangling the genetics of lean mass.
Academic Article Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aß, tau, immunity and lipid processing.
Academic Article Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria.
Academic Article CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Academic Article TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
Academic Article A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
Academic Article Sex differences in the genetic predictors of Alzheimer's pathology.
Academic Article Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults.
Academic Article Genetic architecture of subcortical brain structures in 38,851 individuals.
Academic Article Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
Academic Article Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.
Academic Article Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.
Academic Article Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
Academic Article Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218.
Academic Article Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Academic Article Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
Academic Article Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
Academic Article Cerebral small vessel disease genomics and its implications across the lifespan.
Academic Article Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Academic Article Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
Academic Article Genetic control of the human brain proteome.
Academic Article Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
Academic Article Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction.
Academic Article Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Academic Article Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
Academic Article A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
Academic Article Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
Academic Article A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer's disease.

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