| Item Type | Name |
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Concept
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Genome, Human
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Concept
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Genome-Wide Association Study
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Concept
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Genome
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Academic Article
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Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
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Academic Article
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GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
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Academic Article
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Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
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Academic Article
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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
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Academic Article
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Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
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Academic Article
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GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
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Academic Article
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Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
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Academic Article
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Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
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Academic Article
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Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
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Academic Article
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Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
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Academic Article
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Genome-wide chromatin state transitions associated with developmental and environmental cues.
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Academic Article
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Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
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Academic Article
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Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
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Academic Article
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Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
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Academic Article
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ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
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Academic Article
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Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
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Academic Article
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Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
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Academic Article
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Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
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Academic Article
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A genome-wide association study of depressive symptoms.
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Academic Article
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Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
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Academic Article
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Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
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Academic Article
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Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
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Academic Article
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Common variants at 12q14 and 12q24 are associated with hippocampal volume.
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Academic Article
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Genome-wide association study identifies 74 loci associated with educational attainment.
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Academic Article
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A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline.
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Academic Article
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GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
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Academic Article
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Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
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Academic Article
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A genome-wide association study of aging.
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Academic Article
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
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Academic Article
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Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.
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Academic Article
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Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
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Academic Article
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Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
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Academic Article
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The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
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Academic Article
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Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.
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Academic Article
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Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
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Academic Article
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Charting a dynamic DNA methylation landscape of the human genome.
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Academic Article
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Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.
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Academic Article
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Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.
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Academic Article
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Epigenomics of Alzheimer's disease.
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Academic Article
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Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
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Academic Article
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A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
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Academic Article
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Personality Polygenes, Positive Affect, and Life Satisfaction.
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Academic Article
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GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
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Academic Article
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Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.
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Academic Article
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Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.
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Academic Article
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The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
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Academic Article
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Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
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Academic Article
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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
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Academic Article
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Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
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Academic Article
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FASTKD2 is associated with memory and hippocampal structure in older adults.
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Academic Article
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Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
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Academic Article
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A novel Alzheimer disease locus located near the gene encoding tau protein.
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Academic Article
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GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
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Academic Article
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Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.
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Academic Article
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Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.
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Academic Article
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Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
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Academic Article
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Gene expression elucidates functional impact of polygenic risk for schizophrenia.
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Academic Article
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Novel genetic loci underlying human intracranial volume identified through genome-wide association.
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Academic Article
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Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
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Academic Article
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Differential transcriptome expression in human nucleus accumbens as a function of loneliness.
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Academic Article
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An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
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Academic Article
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The complex genetics of gait speed: genome-wide meta-analysis approach.
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Academic Article
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A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
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Academic Article
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Novel genetic loci associated with hippocampal volume.
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Academic Article
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Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
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Academic Article
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Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
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Academic Article
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Correction: The complex genetics of gait speed: genome-wide meta-analysis approach.
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Academic Article
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Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
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Academic Article
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Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
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Academic Article
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Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
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Academic Article
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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
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Academic Article
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Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
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Academic Article
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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
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Academic Article
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A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
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Academic Article
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Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.
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Academic Article
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Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
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Academic Article
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Integrated biology approach reveals molecular and pathological interactions among Alzheimer's A?42, Tau, TREM2, and TYROBP in Drosophila models.
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Academic Article
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Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
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Academic Article
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Sex-specific genetic predictors of Alzheimer's disease biomarkers.
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Academic Article
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A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
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Academic Article
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Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
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Academic Article
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Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
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Academic Article
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Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A? and TAU proteostasis.
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Academic Article
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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
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Academic Article
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Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
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Academic Article
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Disentangling the genetics of lean mass.
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Academic Article
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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing.
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Academic Article
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Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria.
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Academic Article
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CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
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Academic Article
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TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
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Academic Article
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A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
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Academic Article
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Somatic mosaicism of sex chromosomes in the blood and brain.
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Academic Article
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Sex differences in the genetic predictors of Alzheimer's pathology.
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Academic Article
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Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults.
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Academic Article
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Genetic architecture of subcortical brain structures in 38,851 individuals.
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Academic Article
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Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
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Academic Article
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Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.
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Academic Article
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Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.
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Academic Article
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Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
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Academic Article
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Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218.
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Academic Article
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Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
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Academic Article
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Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
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Academic Article
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Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
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Academic Article
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Cerebral small vessel disease genomics and its implications across the lifespan.
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Academic Article
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Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
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Academic Article
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Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
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Academic Article
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Genetic control of the human brain proteome.
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Academic Article
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Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
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Academic Article
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Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction.
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Academic Article
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Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
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Academic Article
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Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
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Academic Article
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A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
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Academic Article
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Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
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Academic Article
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A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer's disease.
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Academic Article
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Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants.
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Academic Article
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Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation.
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Academic Article
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Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
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Academic Article
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The power of genetic diversity in genome-wide association studies of lipids.
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Academic Article
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Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.
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Academic Article
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Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ?2 for Alzheimer's disease.
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Academic Article
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Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease.
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Academic Article
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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
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Academic Article
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Genotype-phenotype correlation of T-cell subtypes reveals senescent and cytotoxic genes in Alzheimer's disease.
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Academic Article
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Adherence to MIND Diet, Genetic Susceptibility, and Incident Dementia in Three US Cohorts.
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Concept
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Whole Genome Sequencing
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