Item Type | Name |
Concept
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Brain Damage, Chronic
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Concept
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Blood-Brain Barrier
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Concept
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Brain
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Concept
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Brain Diseases
|
Concept
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Brain Stem
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Concept
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Brain Chemistry
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Concept
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Brain Infarction
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Concept
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Brain-Derived Neurotrophic Factor
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Concept
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Brain Mapping
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Academic Article
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Cerebrovascular disease pathology and parkinsonian signs in old age.
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Academic Article
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Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
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Academic Article
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Post-mortem brain pathology is related to declining respiratory function in community-dwelling older adults.
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Academic Article
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Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition.
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Academic Article
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Cerebral amyloid angiopathy pathology and cognitive domains in older persons.
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Academic Article
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NSAID exposure and risk of Alzheimer disease: is timing everything?
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Academic Article
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TDP-43 pathology, cognitive decline, and dementia in old age.
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Academic Article
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Brain pathology contributes to simultaneous change in physical frailty and cognition in old age.
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Academic Article
|
Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation.
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Academic Article
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Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons.
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Academic Article
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GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.
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Academic Article
|
Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.
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Academic Article
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Cognitive reserve, presynaptic proteins and dementia in the elderly.
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Academic Article
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Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment.
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Academic Article
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Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
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Academic Article
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Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease.
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Academic Article
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Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
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Academic Article
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Grey matter correlates of susceptibility to scams in community-dwelling older adults.
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Academic Article
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Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People.
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Academic Article
|
Correlation of amyloid PET ligand florbetapir F 18 binding with A? aggregation and neuritic plaque deposition in postmortem brain tissue.
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Academic Article
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Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies.
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Academic Article
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Mild cognitive impairment.
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Academic Article
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Implicit memory and Alzheimer's disease neuropathology.
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Academic Article
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Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer's disease.
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Academic Article
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Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease.
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Academic Article
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Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age.
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Academic Article
|
Systemic inflammation in non-demented elderly human subjects: brain microstructure and cognition.
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Academic Article
|
Overview and findings from the rush Memory and Aging Project.
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Academic Article
|
Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
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Academic Article
|
Ex vivo T2 relaxation: associations with age-related neuropathology and cognition.
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Academic Article
|
Mixed pathology is more likely in black than white decedents with Alzheimer dementia.
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Academic Article
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Association of brain pathology with the progression of frailty in older adults.
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Academic Article
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Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
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Academic Article
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Effect of common neuropathologies on progression of late life cognitive impairment.
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Academic Article
|
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
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Academic Article
|
The significance of Pin1 in the development of Alzheimer's disease.
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Academic Article
|
Lewy bodies and olfactory dysfunction in old age.
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Academic Article
|
Neural intrinsic connectivity networks associated with risk aversion in old age.
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Academic Article
|
Cognitive leisure activities, but not watching TV, for future brain benefits.
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Academic Article
|
Novel method to quantify neuropil threads in brains from elders with or without cognitive impairment.
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Academic Article
|
Association of Seafood Consumption, Brain Mercury Level, and APOE e4 Status With Brain Neuropathology in Older Adults.
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Academic Article
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Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
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Academic Article
|
Loneliness and risk of Alzheimer disease.
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Academic Article
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Cognitive activity, cognitive function, and brain diffusion characteristics in old age.
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Academic Article
|
The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort.
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Academic Article
|
REST and stress resistance in ageing and Alzheimer's disease.
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Academic Article
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Postmortem indices linking risk factors to cognition: results from the Religious Order Study and the Memory and Aging Project.
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Academic Article
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Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease.
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Academic Article
|
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
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Academic Article
|
Statins, incident Alzheimer disease, change in cognitive function, and neuropathology.
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Academic Article
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Neurodegenerative basis of age-related cognitive decline.
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Academic Article
|
Terminal decline in motor function.
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Academic Article
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Education modifies the relation of AD pathology to level of cognitive function in older persons.
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Academic Article
|
Much of late life cognitive decline is not due to common neurodegenerative pathologies.
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Academic Article
|
The association of magnetic resonance imaging measures with cognitive function in a biracial population sample.
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Academic Article
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Financial literacy is associated with medial brain region functional connectivity in old age.
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Academic Article
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Selected findings from the Religious Orders Study and Rush Memory and Aging Project.
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Academic Article
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Regional brain cortical thinning and systemic inflammation in older persons without dementia.
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Academic Article
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Microvascular brain pathology and late-life motor impairment.
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Academic Article
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Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles.
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Academic Article
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The relationship between cerebral Alzheimer's disease pathology and odour identification in old age.
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Academic Article
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Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.
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Academic Article
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Functional connectivity networks associated with chronic musculoskeletal pain in old age.
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Academic Article
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Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease.
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Academic Article
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Late-life depression is not associated with dementia-related pathology.
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Academic Article
|
Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment.
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Academic Article
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Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
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Academic Article
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Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease.
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Academic Article
|
Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons.
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Academic Article
|
Aging effects on memory encoding in the frontal lobes.
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Academic Article
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The neuropathology of probable Alzheimer disease and mild cognitive impairment.
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Academic Article
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Response to Letter Regarding Article, "Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People".
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Academic Article
|
Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease.
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Academic Article
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Relation of cerebral infarctions to dementia and cognitive function in older persons.
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Academic Article
|
Ex vivo MR volumetry of human brain hemispheres.
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Academic Article
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Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.
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Academic Article
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Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials.
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Academic Article
|
Genome-wide association study identifies 74 loci associated with educational attainment.
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Academic Article
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CR1 is associated with amyloid plaque burden and age-related cognitive decline.
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Academic Article
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Assessment of cognitive decline in old age with brief tests amenable to telephone administration.
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Academic Article
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Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
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Academic Article
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Financial literacy is associated with white matter integrity in old age.
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Academic Article
|
a-Synuclein pathology accumulates in sacral spinal visceral sensory pathways.
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Academic Article
|
PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and A?.
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Academic Article
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Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older persons.
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Academic Article
|
Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA.
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Academic Article
|
Brain tocopherols related to Alzheimer's disease neuropathology in humans.
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Academic Article
|
Residual decline in cognition after adjustment for common neuropathologic conditions.
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Academic Article
|
Plasma and brain fatty acid profiles in mild cognitive impairment and Alzheimer's disease.
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Academic Article
|
Mild cognitive impairment: is it Alzheimer's disease or not?
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Academic Article
|
Patterns of focal gray matter atrophy are associated with bradykinesia and gait disturbances in older adults.
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Academic Article
|
Temporal course and pathologic basis of unawareness of memory loss in dementia.
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Academic Article
|
Cognitive and social lifestyle: links with neuropathology and cognition in late life.
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Academic Article
|
A 2-process model for neuropathology of Alzheimer's disease.
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Academic Article
|
Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.
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Academic Article
|
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
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Academic Article
|
Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions.
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Academic Article
|
Sex differences in the clinical manifestations of Alzheimer disease pathology.
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Academic Article
|
Mixed brain pathologies account for most dementia cases in community-dwelling older persons.
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Academic Article
|
Associations of cerebrovascular and Alzheimer's disease pathology with brain atrophy.
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Academic Article
|
Loss of basic lexical knowledge in old age.
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Academic Article
|
The natural history of cognitive decline in Alzheimer's disease.
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Academic Article
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Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment.
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Academic Article
|
Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study.
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Academic Article
|
The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia.
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Academic Article
|
Where vascular meets neurodegenerative disease.
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Academic Article
|
Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1.
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Academic Article
|
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
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Academic Article
|
Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.
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Academic Article
|
The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
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Academic Article
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A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers.
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Academic Article
|
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
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Academic Article
|
Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.
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Academic Article
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Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project.
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Academic Article
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Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age.
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Academic Article
|
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment.
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Academic Article
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Relation of neuropathology to cognition in persons without cognitive impairment.
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Academic Article
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Epigenomics of Alzheimer's disease.
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Academic Article
|
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
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Academic Article
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Association of APOE with tau-tangle pathology with and without ?-amyloid.
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Academic Article
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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
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Academic Article
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Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition.
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Academic Article
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Cerebrospinal fluid tau cleaved by caspase-6 reflects brain levels and cognition in aging and Alzheimer disease.
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Academic Article
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Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study.
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Academic Article
|
Very low levels of education and cognitive reserve: a clinicopathologic study.
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Academic Article
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Functional connectivity variations in mild cognitive impairment: associations with cognitive function.
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Academic Article
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Relation of antiphospholipid antibodies to postmortem brain infarcts in older people.
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Academic Article
|
Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults.
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Academic Article
|
Physical frailty in older persons is associated with Alzheimer disease pathology.
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Academic Article
|
Neural reserve, neuronal density in the locus ceruleus, and cognitive decline.
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Academic Article
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Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.
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Academic Article
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Brain amyloid-? oligomers in ageing and Alzheimer's disease.
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Academic Article
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Update on mild cognitive impairment.
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Academic Article
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GSK3? Interactions with Amyloid Genes: An Autopsy Verification and Extension.
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Academic Article
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Chronic distress, age-related neuropathology, and late-life dementia.
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Academic Article
|
The amyloid pathology progresses in a neurotransmitter-specific manner.
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Academic Article
|
Overview and findings from the religious orders study.
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Academic Article
|
Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study.
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Academic Article
|
Neuropathologic correlates of regional brain volumes in a community cohort of older adults.
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Academic Article
|
Vulnerability to stress, anxiety, and development of dementia in old age.
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Academic Article
|
Genetic variants in Alzheimer disease - molecular and brain network approaches.
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Academic Article
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Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense?oligonucleotides.
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Academic Article
|
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
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Academic Article
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Age-associated reduction of asymmetry in prefrontal function and preservation of conceptual repetition priming.
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Academic Article
|
Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings.
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Academic Article
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Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.
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Academic Article
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Kidney function is associated with the rate of cognitive decline in the elderly.
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Academic Article
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The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
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Academic Article
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Clinical correlates of high signal lesions on magnetic resonance imaging in Alzheimer's disease.
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Academic Article
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Clinical diagnosis of Binswanger's disease.
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Academic Article
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White matter changes: neurobehavioral manifestations of Binswanger's disease and clinical correlates in Alzheimer's disease.
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Academic Article
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Alzheimer's disease: in vivo detection of differential vulnerability of brain regions.
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Academic Article
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Terminal dedifferentiation of cognitive abilities.
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Academic Article
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The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts.
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Academic Article
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Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.
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Academic Article
|
Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.
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Academic Article
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Gene expression elucidates functional impact of polygenic risk for schizophrenia.
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Academic Article
|
TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
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Academic Article
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Novel genetic loci underlying human intracranial volume identified through genome-wide association.
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Academic Article
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Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology.
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Academic Article
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Differential transcriptome expression in human nucleus accumbens as a function of loneliness.
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Academic Article
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Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
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Academic Article
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A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
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Academic Article
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Risk of incident clinical diagnosis of Alzheimer's disease-type dementia?attributable to pathology-confirmed vascular disease.
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Academic Article
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Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology.
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Academic Article
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Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline.
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Academic Article
|
TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD.
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Academic Article
|
A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
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Academic Article
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Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery.
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Academic Article
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Genetic epistasis regulates amyloid deposition in resilient aging.
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Academic Article
|
Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
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Academic Article
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Selective lowering of synapsins induced by oligomeric a-synuclein exacerbates memory deficits.
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Academic Article
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Reduced pCREB in Alzheimer's disease prefrontal cortex is reflected in peripheral blood mononuclear cells.
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Academic Article
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Soluble Conformers of A? and Tau Alter Selective Proteins Governing Axonal Transport.
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Academic Article
|
Traumatic brain injury may not increase the risk of Alzheimer disease.
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Academic Article
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Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
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Academic Article
|
How Does Psychosocial Behavior Contribute to Cognitive Health in Old Age?
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Academic Article
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Alzheimer's brains show inter-related changes in RNA and lipid metabolism.
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Academic Article
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Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
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Academic Article
|
Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.
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Academic Article
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An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
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Academic Article
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Spinal Arteriolosclerosis Is Common in Older Adults and Associated With Parkinsonism.
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Academic Article
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Spinal Lewy body pathology in older adults without an antemortem diagnosis of Parkinson's disease.
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Academic Article
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Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease.
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Academic Article
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Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
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Academic Article
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Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
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Academic Article
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Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.
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Academic Article
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Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
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Academic Article
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Person-specific contribution of neuropathologies to cognitive loss in old age.
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Academic Article
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Ex-vivo quantitative susceptibility mapping of human brain hemispheres.
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Academic Article
|
Financial and Health Literacy Predict Incident Alzheimer's Disease Dementia and Pathology.
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Academic Article
|
Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.
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Academic Article
|
Motor axonal regeneration after partial and complete spinal cord transection.
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Academic Article
|
Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells.
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Academic Article
|
Integrated biology approach reveals molecular and pathological interactions among Alzheimer's A?42, Tau, TREM2, and TYROBP in Drosophila models.
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Academic Article
|
Microscale fractionation facilitates detection of differentially expressed proteins in Alzheimer's disease brain samples.
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Academic Article
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Biomarker discovery and analysis platform: application to Alzheimer's disease.
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Academic Article
|
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
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Academic Article
|
Brain pathology is related to total daily physical activity in older adults.
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Academic Article
|
APOE e2e4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.
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Academic Article
|
Sexual dimorphism in predisposition to Alzheimer's disease.
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Academic Article
|
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
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Academic Article
|
Tau Activates Transposable Elements in Alzheimer's Disease.
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Academic Article
|
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
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Academic Article
|
Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults.
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Academic Article
|
Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics.
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Academic Article
|
Watershed microinfarct pathology and cognition in older persons.
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Academic Article
|
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
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Academic Article
|
White matter correlates of temporal discounting in older adults.
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Academic Article
|
Late-life blood pressure association with cerebrovascular and Alzheimer disease pathology.
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Academic Article
|
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
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Academic Article
|
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
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Academic Article
|
Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline.
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Academic Article
|
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
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Academic Article
|
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
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Academic Article
|
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
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Academic Article
|
Sex differences in Alzheimer's disease and common neuropathologies of aging.
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Academic Article
|
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in A? and TAU proteostasis.
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Academic Article
|
Spinal motor neurons and motor function in older adults.
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Academic Article
|
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
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Academic Article
|
Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain.
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Academic Article
|
Physical activity, common brain pathologies, and cognition in community-dwelling older adults.
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Academic Article
|
DNA methylation variability in Alzheimer's disease.
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Academic Article
|
Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
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Academic Article
|
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
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Academic Article
|
Education and cognitive reserve in old age.
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Academic Article
|
Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons.
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Academic Article
|
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
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Academic Article
|
Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer's disease.
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Academic Article
|
Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.
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Academic Article
|
White matter correlates of scam susceptibility in community-dwelling older adults.
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Academic Article
|
Association of Cortical ?-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.
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Academic Article
|
Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria.
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Academic Article
|
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
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Academic Article
|
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
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Academic Article
|
Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease.
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Academic Article
|
Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons.
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Academic Article
|
Association of Lifespan Cognitive Reserve Indicator With Dementia Risk in the Presence of Brain Pathologies.
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Academic Article
|
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
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Academic Article
|
Associations Between Depression, Traumatic Brain Injury, and Cognitively-Defined Late-Onset Alzheimer's Disease Subgroups.
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Academic Article
|
Somatic mosaicism of sex chromosomes in the blood and brain.
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Academic Article
|
Neuropsychological latent classes at enrollment and postmortem neuropathology.
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Academic Article
|
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain.
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Academic Article
|
Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline.
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Academic Article
|
Sex differences in the genetic predictors of Alzheimer's pathology.
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Academic Article
|
Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
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Academic Article
|
Common age-related neuropathologies and yearly variability in cognition.
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Academic Article
|
Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults.
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Academic Article
|
Interaction between the progression of Alzheimer's disease and fractal degradation.
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Academic Article
|
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
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Academic Article
|
Regulation of lifespan by neural excitation and REST.
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Academic Article
|
Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis.
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Academic Article
|
Genetic architecture of subcortical brain structures in 38,851 individuals.
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Academic Article
|
Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices.
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Academic Article
|
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
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Academic Article
|
Rate of brain aging and APOE e4 are synergistic risk factors for Alzheimer's disease.
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Academic Article
|
Brain mural cell loss in the parietal cortex in Alzheimer's disease correlates with cognitive decline and TDP-43 pathology.
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Academic Article
|
Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts.
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Academic Article
|
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
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Academic Article
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Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
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Academic Article
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The Health Equity Through Aging Research And Discussion (HEARD) Study: A Proposed Two-Phase Sequential Mixed-Methods Research Design To Understand Barriers And Facilitators Of Brain Donation Among Diverse Older Adults.
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3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.
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Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
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Academic Article
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Corrigendum to brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis [Neurobiology of Aging Volume 86, February 2020, Pages 123-133].
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Academic Article
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Total daily physical activity, brain pathologies, and parkinsonism in older adults.
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Academic Article
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Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
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Academic Article
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Associations Between Cardiovascular Risk, Structural Brain Changes, and Cognitive Decline.
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Academic Article
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Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
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Academic Article
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Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy.
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Academic Article
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Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
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Academic Article
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Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function.
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Academic Article
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Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
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Academic Article
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Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
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Academic Article
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Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.
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Academic Article
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What HIV in the Brain Can Teach Us About SARS-CoV-2 Neurological Complications?
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Academic Article
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Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
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Academic Article
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Self-reported experiences of discrimination in older black adults are associated with insula functional connectivity.
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Academic Article
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Person-Specific Contributions of Brain Pathologies to Progressive Parkinsonism in Older Adults.
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Academic Article
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BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
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Academic Article
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Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults.
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Academic Article
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Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
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Academic Article
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Brain pathologies are associated with both the rate and variability of declining motor function in older adults.
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Academic Article
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Deconvolving the contributions of cell-type heterogeneity on cortical gene expression.
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Academic Article
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Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
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Academic Article
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Brain Renin-Angiotensin System at the Intersect of Physical and Cognitive Frailty.
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Academic Article
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Association of serial position scores on memory tests and hippocampal-related neuropathologic outcomes.
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Academic Article
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Association of Low Systolic Blood Pressure with Postmortem Amyloid-? and Tau.
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Academic Article
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Perceived Impediments to Completed Brain Autopsies Among Diverse Older Adults Who Have Signed a Uniform Anatomical Gift Act for Brain Donation for Clinical Research.
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Academic Article
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A cortical immune network map identifies distinct microglial transcriptional programs associated with ?-amyloid and Tau pathologies.
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Academic Article
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Development and evaluation of a high performance T1-weighted brain template for use in studies on older adults.
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Academic Article
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Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men.
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Academic Article
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Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
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Academic Article
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A? (Amyloid Beta) and Tau Tangle Pathology Modifies the Association Between Small Vessel Disease and Cortical Microinfarcts.
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Academic Article
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Genetic control of the human brain proteome.
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Academic Article
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Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons.
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Academic Article
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Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer's disease.
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Academic Article
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Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample.
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Academic Article
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Systemic brain derived neurotrophic factor but not intestinal barrier integrity is associated with cognitive decline and incident Alzheimer's disease.
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Academic Article
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To what degree is late life cognitive decline driven by age-related neuropathologies?
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Academic Article
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Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline.
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Academic Article
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Late-Life Vascular Risk Score in Association With Postmortem Cerebrovascular Disease Brain Pathologies.
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Academic Article
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Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
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Enhancing Top-Down Proteomics of Brain Tissue with FAIMS.
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Academic Article
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Brain insulin signaling and cerebrovascular disease in human postmortem brain.
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Academic Article
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The "cognitive clock": A novel indicator of brain health.
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Academic Article
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Abnormal brain cholesterol homeostasis in Alzheimer's disease-a targeted metabolomic and transcriptomic study.
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Academic Article
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The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
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Academic Article
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Cognitive and brain cytokine profile of non-demented individuals with cerebral amyloid-beta deposition.
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Academic Article
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Physical activity, brain tissue microstructure, and cognition in older adults.
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Academic Article
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A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer's disease.
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Academic Article
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Association of cardiovascular risk burden with risk of dementia and brain pathologies: A population-based cohort study.
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Academic Article
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ARTS: A novel In-vivo classifier of arteriolosclerosis for the older adult brain.
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Academic Article
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MIND Diet, Common Brain Pathologies, and Cognition in Community-Dwelling Older Adults.
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Academic Article
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Association of Amyloid-? Pathology with Decision Making and Scam Susceptibility.
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Academic Article
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EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE e4 ON ALZHEIMER'S DISEASE RISK IN HUMANS.
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Academic Article
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Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE e2 protective effect in Alzheimer disease.
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Academic Article
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Influence of Cognitive Reserve on Cognitive Trajectories: Role of Brain Pathologies.
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Academic Article
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Pulmonary function is associated with cognitive decline and structural brain differences.
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Academic Article
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Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline.
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Academic Article
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A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology.
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Academic Article
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Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
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Academic Article
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Reducing Your Risk of Alzheimer's Dementia: Building a Better Brain as We Age.
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Brain ?-Amyloid Links the Association of Change in Body Mass Index With Cognitive Decline in Community-Dwelling Older Adults.
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Academic Article
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Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging.
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Academic Article
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Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain.
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Academic Article
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A brain proteomic signature of incipient Alzheimer's disease in young APOE e4 carriers identifies novel drug targets.
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Academic Article
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Human Brain and Blood N-Glycome Profiling in Alzheimer's Disease and Alzheimer's Disease-Related Dementias.
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Academic Article
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Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults.
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Academic Article
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Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
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Academic Article
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Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
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Academic Article
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Higher Angiotensin II Type 1 Receptor Levels and Activity in the Postmortem Brains of Older Persons with Alzheimer's Dementia.
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Academic Article
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Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias.
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Academic Article
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Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia.
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Academic Article
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Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain.
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Academic Article
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Late-life physical activity relates to brain tissue synaptic integrity markers in older adults.
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Academic Article
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Association of small vessel disease with tau pathology.
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Academic Article
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Co-expression network analysis of frontal cortex during the progression of Alzheimer's disease.
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Academic Article
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Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
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Academic Article
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Inferring protein expression changes from mRNA in Alzheimer's dementia using deep neural networks.
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Academic Article
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Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
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Academic Article
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Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease.
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Academic Article
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Poor pulmonary function is associated with mild cognitive impairment, its progression to dementia, and brain pathologies: A community-based cohort study.
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Academic Article
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Analysis and Comparison of Mouse and Human Brain Gangliosides via Two-Stage Matching of MS/MS Spectra.
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Academic Article
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Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults.
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Academic Article
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Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults.
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Academic Article
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Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons.
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Academic Article
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Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults.
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Academic Article
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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
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Academic Article
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Mitochondrial respiratory chain protein co-regulation in the human brain.
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Academic Article
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FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease.
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Academic Article
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Neurodegenerative and Cerebrovascular Brain Pathologies Are Differentially Associated With Declining Grip Strength and Gait In Older Adults.
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Academic Article
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Pelargonidin and Berry Intake Association with Alzheimer's Disease Neuropathology: A Community-Based Study.
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Academic Article
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Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation.
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Academic Article
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The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease.
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Academic Article
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Development of high quality T1-weighted and diffusion tensor templates of the older adult brain in a common space.
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Concept
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Brain Injuries, Traumatic
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