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Search Results to John Sandy

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One or more keywords matched the following items that are connected to Sandy, John

Item TypeName
Concept Matrix Metalloproteinase Inhibitors
Concept Matrix Metalloproteinase 1
Concept Matrix Metalloproteinase 3
Concept Matrix Metalloproteinase 13
Academic Article ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.
Academic Article Focal cerebral ischemia induces changes in both MMP-13 and aggrecan around individual neurons.
Academic Article Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.
Academic Article Hyaluronan injection in murine osteoarthritis prevents TGFbeta 1-induced synovial neovascularization and fibrosis and maintains articular cartilage integrity by a CD44-dependent mechanism.
Academic Article Inhibition of cartilage degradation and changes in physical properties induced by IL-1beta and retinoic acid using matrix metalloproteinase inhibitors.
Academic Article ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain.
Academic Article Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage.
Academic Article Changes in cartilage composition and physical properties due to stromelysin degradation.

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  • Matrix Metalloproteinase 2