Item Type | Name |
Concept
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Physical Conditioning, Animal
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Concept
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Disease Models, Animal
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Concept
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Animals, Newborn
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Concept
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Animals
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Concept
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Models, Animal
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Academic Article
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Effects of soluble metals on human peri-implant cells.
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Academic Article
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Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models.
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Academic Article
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Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption.
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Academic Article
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Immunomodulation of proteoglycan-induced progressive polyarthritis by leflunomide.
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Academic Article
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Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis.
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Academic Article
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Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases.
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Academic Article
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Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice.
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Academic Article
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Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans.
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Academic Article
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Cartilage proteoglycans as potential autoantigens in humans and in experimental animals.
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Academic Article
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Antigenic profiles of human, bovine and canine articular chondrocytes.
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Academic Article
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Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan.
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Academic Article
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Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology.
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Academic Article
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Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.
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Academic Article
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Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis.
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Academic Article
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A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice.
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Academic Article
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Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis.
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Academic Article
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Interferon-gamma but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma.
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Academic Article
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Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
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Academic Article
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Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
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Academic Article
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The role of adhesion molecules in the development of autoimmune arthritis.
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Academic Article
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Mediators and autopathogenic effector cells in proteoglycan-induced arthritic and clinically asymptomatic BALB/c mice.
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Academic Article
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Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan-induced murine arthritis.
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Academic Article
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Functional assessment of joint use in experimental inflammatory murine arthritis.
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Academic Article
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Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation.
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Academic Article
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Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.
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Academic Article
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Modulation of hyaluronan receptor (CD44) function in vivo in a murine model of rheumatoid arthritis.
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Academic Article
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Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines.
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Academic Article
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Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis.
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Academic Article
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Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis.
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Academic Article
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Adhesion of lymphoid cells to CD44-specific substrata: the consequences of attachment depend on the ligand.
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Academic Article
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Spontaneous thymocyte apoptosis is regulated by a mitochondrion-mediated signaling pathway.
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Academic Article
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A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis.
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Academic Article
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Vitaxin applied molecular evolution.
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Academic Article
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Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease.
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Academic Article
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Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis.
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Academic Article
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Antibody-induced shedding of CD44 from adherent cells is linked to the assembly of the cytoskeleton.
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Academic Article
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Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis.
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Academic Article
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Increased resistance to collagen-induced arthritis in CD44-deficient DBA/1 mice.
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Academic Article
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Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis.
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Academic Article
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Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6.
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Academic Article
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Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice.
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Academic Article
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Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis.
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Academic Article
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IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms.
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Academic Article
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Role of the extracellular and cytoplasmic domains of CD44 in the rolling interaction of lymphoid cells with hyaluronan under physiologic flow.
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Academic Article
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Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci.
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Academic Article
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IL-4 potentiates activated T cell apoptosis via an IL-2-dependent mechanism.
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Academic Article
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Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice.
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Academic Article
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CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis.
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Academic Article
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Sex effect on clinical and immunologic quantitative trait loci in a murine model of rheumatoid arthritis.
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Academic Article
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Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones.
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Academic Article
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Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan.
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Academic Article
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Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics.
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Academic Article
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TSG-6 modulates the interaction between hyaluronan and cell surface CD44.
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Academic Article
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Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis.
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Academic Article
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Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype.
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Academic Article
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Expression of L-selectin, but not CD44, is required for early neutrophil extravasation in antigen-induced arthritis.
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Academic Article
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Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.
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Academic Article
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Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis.
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Academic Article
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Enhanced neutrophil extravasation and rapid progression of proteoglycan-induced arthritis in TSG-6-knockout mice.
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Academic Article
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Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation.
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Academic Article
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A longitudinal study on an autoimmune murine model of ankylosing spondylitis.
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Academic Article
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Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation.
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Academic Article
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Genetic control of experimental spondylarthropathy.
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Academic Article
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Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy.
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Academic Article
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CD44, but not l-selectin, is critically involved in leucocyte migration into the skin in a murine model of allergic dermatitis.
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Academic Article
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T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.
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Academic Article
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Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis.
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Academic Article
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Expression of CD44 and L-selectin in the innate immune system is required for severe joint inflammation in the proteoglycan-induced murine model of rheumatoid arthritis.
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Academic Article
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Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
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Academic Article
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Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice.
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Academic Article
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TSG-6 regulates bone remodeling through inhibition of osteoblastogenesis and osteoclast activation.
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Academic Article
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Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation.
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Academic Article
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Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation.
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Academic Article
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CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis.
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Academic Article
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BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.
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Academic Article
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Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice.
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Academic Article
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Oral glucosamine modulates the response of the liver and lymphocytes of the mesenteric lymph nodes in a papain-induced model of joint damage and repair.
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Academic Article
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The genetic background of ankylosing spondylitis.
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Academic Article
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Modulation of hyaluronan production by CD44 positive glioma cells.
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Academic Article
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IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis.
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Academic Article
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Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.
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Academic Article
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Immunosenescence and its potential modulation: lessons from mouse models.
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Academic Article
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Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice.
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Academic Article
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Osteoarthritis-like damage of cartilage in the temporomandibular joints in mice with autoimmune inflammatory arthritis.
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Academic Article
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Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.
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Academic Article
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Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.
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Academic Article
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TSG-6 protein, a negative regulator of inflammatory arthritis, forms a ternary complex with murine mast cell tryptases and heparin.
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Academic Article
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T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice.
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Academic Article
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Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis.
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Academic Article
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Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family.
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Academic Article
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Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis.
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Academic Article
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Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice.
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Academic Article
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In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis.
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Academic Article
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TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma.
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Academic Article
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Controlled treadmill exercise eliminates chondroid deposits and restores tensile properties in a new murine tendinopathy model.
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Academic Article
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Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6.
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Academic Article
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Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.
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Academic Article
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Genetics of rheumatoid arthritis - a comprehensive review.
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Academic Article
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Pharmacogenetics and pharmacogenomics in rheumatology.
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Academic Article
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The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis.
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Academic Article
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Differentially expressed epigenome modifiers, including aurora kinases A and B, in immune cells in rheumatoid arthritis in humans and mouse models.
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Academic Article
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ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy.
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Academic Article
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Of mice and men: how animal models advance our understanding of T-cell function in RA.
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Academic Article
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Epigenetics in the pathogenesis of rheumatoid arthritis.
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Academic Article
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Proteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritis.
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Academic Article
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Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow.
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Academic Article
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Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis.
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Academic Article
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Enigma of IL-17 and Th17 Cells in Rheumatoid Arthritis and in Autoimmune Animal Models of Arthritis.
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Academic Article
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FTY720 (Gilenya) treatment prevents spontaneous autoimmune myocarditis and dilated cardiomyopathy in transgenic HLA-DQ8-BALB/c mice.
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Academic Article
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Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis.
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Academic Article
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Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance.
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Academic Article
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An epitope-specific DerG-PG70 LEAPS vaccine modulates T cell responses and suppresses arthritis progression in two related murine models of rheumatoid arthritis.
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Academic Article
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Editorial: Ratiometric Optical Imaging of Subclinical Inflammation With a Thrombin-Cleavable Probe: A Future Tool for the In Vivo Visualization of Clinically Silent Synovitis?
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Academic Article
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Amelioration of Autoimmune Arthritis in Mice Treated With the DNA Methyltransferase Inhibitor 5'-Azacytidine.
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Academic Article
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Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase.
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Academic Article
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Restoring the Balance between Pro-Inflammatory and Anti-Inflammatory Cytokines in the Treatment of Rheumatoid Arthritis: New Insights from Animal Models.
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Academic Article
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SHP-1 Protein Tyrosine Phosphatase Affects Early Postnatal Bone Development in Mice.
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Academic Article
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THEMIS increases TCR signaling in CD4+CD8+ thymocytes by inhibiting the activity of the tyrosine phosphatase SHP1.
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