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Nicholson, Daniel
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Nicholson, Daniel
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Concept
Aspartic Acid Endopeptidases
Academic Article
The Alzheimer's ?-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.
Academic Article
Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased A? generation in Alzheimer's disease.
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Endopeptidases