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One or more keywords matched the following properties of Borgia, Jeffrey
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overview Director, Rush University Cancer Center Biorepository. Director, Rush Biomarker Development Core. My Scopus ID is 6602993443. My NIH COMMONS name is JBORGIA. Research Areas: My research is primarily focused on the development of novel diagnostic tests based on ‘Omic’-level profiling of patient specimens and/or mechanistic insights for pathophysiology. As the Director of the Rush Cancer Center Biorepository, I oversee the collection and annotation of patient specimens to support translational research projects and clinical trials that are ongoing in the Rush University Cancer Center. My role as the Director of the Rush Biomarker Development Core permits me to facilitate the administration of ‘state of the art’ services aimed at the discovery and development of novel biomarkers aimed at altering treatment decisions in the clinics, ranging from early cancer detection to personalized treatment selection for patients. Platforms supported include quantitative mass spectrometry and custom Luminex immunoassays that, combined with accompanying laboratory automation and skilled personnel, generate very high-throughput biomarker discovery, assay development (with analytical validation), and routine specimen processing. In response to the global Covid-19 pandemic my laboratory has developed a novel multiplex serological test that has been submitted for FDA approval under the Emergency Use Authorization. This assay quantitatively evaluates an immune response to the SARS-CoV-2 virus, including antibodies associated with viral neutralization. Further, my lab has partnered with Dr. Jeffrey Schneider and Dr. João Mamede to provide a functional assessment of SARS-CoV-2 neutralization through an ‘in house’ developed pseudovirus neutralization assay. My Faculty Profile at Rush University Medical Center: https://www.rushu.rush.edu/faculty/jeffrey-borgia-phd My Laboratory: https://www.rushu.rush.edu/research/departmental-research/cell-molecular-medicine-research/laboratory-jeffrey-borgia-phd My NCBI Bibliography: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40797756/?sort=date&direction=descending My Scopus: https://www.scopus.com/authid/detail.uri?authorId=6602993443 Education: PhD, University of Minnesota, Twin Cities BS, Eckerd College
One or more keywords matched the following items that are connected to Borgia, Jeffrey
Item TypeName
Concept Esophageal Neoplasms
Concept Lung Neoplasms
Concept Early Detection of Cancer
Concept Neoplasm Metastasis
Concept Hematologic Neoplasms
Concept Biomarkers, Tumor
Concept Antigens, Neoplasm
Concept Neoplasms, Experimental
Concept Colorectal Neoplasms
Concept Neoplasm Staging
Concept Drug Resistance, Neoplasm
Concept Neoplasm Transplantation
Concept Tumor Microenvironment
Concept Antibodies, Neoplasm
Concept Tumor Cells, Cultured
Concept Tumor Necrosis Factor-alpha
Concept Neoplasms
Concept Cell Line, Tumor
Concept Neoplasm Recurrence, Local
Concept Neoplasm Invasiveness
Academic Article RNA-Seq and Network Analysis Revealed Interacting Pathways in TGF-?-Treated Lung Cancer Cell Lines.
Academic Article Value of circulating insulin-like growth factor-associated proteins for the detection of stage I non-small cell lung cancer.
Academic Article Evaluation of Plasma miR-21 and miR-152 as Diagnostic Biomarkers for Common Types of Human Cancers.
Academic Article Biomarkers of the insulin-like growth factor pathway predict progression and outcome in lung cancer.
Academic Article A multi-analyte serum test for the detection of non-small cell lung cancer.
Academic Article Development and validation of a plasma biomarker panel for discerning clinical significance of indeterminate pulmonary nodules.
Academic Article Establishment of a multi-analyte serum biomarker panel to identify lymph node metastases in non-small cell lung cancer.
Academic Article Enhancement of a multianalyte serum biomarker panel to identify lymph node metastases in non-small cell lung cancer with circulating autoantibody biomarkers.
Academic Article Metformin exposure is associated with improved progression-free survival in diabetic patients after resection for early-stage non-small cell lung cancer.
Academic Article Circulating angiogenesis biomarkers are associated with disease progression in lung adenocarcinoma.
Academic Article Development of a serum biomarker panel predicting recurrence in stage I non-small cell lung cancer patients.
Academic Article Development of a multiplexed tumor-associated autoantibody-based blood test for the detection of non-small cell lung cancer.
Academic Article Angiogenesis Biomarkers May Be Useful in the Management of Patients With Indeterminate Pulmonary Nodules.
Academic Article Targeting the insulin-like growth factor receptor pathway in lung cancer: problems and pitfalls.
Academic Article Lyn, a Src family kinase, regulates activation of epidermal growth factor receptors in lung adenocarcinoma cells.
Academic Article Rac1-mediated cytoskeleton rearrangements induced by intersectin-1s deficiency promotes lung cancer cell proliferation, migration and metastasis.
Academic Article Differential modulation of human melanoma cell metalloproteinase expression by alpha2beta1 integrin and CD44 triple-helical ligands derived from type IV collagen.
Academic Article Kernelized partial least squares for feature reduction and classification of gene microarray data.
Academic Article All in the family: Clueing into the link between metabolic syndrome and hematologic malignancies.
Academic Article PRMT1 Is a Novel Regulator of Epithelial-Mesenchymal-Transition in Non-small Cell Lung Cancer.
Academic Article Modulation of triple-helical stability and subsequent melanoma cellular responses by single-site substitution of fluoroproline derivatives.
Academic Article Relationships between longitudinal neutrophil to lymphocyte ratios, body weight changes, and overall survival in patients with non-small cell lung cancer.
Academic Article Differential expression of circulating biomarkers of tumor phenotype and outcomes in previously treated non-small cell lung cancer patients receiving erlotinib vs. cytotoxic chemotherapy.
Academic Article Practical and theoretical implications of weight gain in advanced non-small cell lung cancer patients.
Academic Article Serum Biomarkers May Prognosticate Recurrence in Node-Negative, Non-Small Cell Lung Cancers Less Than 4 Centimeters.
Academic Article Global lipidomics identified plasma lipids as novel biomarkers for early detection of lung cancer.
Academic Article Reply.
Academic Article Development of bead based multiplexed immunoassay for evaluation of midkine, syndecan-1, and ANGPTL4 in patient serum.
Academic Article The serum-based VeriStrat? test is associated with proinflammatory reactants and clinical outcome in non-small cell lung cancer patients.
Academic Article Circulating histocompatibility antigen (HLA) gene products may help differentiate benign from malignant indeterminate pulmonary lesions.
Academic Article Global lipidomics reveals two plasma lipids as novel biomarkers for the detection of squamous cell lung cancer: A pilot study.
Academic Article Plasma small ncRNA pair panels as novel biomarkers for early-stage lung adenocarcinoma screening.
Academic Article Evaluation of the impact of cachexia on clinical outcomes in aggressive lymphoma.
Academic Article CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC.
Academic Article Prognostic Significance of Skeletal Muscle Loss During Early Postoperative Period in Elderly Patients with Esophageal Cancer.
Academic Article Theoretical and Practical Implications of Treating Cachexia in Advanced Lung Cancer Patients.
Academic Article Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma.
Academic Article Relationship between circulating tumor-associated autoantibodies and clinical outcomes in advanced-stage NSCLC patients receiving PD-1/-L1 directed immune checkpoint inhibition.
Academic Article Sarcopenia after induction therapy is associated with reduced survival in patients undergoing esophagectomy for locally-advanced esophageal cancer.
Academic Article Neutrophil-to-Lymphocyte Ratio Is a Predictive Biomarker in Patients with Epidermal Growth Factor Receptor (EGFR) Mutated Advanced Non-Small Cell Lung Cancer (NSCLC) Treated with Tyrosine Kinase Inhibitor (TKI) Therapy.
Academic Article A pan-cancer organoid platform for precision medicine.
Academic Article Soluble Urokinase Plasminogen Activator Receptor Is Associated With Subclinical Myocardial Impairment by Speckle Tracking Echocardiography in Lung Cancer Patients.
Academic Article Prolyl Carboxypeptidase Maintains Receptor Tyrosine Kinase Signaling and Is a Potential Therapeutic Target in Triple Negative Breast Cancer.
Academic Article Expression of Immunomodulatory Checkpoint Molecules in Drug-Resistant Neuroblastoma: An Exploratory Study.
Academic Article The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer.
Academic Article Refining colorectal cancer classification and clinical stratification through a single-cell atlas.
Academic Article Development of exploratory algorithms to aid in risk of malignancy prediction of indeterminate pulmonary nodules.
Academic Article The association between thoracic sarcopenia and survival is gender specific in early-stage lung cancer.
Academic Article Development of a Novel Circulating Autoantibody Biomarker Panel for the Identification of Patients with 'Actionable' Pulmonary Nodules.
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  • Neoplasms