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Mikecz, Katalin

One or more keywords matched the following items that are connected to Mikecz, Katalin

Item Type	Name
Concept	Mice, Inbred NOD
Concept	Mice, Inbred AKR
Concept	Mice, Inbred BALB C
Concept	Mice, Inbred C3H
Concept	Mice, Inbred Strains
Concept	Mice, Inbred DBA
Concept	Mice, Inbred C57BL
Academic Article	Knockout of ADAMTS5 does not eliminate cartilage aggrecanase activity but abrogates joint fibrosis and promotes cartilage aggrecan deposition in murine osteoarthritis models.
Academic Article	Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: fibroblast-mediated pathologic bone resorption.
Academic Article	Immunomodulation of proteoglycan-induced progressive polyarthritis by leflunomide.
Academic Article	Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis.
Academic Article	Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases.
Academic Article	Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice.
Academic Article	Cartilage proteoglycans as potential autoantigens in humans and in experimental animals.
Academic Article	Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan.
Academic Article	Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology.
Academic Article	Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.
Academic Article	Mapping of arthritogenic/autoimmune epitopes of cartilage aggrecans in proteoglycan-induced arthritis.
Academic Article	A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice.
Academic Article	Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis.
Academic Article	Interferon-gamma but not granulocyte/macrophage colony-stimulating factor augments proteoglycan presentation by synovial cells and chondrocytes to an autopathogenic T cell hybridoma.
Academic Article	Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
Academic Article	Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.
Academic Article	Mediators and autopathogenic effector cells in proteoglycan-induced arthritic and clinically asymptomatic BALB/c mice.
Academic Article	Migration and homing of lymphocytes to lymphoid and synovial tissues in proteoglycan-induced murine arthritis.
Academic Article	Functional assessment of joint use in experimental inflammatory murine arthritis.
Academic Article	Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation.
Academic Article	Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.
Academic Article	Modulation of hyaluronan receptor (CD44) function in vivo in a murine model of rheumatoid arthritis.
Academic Article	Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines.
Academic Article	Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis.
Academic Article	Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis.
Academic Article	Spontaneous thymocyte apoptosis is regulated by a mitochondrion-mediated signaling pathway.
Academic Article	A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis.
Academic Article	Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice: evidence of genetically acquired resistance to autoimmune disease.
Academic Article	Impaired Fas signaling pathway is involved in defective T cell apoptosis in autoimmune murine arthritis.
Academic Article	Antibody-induced shedding of CD44 from adherent cells is linked to the assembly of the cytoskeleton.
Academic Article	Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis.
Academic Article	Increased resistance to collagen-induced arthritis in CD44-deficient DBA/1 mice.
Academic Article	Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis.
Academic Article	Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice.
Academic Article	Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis.
Academic Article	IL-4 and IL-12 regulate proteoglycan-induced arthritis through Stat-dependent mechanisms.
Academic Article	Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci.
Academic Article	IL-4 potentiates activated T cell apoptosis via an IL-2-dependent mechanism.
Academic Article	CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis.
Academic Article	Sex effect on clinical and immunologic quantitative trait loci in a murine model of rheumatoid arthritis.
Academic Article	Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones.
Academic Article	Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan.
Academic Article	TSG-6 modulates the interaction between hyaluronan and cell surface CD44.
Academic Article	Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis.
Academic Article	Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype.
Academic Article	Expression of L-selectin, but not CD44, is required for early neutrophil extravasation in antigen-induced arthritis.
Academic Article	Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.
Academic Article	Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis.
Academic Article	Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation.
Academic Article	A longitudinal study on an autoimmune murine model of ankylosing spondylitis.
Academic Article	Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation.
Academic Article	Genetic control of experimental spondylarthropathy.
Academic Article	Two major interacting chromosome loci control disease susceptibility in murine model of spondyloarthropathy.
Academic Article	Visualization and in situ analysis of leukocyte trafficking into the ankle joint in a systemic murine model of rheumatoid arthritis.
Academic Article	Expression of CD44 and L-selectin in the innate immune system is required for severe joint inflammation in the proteoglycan-induced murine model of rheumatoid arthritis.
Academic Article	Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
Academic Article	Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice.
Academic Article	Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation.
Academic Article	Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation.
Academic Article	CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis.
Academic Article	BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.
Academic Article	Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice.
Academic Article	Oral glucosamine modulates the response of the liver and lymphocytes of the mesenteric lymph nodes in a papain-induced model of joint damage and repair.
Academic Article	IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis.
Academic Article	Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.
Academic Article	Immunosenescence and its potential modulation: lessons from mouse models.
Academic Article	Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice.
Academic Article	Osteoarthritis-like damage of cartilage in the temporomandibular joints in mice with autoimmune inflammatory arthritis.
Academic Article	Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.
Academic Article	Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humans.
Academic Article	T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice.
Academic Article	Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis.
Academic Article	Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice.
Academic Article	In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis.
Academic Article	TSG-6 protein is crucial for the development of pulmonary hyaluronan deposition, eosinophilia, and airway hyperresponsiveness in a murine model of asthma.
Academic Article	The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis.
Academic Article	Differentially expressed epigenome modifiers, including aurora kinases A and B, in immune cells in rheumatoid arthritis in humans and mouse models.
Academic Article	ADAMTS5 is required for biomechanically-stimulated healing of murine tendinopathy.
Academic Article	Suppression of proteoglycan-induced autoimmune arthritis by myeloid-derived suppressor cells generated in vitro from murine bone marrow.
Academic Article	FTY720 (Gilenya) treatment prevents spontaneous autoimmune myocarditis and dilated cardiomyopathy in transgenic HLA-DQ8-BALB/c mice.
Academic Article	Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance.
Academic Article	An epitope-specific DerG-PG70 LEAPS vaccine modulates T cell responses and suppresses arthritis progression in two related murine models of rheumatoid arthritis.

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