D015632Chemicals & DrugsD03.383.725.4506170.9955591-Methyl-4-phenyl-1,2,3,6-tetrahydropyridineFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersontrue1ProfessorProfessor18484101Kanaan NM, Kordower JH, Collier TJGliaAge and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys. Glia. 2008 Aug 15; 56(11):1199-214.Glia2008-08-15T00:00:002008Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys.2124715Keshavarzian A, Haydek JM, Zepeda DO, Stinneford JG, Fields JZResearch communications in chemical pathology and pharmacologyGastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins. Res Commun Chem Pathol Pharmacol. 1990 Oct; 70(1):21-48.Res Commun Chem Pathol Pharmacol1990-10-01T00:00:001990Gastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins.KalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessor19864567Ghosh A, Roy A, Matras J, Brahmachari S, Gendelman HE, Pahan KThe Journal of neuroscience : the official journal of the Society for NeuroscienceSimvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci. 2009 Oct 28; 29(43):13543-56.J Neurosci2009-10-28T00:00:002009Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.PaulCarveyPaul Carvey41.87432800000000-87.67059170000000349203Carvey, PaulProfessorChristopherGoetzChristopher Goetz349622Goetz, ChristopherProfessor4Professor32712266Joers V, Masilamoni G, Kempf D, Weiss AR, Rotterman TM, Murray B, Yalcin-Cakmakli G, Voll RJ, Goodman MM, Howell L, Bachevalier J, Green SJ, Naqib A, Shaikh M, Engen PA, Keshavarzian A, Barnum CJ, Nye JA, Smith Y, Tansey MGNeurobiology of diseaseMicroglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series. Neurobiol Dis. 2020 10; 144:105027.Neurobiol Dis2020-07-24T00:00:002020Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series.Neurological SciencesRush University, Rush Medical CollegeJeffreyKordowerJeffrey Kordower41.87386750000000-87.67102690000000349008Kordower, JeffreyProfessorAliKeshavarzianAli Keshavarzian41.87386750000000-87.67102690000000349021Keshavarzian, AliProfessor34412704Houser MC, Caudle WM, Chang J, Kannarkat GT, Yang Y, Kelly SD, Oliver D, Joers V, Shannon KM, Keshavarzian A, Tansey MGActa neuropathologica communicationsExperimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology. Acta Neuropathol Commun. 2021 08 19; 9(1):139.Acta Neuropathol Commun2021-08-19T00:00:002021Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology.Internal Medicine, Division of Digestive Diseases and Nutritiontrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorPhysiology and Biophysics0.3557450.01374526research area of0.3387590.023559814subject area fortrue1ProfessorProfessor