D051722Chemicals & DrugsD08.811.277.656.675.374.102D09.400.430.500D12.776.395.03322640.957288ADAM ProteinsFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation ResourcePositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson31621572Malfait AM, Tortorella MDClinical and experimental rheumatologyThe "elusive DMOAD": Aggrecanase inhibition from laboratory to clinic. Clin Exp Rheumatol. 2019 Sep-Oct; 37 Suppl 120(5):130-134.Clin Exp Rheumatol2019-10-15T00:00:002019The "elusive DMOAD": Aggrecanase inhibition from laboratory to clinic.KalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessor26080426Corbett GT, Gonzalez FJ, Pahan KProceedings of the National Academy of Sciences of the United States of AmericaActivation of peroxisome proliferator-activated receptor a stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8445-50.Proc Natl Acad Sci U S A2015-06-15T00:00:002015Activation of peroxisome proliferator-activated receptor a stimulates ADAM10-mediated proteolysis of APP.GabriellaCs-SzaboGabriella Cs-Szabo349227Cs-Szabo, GabriellaProfessorRachelMillerRachel Miller349450Miller, RachelAssociate ProfessorAnnaPlaasAnna Plaas41.87352120000000-87.66713820000000349608Plaas, AnnaProfessor5Associate Professor4Professor25840345Gorski DJ, Xiao W, Li J, Luo W, Lauer M, Kisiday J, Plaas A, Sandy JMatrix biology : journal of the International Society for Matrix BiologyDeletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells. Matrix Biol. 2015 Sep; 47:66-84.Matrix Biol2015-03-31T00:00:002015Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells.33469101Zhang Y, Tian Z, Gerard D, Yao L, Shofer FS, Cs-Szabo G, Qin L, Pacifici M, Enomoto-Iwamoto MScientific reportsElevated inflammatory gene expression in intervertebral disc tissues in mice with ADAM8 inactivated. Sci Rep. 2021 01 19; 11(1):1804.Sci Rep2021-01-19T00:00:002021Elevated inflammatory gene expression in intervertebral disc tissues in mice with ADAM8 inactivated.Neurological SciencesOrthopedic SurgeryRush University, Rush Medical CollegeAnne-MarieMalfaitAnne-Marie Malfait41.87352120000000-87.66713820000000349023Malfait, Anne-MarieProfessortrue1ProfessorProfessor26410555Miller RE, Tran PB, Ishihara S, Larkin J, Malfait AMOsteoarthritis and cartilageTherapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis Cartilage. 2016 Feb; 24(2):299-306.Osteoarthritis Cartilage2015-09-26T00:00:002015Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis.true1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessorInternal Medicine, Division of Rheumatology3.060910.025909622research area of0.80180.041742562subject area fortrue1Associate ProfessorAssociate Professor