MDSumantChughSumant S. Chugh349838Chugh, SumantS.My Scopus ID is 55330649200.Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed Identifierbibo:suffixNamename suffixAddressvivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:middleNamemiddle name or initialvivo:overviewoverviewvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPersonAuthorship 363233Authorship 36324731253689Lin S, Sahai A, Chugh SS, Pan X, Wallner EI, Danesh FR, Lomasney JW, Kanwar YSThe Journal of biological chemistryWithdrawal: High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway. J Biol Chem. 2019 Jun 28; 294(26):10381.J Biol Chem2019-06-28T00:00:002019Withdrawal: High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway.31253690Sun L, Pan X, Wada J, Haas CS, Wuthrich RP, Danesh FR, Chugh SS, Kanwar YSThe Journal of biological chemistryWithdrawal: Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy. J Biol Chem. 2019 Jun 28; 294(26):10382.J Biol Chem2019-06-28T00:00:002019Withdrawal: Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy.KalipadaPahanKalipada Pahan349039Pahan, KalipadaProfessorD050199Anatomy13850.908392PodocytesMehmetAltintasMehmet Altintas349147Altintas, MehmetAssociate ProfessorStephenKorbetStephen M. Korbet349374Korbet, StephenProfessorD009404Disorders7250.958641Nephrotic Syndrome6Assistant Professor5Associate Professor4ProfessorAuthorship 385211432059999Mac? C, Del Nogal Avila M, Marshall CB, Kharlyngdoh J, Das R, Molina-Jijon E, Donoro Blazquez H, Shastry S, Soria E, Wetzels J, Dijkman H, Avila-Casado C, Clement LC, Chugh SSKidney internationalThe zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases. Kidney Int. 2020 04; 97(4):753-764.Kidney Int2019-11-26T00:00:002019The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases.D003139Disorders350.984432Common ColdD011507DisordersPhenomena18810.941486ProteinuriaNeurological SciencesRush University, Rush Medical CollegeD007678Anatomy16540.963338Kidney Glomerulustrue1Assistant ProfessorAssistant ProfessorInternal Medicine, Division of Digestive Diseases and NutritionAjaypalSinghAjaypal Singh349809Singh, AjaypalAssistant Professor1137selected publications3.035560.00644679211research areas3.660823.660821coauthor of31.8933.7021360similar toAuthorship 2023110Authorship 202797Authorship 203857Authorship 203899Authorship 204895Authorship 205032Authorship 205076Authorship 205096Authorship 205163Authorship 205355Authorship 205771Authorship 207406Authorship 208082Authorship 211613Authorship 212077Authorship 213081Authorship 213553Authorship 213887Authorship 214231Authorship 214491Authorship 214857Authorship 214982Authorship 216521Authorship 217086Authorship 217225Authorship 217526Authorship 217788Authorship 219016Authorship 219352Authorship 219438Authorship 219507Authorship 22048111880337Kanwar YS, Yang Q, Tian Y, Lin S, Wada J, Chugh S, Srivastava SKAmerican journal of physiology. Renal physiologyRelevance of renal-specific oxidoreductase in tubulogenesis during mammalian nephron development. Am J Physiol Renal Physiol. 2002 Apr; 282(4):F752-62.Am J Physiol Renal Physiol2002-04-01T00:00:002002Relevance of renal-specific oxidoreductase in tubulogenesis during mammalian nephron development.11934706Kanwar YS, Kumar A, Ota K, Lin S, Wada J, Chugh S, Wallner EIAmerican journal of physiology. Renal physiologyIdentification of developmentally regulated mesodermal-specific transcript in mouse embryonic metanephros. Am J Physiol Renal Physiol. 2002 May; 282(5):F953-65.Am J Physiol Renal Physiol2002-05-01T00:00:002002Identification of developmentally regulated mesodermal-specific transcript in mouse embryonic metanephros.11937760Wallner EI, Wada J, Lin S, Pan X, Reddy JK, Chugh SS, Kanwar YSExperimental nephrologyRenal gene expression in embryonic and newborn diabetic mice. Exp Nephrol. 2002; 10(2):130-8.Exp Nephrol2002-01-01T00:00:002002Renal gene expression in embryonic and newborn diabetic mice.12171997Sun L, Pan X, Wada J, Haas CS, Wuthrich RP, Danesh FR, Chugh SS, Kanwar YSThe Journal of biological chemistryIsolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy. J Biol Chem. 2002 Aug 16; 277(33):29953-62.J Biol Chem2002-05-24T00:00:002002Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy.12865409Liu G, Kaw B, Kurfis J, Rahmanuddin S, Kanwar YS, Chugh SSThe Journal of clinical investigationNeph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability. J Clin Invest. 2003 Jul; 112(2):209-21.J Clin Invest2003-07-01T00:00:002003Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability.14631562Chugh SS, Kaw B, Kanwar YSSeminars in nephrologyMolecular structure-function relationship in the slit diaphragm. Semin Nephrol. 2003 Nov; 23(6):544-55.Semin Nephrol2003-11-01T00:00:002003Molecular structure-function relationship in the slit diaphragm.14631566Chugh SS, Wallner EI, Kanwar YSSeminars in nephrologyRenal development in high-glucose ambience and diabetic embryopathy. Semin Nephrol. 2003 Nov; 23(6):583-92.Semin Nephrol2003-11-01T00:00:002003Renal development in high-glucose ambience and diabetic embryopathy.14707006Kanwar YS, Wada J, Lin S, Danesh FR, Chugh SS, Yang Q, Banerjee T, Lomasney JWAmerican journal of physiology. Renal physiologyUpdate of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis. Am J Physiol Renal Physiol. 2004 Feb; 286(2):F202-15.Am J Physiol Renal Physiol2004-02-01T00:00:002004Update of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis.15875217Kanwar YS, Nayak B, Lin S, Akagi S, Xie P, Wada J, Chugh SS, Danesh FRPediatric nephrology (Berlin, Germany)Hyperglycemia: its imminent effects on mammalian nephrogenesis. Pediatr Nephrol. 2005 Jul; 20(7):858-66.Pediatr Nephrol2005-05-05T00:00:002005Hyperglycemia: its imminent effects on mammalian nephrogenesis.16088221Kanwar YS, Akagi S, Sun L, Nayak B, Xie P, Wada J, Chugh SS, Danesh FRNephron. Experimental nephrologyCell biology of diabetic kidney disease. Nephron Exp Nephrol. 2005; 101(3):e100-10.Nephron Exp Nephrol2005-08-08T00:00:002005Cell biology of diabetic kidney disease.16164644Kanwar YS, Akagi S, Nayak B, Sun L, Wada J, Xie P, Thakur A, Chugh SS, Danesh FRKidney internationalRenal-specific oxidoreductase biphasic expression under high glucose ambience during fetal versus neonatal development. Kidney Int. 2005 Oct; 68(4):1670-83.Kidney Int2005-10-01T00:00:002005Renal-specific oxidoreductase biphasic expression under high glucose ambience during fetal versus neonatal development.16299691Schafernak KT, Chugh SS, Kanwar YSJournal of nephrologyCo-existent crescentic glomerulonephritis and renal amyloidosis: a case report and literature review. J Nephrol. 2005 Sep-Oct; 18(5):616-22.J Nephrol2005-09-01T00:00:002005Co-existent crescentic glomerulonephritis and renal amyloidosis: a case report and literature review.16330753Nayak B, Xie P, Akagi S, Yang Q, Sun L, Wada J, Thakur A, Danesh FR, Chugh SS, Kanwar YSProceedings of the National Academy of Sciences of the United States of AmericaModulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):17952-7.Proc Natl Acad Sci U S A2005-12-05T00:00:002005Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience.17056598Liu G, Clement LC, Kanwar YS, Avila-Casado C, Chugh SSThe Journal of biological chemistryZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. J Biol Chem. 2006 Dec 22; 281(51):39681-92.J Biol Chem2006-10-20T00:00:002006ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.17466922Chugh SSTranslational research : the journal of laboratory and clinical medicineTranscriptional regulation of podocyte disease. Transl Res. 2007 May; 149(5):237-42.Transl Res2007-05-01T00:00:002007Transcriptional regulation of podocyte disease.17591948Kanwar YS, Danesh FR, Chugh SSThe American journal of pathologyContribution of proteoglycans towards the integrated functions of renal glomerular capillaries: a historical perspective. Am J Pathol. 2007 Jul; 171(1):9-13.Am J Pathol2007-07-01T00:00:002007Contribution of proteoglycans towards the integrated functions of renal glomerular capillaries: a historical perspective.17625114Kanwar YS, Danesh FR, Chugh SSJournal of the American Society of Nephrology : JASNChimerism of the renal glomerulus revisited. J Am Soc Nephrol. 2007 Aug; 18(8):2215-7.J Am Soc Nephrol2007-07-11T00:00:002007Chimerism of the renal glomerulus revisited.18156300Kanwar YS, Wada J, Sun L, Xie P, Wallner EI, Chen S, Chugh S, Danesh FRExperimental biology and medicine (Maywood, N.J.)Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood). 2008 Jan; 233(1):4-11.Exp Biol Med (Maywood)2008-01-01T00:00:002008Diabetic nephropathy: mechanisms of renal disease progression.18753253Sun L, Xie P, Wada J, Kashihara N, Liu FY, Zhao Y, Kumar D, Chugh SS, Danesh FR, Kanwar YSJournal of the American Society of Nephrology : JASNRap1b GTPase ameliorates glucose-induced mitochondrial dysfunction. J Am Soc Nephrol. 2008 Dec; 19(12):2293-301.J Am Soc Nephrol2008-08-27T00:00:002008Rap1b GTPase ameliorates glucose-induced mitochondrial dysfunction.20566570Bell EK, Chugh SS, Cook WJNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal AssociationA case of infection-associated antiproteinase-3-negative cytoplasmic antineutrophil cytoplasmic antibody pauci-immune focal necrotizing glomerulonephritis. Nephrol Dial Transplant. 2010 Sep; 25(9):3119-23.Nephrol Dial Transplant2010-06-21T00:00:002010A case of infection-associated antiproteinase-3-negative cytoplasmic antineutrophil cytoplasmic antibody pauci-immune focal necrotizing glomerulonephritis.21151138Clement LC, Avila-Casado C, Mac? C, Soria E, Bakker WW, Kersten S, Chugh SSNature medicinePodocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 2011 Jan; 17(1):117-22.Nat Med2010-12-12T00:00:002010Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome.21252526Avila-Casado C, Fortoul TI, Chugh SSContributions to nephrologyHIV-associated nephropathy: experimental models. Contrib Nephrol. 2011; 169:270-285.Contrib Nephrol2011-01-20T00:00:002011HIV-associated nephropathy: experimental models.21974967Chugh SS, Clement LC, Mac? CAmerican journal of kidney diseases : the official journal of the National Kidney FoundationNew insights into human minimal change disease: lessons from animal models. Am J Kidney Dis. 2012 Feb; 59(2):284-92.Am J Kidney Dis2011-10-05T00:00:002011New insights into human minimal change disease: lessons from animal models.22227662Chugh SS, Clement LCNature medicineTelomerase at the center of collapsing glomerulopathy. Nat Med. 2012 Jan 06; 18(1):26-7.Nat Med2012-01-06T00:00:002012Telomerase at the center of collapsing glomerulopathy.22622461Li S, Nagothu K, Ranganathan G, Ali SM, Shank B, Gokden N, Ayyadevara S, Megyesi J, Olivecrona G, Chugh SS, Kersten S, Portilla DAmerican journal of physiology. Renal physiologyReduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury. Am J Physiol Renal Physiol. 2012 Aug 01; 303(3):F437-48.Am J Physiol Renal Physiol2012-05-23T00:00:002012Reduced kidney lipoprotein lipase and renal tubule triglyceride accumulation in cisplatin-mediated acute kidney injury.24317117Clement LC, Mac? C, Avila-Casado C, Joles JA, Kersten S, Chugh SSNature medicineCirculating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. 2014 Jan; 20(1):37-46.Nat Med2013-12-08T00:00:002013Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome.24611049Chugh SS, Mac? C, Clement LC, Del Nogal Avila M, Marshall CBFrontiers in pharmacologyAngiopoietin-like 4 based therapeutics for proteinuria and kidney disease. Front Pharmacol. 2014; 5:23.Front Pharmacol2014-02-25T00:00:002014Angiopoietin-like 4 based therapeutics for proteinuria and kidney disease.24700796Wiggins RC, Alpers CE, Holzman LB, He JC, Salant DJ, Chugh SS, Natarajan R, Trachtman H, Brasile L, Star RA, Rys-Sikora KE, Moxey-Mims MM, Flessner MFClinical journal of the American Society of Nephrology : CJASNGlomerular disease: looking beyond pathology. Clin J Am Soc Nephrol. 2014 Jun 06; 9(6):1138-40.Clin J Am Soc Nephrol2014-04-03T00:00:002014Glomerular disease: looking beyond pathology.24854282Mac? C, Chugh SSJournal of the American Society of Nephrology : JASNNephrotic syndrome: components, connections, and angiopoietin-like 4-related therapeutics. J Am Soc Nephrol. 2014 Nov; 25(11):2393-8.J Am Soc Nephrol2014-05-22T00:00:002014Nephrotic syndrome: components, connections, and angiopoietin-like 4-related therapeutics.25005737Clement LC, Mac? C, Del Nogal Avila M, Marshall CB, Chugh SSTranslational research : the journal of laboratory and clinical medicineThe proteinuria-hypertriglyceridemia connection as a basis for novel therapeutics for nephrotic syndrome. Transl Res. 2015 Apr; 165(4):499-504.Transl Res2014-06-18T00:00:002014The proteinuria-hypertriglyceridemia connection as a basis for novel therapeutics for nephrotic syndrome.25984117Saxena N, Chugh SS, Centor RNDT plusCoagulase-negative staphylococcus-oftentimes a virulent masquerader. NDT Plus. 2011 Feb; 4(1):81-2.NDT Plus2010-10-21T00:00:002010Coagulase-negative staphylococcus-oftentimes a virulent masquerader.27147672Del Nogal-Avila M, Donoro-Blazquez H, Saha MK, Marshall CB, Clement LC, Mac? CE, Chugh SSAmerican journal of physiology. Renal physiologyNovel therapeutic approaches for chronic kidney disease due to glomerular disorders. Am J Physiol Renal Physiol. 2016 07 01; 311(1):F63-5.Am J Physiol Renal Physiol2016-05-04T00:00:002016Novel therapeutic approaches for chronic kidney disease due to glomerular disorders.true1ProfessorProfessortrue1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessorInternal Medicine, Division of NephrologyLionelClementLionel Clement350003Clement, LionelAssistant ProfessorAuthorship 474621Authorship 475601537040185Del Nogal Avila M, Das R, Kharlyngdoh J, Molina-Jijon E, Donoro Blazquez H, Gambut S, Crowley M, Crossman DK, Gbadegesin RA, Chugh SS, Chugh SS, Avila-Casado C, Mac? C, Clement LC, Chugh SSJCI insightCytokine storm-based mechanisms for extrapulmonary manifestations of SARS-CoV-2 infection. JCI Insight. 2023 05 22; 8(10).JCI Insight2023-05-22T00:00:002023Cytokine storm-based mechanisms for extrapulmonary manifestations of SARS-CoV-2 infection.37795536Chugh SS, Clement LCAmerican journal of physiology. Renal physiology"Idiopathic" minimal change nephrotic syndrome: a podocyte mystery nears the end. Am J Physiol Renal Physiol. 2023 12 01; 325(6):F685-F694.Am J Physiol Renal Physiol2023-10-05T00:00:002023"Idiopathic" minimal change nephrotic syndrome: a podocyte mystery nears the end.