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Ke Zhu

TitleInstructor
InstitutionRush University, Rush Medical College
DepartmentOrthopedic Surgery
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    My ORCID is 0000-0002-2321-5085.
    My Scopus ID is 55303347800.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gao AX, Xia TC, Mak MS, Zhu KY, Dong TT, Tsim KW. A Herbal Mixture of Sesami Semen Nigrum and Longan Arillus Induces Neurite Outgrowth in Cultured Neurons and Shows Anti-Depression in Chronic Mild Stress-Induced Rats. Evid Based Complement Alternat Med. 2022; 2022:8809546. PMID: 35754681.
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    2. Chan GK, Wu R, Chen VP, Zhu KY, Du Y. Quality Control on Herbal Medicine and Its Application. Evid Based Complement Alternat Med. 2018; 2018:3294398. PMID: 29736178.
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    3. Yu J, Guo J, Tao W, Liu P, Shang E, Zhu Z, Fan X, Shen J, Hua Y, Zhu KY, Tang Y, Duan JA. Gancao-Gansui combination impacts gut microbiota diversity and related metabolic functions. J Ethnopharmacol. 2018 Mar 25; 214:71-82. PMID: 29198875.
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    4. Li JP, Liu Y, Guo JM, Shang EX, Zhu ZH, Zhu KY, Tang YP, Zhao BC, Tang ZS, Duan JA. A Comprehensive Strategy to Evaluate Compatible Stability of Chinese Medicine Injection and Infusion Solutions Based on Chemical Analysis and Bioactivity Assay. Front Pharmacol. 2017; 8:833. PMID: 29187820.
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    5. Yu JG, Guo J, Zhu KY, Tao W, Chen Y, Liu P, Hua Y, Tang Y, Duan JA. How impaired efficacy happened between Gancao and Yuanhua: Compounds, targets and pathways. Sci Rep. 2017 06 19; 7(1):3828. PMID: 28630457.
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    6. Li JP, Guo JM, Hua YQ, Zhu KY, Tang YP, Zhao BC, Jia LF, Zhao J, Tang ZS, Duan JA. The mixture of Salvia miltiorrhiza-Carthamus tinctorius (Danhong injection) alleviates low-dose aspirin induced gastric mucosal damage in rats. Phytomedicine. 2016 Jun 01; 23(6):662-71. PMID: 27161407.
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    7. Leung KW, Wong ZC, Ho JY, Yip AW, Ng JS, Ip SP, Ng WY, Ho KK, Duan R, Zhu KY, Tsim KW. Determination of hair ketamine cut-off value from Hong Kong ketamine users by LC-MS/MS analysis. Forensic Sci Int. 2016 Feb; 259:53-8. PMID: 26750989.
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    8. Li J, Guo J, Shang E, Zhu Z, Zhu KY, Li S, Zhao B, Jia L, Zhao J, Tang Z, Duan J. A metabolomics strategy to explore urinary biomarkers and metabolic pathways for assessment of interaction between Danhong injection and low-dose aspirin during their synergistic treatment. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 15; 1026:168-175. PMID: 26265434.
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    9. Yan L, Xu SL, Zhu KY, Lam KY, Xin G, Maiwulanjiang M, Li N, Dong TT, Lin H, Tsim KW. Optimizing the compatibility of paired-herb in an ancient Chinese herbal decoction Kai-Xin-San in activating neurofilament expression in cultured PC12 cells. J Ethnopharmacol. 2015 Mar 13; 162:155-62. PMID: 25560671.
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    10. Xin GZ, Lam YC, Maiwulanjiang M, Chan GK, Zhu KY, Tang WL, Dong TT, Shi ZQ, Li P, Tsim KW. Authentication of Bulbus Fritillariae Cirrhosae by RAPD-derived DNA markers. Molecules. 2014 Mar 20; 19(3):3450-9. PMID: 24658569.
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    11. Chen J, Maiwulanjiang M, Lam KY, Zhang WL, Zhan JY, Lam CT, Xu SL, Zhu KY, Yao P, Lau DT, Dong TT, Tsim KW. A standardized extract of the fruit of Ziziphus jujuba (Jujube) induces neuronal differentiation of cultured PC12 cells: a signaling mediated by protein kinase A. J Agric Food Chem. 2014 Feb 26; 62(8):1890-7. PMID: 24520858.
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    12. Xu SL, Zhu KY, Bi CW, Yan L, Men SW, Dong TT, Tsim KW. Flavonoids, derived from traditional Chinese medicines, show roles in the differentiation of neurons: possible targets in developing health food products. Birth Defects Res C Embryo Today. 2013 Dec; 99(4):292-9. PMID: 24339039.
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    13. Xu SL, Zhu KY, Bi CW, Choi RC, Miernisha A, Yan AL, Maiwulanjiang M, Men SW, Dong TT, Tsim KW. Flavonoids induce the expression of synaptic proteins, synaptotagmin, and postsynaptic density protein-95 in cultured rat cortical neuron. Planta Med. 2013 Dec; 79(18):1710-4. PMID: 24243544.
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    14. Zhu KY, Xu SL, Choi RC, Yan AL, Dong TT, Tsim KW. Kai-xin-san, a chinese herbal decoction containing ginseng radix et rhizoma, polygalae radix, acori tatarinowii rhizoma, and poria, stimulates the expression and secretion of neurotrophic factors in cultured astrocytes. Evid Based Complement Alternat Med. 2013; 2013:731385. PMID: 24222781.
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    15. Maiwulanjiang M, Zhu KY, Chen J, Miernisha A, Xu SL, Du CY, Lau KK, Choi RC, Dong TT, Aisa HA, Tsim KW. Song bu li decoction, a traditional uyghur medicine, protects cell death by regulation of oxidative stress and differentiation in cultured PC12 cells. Evid Based Complement Alternat Med. 2013; 2013:687958. PMID: 24198845.
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    16. Choi RC, Zhu JT, Yung AW, Lee PS, Xu SL, Guo AJ, Zhu KY, Dong TT, Tsim KW. Synergistic Action of Flavonoids, Baicalein, and Daidzein in Estrogenic and Neuroprotective Effects: A Development of Potential Health Products and Therapeutic Drugs against Alzheimer's Disease. Evid Based Complement Alternat Med. 2013; 2013:635694. PMID: 24058373.
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    17. Chen J, Li Z, Maiwulanjiang M, Zhang WL, Zhan JY, Lam CT, Zhu KY, Yao P, Choi RC, Lau DT, Dong TT, Tsim KW. Chemical and biological assessment of Ziziphus jujuba fruits from China: different geographical sources and developmental stages. J Agric Food Chem. 2013 Jul 31; 61(30):7315-24. PMID: 23841724.
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    18. Xu SL, Bi CW, Choi RC, Zhu KY, Miernisha A, Dong TT, Tsim KW. Flavonoids induce the synthesis and secretion of neurotrophic factors in cultured rat astrocytes: a signaling response mediated by estrogen receptor. Evid Based Complement Alternat Med. 2013; 2013:127075. PMID: 23878590.
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    19. Zhan JY, Zhang WL, Zheng KY, Zhu KY, Chen JP, Chan PH, Dong TT, Choi RC, Lam H, Tsim KW, Lau DT. Chemical changes of Angelicae Sinensis Radix and Chuanxiong Rhizoma by wine treatment: chemical profiling and marker selection by gas chromatography coupled with triple quadrupole mass spectrometry. Chin Med. 2013 Jun 06; 8(1):12. PMID: 23738580.
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    20. Zhan JY, Zheng KY, Zhu KY, Zhang WL, Bi CW, Chen JP, Du CY, Dong TT, Lau DT, Tsim KW. Importance of wine-treated Angelica Sinensis Radix in Si Wu Tang, a traditional herbal formula for treating women's ailments. Planta Med. 2013 May; 79(7):533-7. PMID: 23457023.
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    21. Zhang WL, Zheng KY, Zhu KY, Zhan JY, Bi CW, Chen JP, Dong TT, Choi RC, Lau DT, Tsim KW. Chemical and biological assessment of angelica roots from different cultivated regions in a chinese herbal decoction danggui buxue tang. Evid Based Complement Alternat Med. 2013; 2013:483286. PMID: 23476692.
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    22. Zhu KY, Mao QQ, Ip SP, Choi RC, Dong TT, Lau DT, Tsim KW. A standardized chinese herbal decoction, kai-xin-san, restores decreased levels of neurotransmitters and neurotrophic factors in the brain of chronic stress-induced depressive rats. Evid Based Complement Alternat Med. 2012; 2012:149256. PMID: 22973399.
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    23. Zhang WL, Zheng KY, Zhu KY, Zhan JY, Bi CW, Chen JP, Du CY, Zhao KJ, Lau DT, Dong TT, Tsim KW. Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications. Phytomedicine. 2012 Aug 15; 19(11):1042-8. PMID: 22902230.
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    24. Xu SL, Choi RC, Zhu KY, Leung KW, Guo AJ, Bi D, Xu H, Lau DT, Dong TT, Tsim KW. Isorhamnetin, A Flavonol Aglycone from Ginkgo biloba L., Induces Neuronal Differentiation of Cultured PC12 Cells: Potentiating the Effect of Nerve Growth Factor. Evid Based Complement Alternat Med. 2012; 2012:278273. PMID: 22761636.
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    25. Zheng KY, Choi RC, Guo AJ, Bi CW, Zhu KY, Du CY, Zhang ZX, Lau DT, Dong TT, Tsim KW. The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: a synergistic action of an ancient herbal decoction Danggui Buxue Tang. J Pharm Biomed Anal. 2012 Nov; 70:671-9. PMID: 22704738.
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    26. Zheng KY, Zhang ZX, Guo AJ, Bi CW, Zhu KY, Xu SL, Zhan JY, Lau DT, Dong TT, Choi RC, Tsim KW. Salidroside stimulates the accumulation of HIF-1a protein resulted in the induction of EPO expression: a signaling via blocking the degradation pathway in kidney and liver cells. Eur J Pharmacol. 2012 Mar 15; 679(1-3):34-9. PMID: 22309741.
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    27. Zhu KY, Leung KW, Ting AK, Wong ZC, Ng WY, Choi RC, Dong TT, Wang T, Lau DT, Tsim KW. Microfluidic chip based nano liquid chromatography coupled to tandem mass spectrometry for the determination of abused drugs and metabolites in human hair. Anal Bioanal Chem. 2012 Mar; 402(9):2805-15. PMID: 22281681.
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    28. Zhan JY, Zheng KY, Zhu KY, Bi CW, Zhang WL, Du CY, Fu Q, Dong TT, Choi RC, Tsim KW, Lau DT. Chemical and biological assessment of Angelicae Sinensis Radix after processing with wine: an orthogonal array design to reveal the optimized conditions. J Agric Food Chem. 2011 Jun 08; 59(11):6091-8. PMID: 21520895.
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    29. Zhu KY, Fu Q, Leung KW, Wong ZC, Choi RC, Tsim KW. The establishment of a sensitive method in determining different neurotransmitters simultaneously in rat brains by using liquid chromatography-electrospray tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Apr 01; 879(11-12):737-42. PMID: 21377429.
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    30. Zheng KY, Choi RC, Cheung AW, Guo AJ, Bi CW, Zhu KY, Fu Q, Du Y, Zhang WL, Zhan JY, Duan R, Lau DT, Dong TT, Tsim KW. Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1a. J Agric Food Chem. 2011 Mar 09; 59(5):1697-704. PMID: 21309574.
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    31. Zheng KY, Guo AJ, Bi CW, Zhu KY, Chan GK, Fu Q, Xu SL, Zhan JY, Lau DT, Dong TT, Choi RC, Tsim KW. The extract of Rhodiolae Crenulatae Radix et Rhizoma induces the accumulation of HIF-1a via blocking the degradation pathway in cultured kidney fibroblasts. Planta Med. 2011 Jun; 77(9):894-9. PMID: 21157678.
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    32. Zhu KY, Fu Q, Xie HQ, Xu SL, Cheung AW, Zheng KY, Luk WK, Choi RC, Lau DT, Dong TT, Jiang ZY, Chen JJ, Tsim KW. Quality assessment of a formulated Chinese herbal decoction, Kaixinsan, by using rapid resolution liquid chromatography coupled with mass spectrometry: A chemical evaluation of different historical formulae. J Sep Sci. 2010 Dec; 33(23-24):3666-74. PMID: 21077129.
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    33. Zhu KY, Leung KW, Ting AK, Wong ZC, Fu Q, Ng WY, Choi RC, Dong TT, Wang T, Lau DT, Tsim KW. The establishment of a highly sensitive method in detecting ketamine and norketamine simultaneously in human hairs by HPLC-Chip-MS/MS. Forensic Sci Int. 2011 May 20; 208(1-3):53-8. PMID: 21112706.
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    34. Zheng KY, Choi RC, Xie HQ, Cheung AW, Guo AJ, Leung KW, Chen VP, Bi CW, Zhu KY, Chan GK, Fu Q, Lau DT, Dong TT, Zhao KJ, Tsim KW. The expression of erythropoietin triggered by danggui buxue tang, a Chinese herbal decoction prepared from radix Astragali and radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells. J Ethnopharmacol. 2010 Oct 28; 132(1):259-67. PMID: 20723591.
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    35. Xie HQ, Leung KW, Chen VP, Chan GK, Xu SL, Guo AJ, Zhu KY, Zheng KY, Bi CW, Zhan JY, Chan WK, Choi RC, Tsim KW. PRiMA directs a restricted localization of tetrameric AChE at synapses. Chem Biol Interact. 2010 Sep 06; 187(1-3):78-83. PMID: 20178777.
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    36. Xie HQ, Liang D, Leung KW, Chen VP, Zhu KY, Chan WK, Choi RC, Massouli? J, Tsim KW. Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons. J Biol Chem. 2010 Apr 09; 285(15):11537-46. PMID: 20147288.
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    37. Tsim KW, Leung KW, Mok KW, Chen VP, Zhu KY, Zhu JT, Guo AJ, Bi CW, Zheng KY, Lau DT, Xie HQ, Choi RC. Expression and Localization of PRiMA-linked globular form acetylcholinesterase in vertebrate neuromuscular junctions. J Mol Neurosci. 2010 Jan; 40(1-2):40-6. PMID: 19680821.
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